Endocrine triads/tetrads

Question 1

Hypothyroidism (2x3)

Answer 1

• Tiredness
  
  • Husky voice
  • Cold intolerance
  • Physical slowing
  • Mental slowing
  • Facial puffiness

Question 2

Hyperthyroidism (2x3)

Answer 2

• Anxiety
  
  • Weight loss
  • Muscle weakness
  • Sweaty hands
  • Loose frequent bowel motions
  • Palpitations

Question 3

Acromegaly (x4)

Answer 3

• Nasal problems
  
  • Fitting problems (shoes, gloves, rings)
  • Weakness
  • Sweating

Question 4

Addison Disease (3 +/- 4)

Answer 4

• Fatigue/weakness
  
  • Anorexia & nausea
  • Dizziness
  • +/-
    
    • Skin discolouration
    • Abdominal pain
    • Weight loss
    • Diarrhoea

Question 5

Cushing Disease (2x3)

Answer 5

• Plethoric moon face
  
  • Thin extremities
  • Muscle weakness
  • Hirsutism
  • Abdominal striae
  • Hypertension

Question 6

Hypopituitarism (female x3 & male x3)

Answer 6

• Female
  * Amenorrhoea
  * Loss of axillary and pubic hair
  * Breast atrophy
  • Male
    
    • Reduced libido
    • Impotence
    • Loss of body hair

Question 7

Diabetes insipidus (x3)

Answer 7

• Weakness
  
  • Polyuria
  • Polydipsia (intense craving for ice water)

Question 8

Hypercalcaemia (x3)

Answer 8

• Weakness
  
  • Constipation
  • Polyuria (eg primary hyperparathyroidism)

Question 9

Hyperparathyroidism (x4)

Answer 9

• Bones
  
  • Moans
  • Stones
  • Abdominal groans

Question 10

Hypocalcaemia (x3)

Answer 10

• Cramps
  
  • Cognitive dysfunction (eg confusion)
  • Tetany

Question 11

Hyperprolactinaemia (3 + female x2 + male x2)

Answer 11

• Both sexes
  * Reduced libido
  * Subfertility
  * Galactorrhoea
  • Females
    
    • Amenorrhoea
    • Oligomenorrhoea
  • Males
    
    • ED
    • Reduced facial hair

Question 12

Diabetes (x4)

Answer 12

• Fatigue & tiredness
  
  • Polydipsia
  • Polyuria
  • Weight loss (indicates type 1)