Endocrine system Flashcards

1
Q

What are the three mechanisms of intercellular communication?

A

Paracrine, Autocrine, Endocrine

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2
Q

What does the amount of hormone in the blood depend on?

A

The rate of hormone secretion and rate of removal from blood

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3
Q

What do beta cells secrete?

A

Insulin

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4
Q

What do alpha cells secrete?

A

Glucagon

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5
Q

Where are alpha and beta cells found?

A

The pancreas

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6
Q

What does insulin do?

A

When insulin is secreted into the blood stream it causes the liver and muscles to uptake glucose, therefore decrease the blood glucose concentration

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7
Q

What does glucagon do?

A

Targets the liver cell to breakdown glycogen (stored form of glucose) and synthesis more glucose and ketone to increase the blood glucose concentration

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8
Q

What is hyper and hypo secretion?

A

When there is too much or too little hormone being produced

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9
Q

What is hypo and hyper sensitivity

A

When hormone receptors respond too much or have little / no response

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10
Q

What is type 1 diabetes?

A

Hypo-secretion: too little or no insulin is secreted so glucose levels are very high in someone who has this

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11
Q

What is type 2 diabetes

A

hyposensitive: too little or no response to insulin from the receptor

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12
Q

What are some outcomes of diabetes

A

Glucosuria, polyuria, polydipsia, disrupted blood flow, diabetic neuropathy

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13
Q

Where is the pituitary gland located?`

A

At the base of the brain and is attached to the hypothalamus

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14
Q

How is the pituitary gland activated?

A

When the hypothalamus receives neural input it will stimulate the pituitary gland to secrete hormones

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15
Q

What are some anatomical features of the posterior lobe of the pituitary gland?

A

It is connected to the hypothalamus by neurons, the cells bodies in the hypothalamus and axons terminate in the posterior lobe. And secretes hormones into the blood.

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16
Q

Where are posterior pituitary hormones produced and stored?

A

They are made in the cell body of the neuron in the hypothalamus, travel down the axon and are stored there until required

17
Q

What two hormones are released by the posterior pituitary gland?

A

Antidiuretic hormone and oxytocin

18
Q

What is antidiuretic hormone?

A

It is a hormone that stimulates the kidneys to reabsorb water

19
Q

What is oxytocin

A

It stimulates the contraction of uterine muscles during childbirth and stimulates milk release in breastfeeding

20
Q

Describe the anatomical features of the anterior lobe of the pituitary gland

A

It is connected to the hypothalamus by blood vessels. with nerual input within the hypothalamus, Hypothalamic hormones stimulate or inhibit release of stored hormones from specific cells

21
Q

How is growth hormone secreted?

A

Via a negative feedback system, the hypothalamus will secrete GH-RH which causes the anterior pituitary gland to secrete growth hormone.

22
Q

What are the indirect effects of growth hormone?

A

Promotes the growth of bones, muscle and other tissues by causing release of somatomedin C which promotes cell division.