Endocrine System Flashcards
What is the difference between exocrine glands and endocrine glands?
Exocrine: release ENZYMES into the the external environment via ducts
Endocrine: release HORMONES directly into the bloodstream
What is true of all hormones?
They all act by binding to protein receptors
What are the 3 types of hormones?
1) peptides
2) steroids
3) tyrosine derivatives
What are the common enzymes that activate the 2nd messenger system?
cAMP, cGMP, calmodulin
Where are all peptide hormones manufactured?
the rough ER
Where are steroid hormones manufactured?
the smooth ER
Most steroid hormones regulate enzyme activity at the level of…….?
transcription
What are the main solubility / transport differences between peptide hormones and steroid hormones?
Peptides: are water soluble so they can travel through the bloodstream without a proteint carrier, but bind to the OUTSIDE of the effector
Steroids: are hydrophobic so they need a carrier protein to dissolve in the blood, but can DIFFUSE THROUGH the cell membrane an their effector
What are the main steroid hormones?
1) gonadal hormones: estrogen, progesterone, testosterone
2) glucocorticoid: Cortisol
3) mineralcorticoids: Aldosterone
What are the tyrosine derivative hormones?
1) thyroids: T3 & T4
2) catecholamines: epinephrine, norepinephrine
What is the difference between the nervous system and the endocrine system?
The nervous system is fast and specific, while the endocrine system in slower and more generalized
What is another term for the anterior pituitary?
“Adenohypophysis”
What are the 6 hormones released by the anterior pituitary?
1) Follicle Stimulating Hormone, FSH
2) Luteinizing Hormone, LH
3) Adrenocorticotropic Hormone, ACTH
4) Thyroid Stimulating Hormone, TSH
5) Prolactin
6) human Growth Hormone, hGH
“FLAT PiG”
What is another name of hGH?
somatotropin
True or False: hGH affects nearly all cells of the body?
True
How does hGH stimulate growth?
- increasing mitosis
- increasing rate of protein synthesis
- increasing use of FA for energy use, thus decreasing the use of Glucose
What 2nd messenger enzyme is used with ACTH?
cAMP
What does ACTH release?
stimulates the adrenal cortex to release Cortisol, a stress hormone
What 2nd messenger enzyme is used with TSH?
cAMP
What is the primary function of Prolactin?
milk production, though unless a woman in pregnant the hypothalamus mainly works to inhibit this particular peptide hormone