Endocrine System Flashcards
Proximity of cells to each other–DISTANT
Transmission pathway–CIRCULATING SYSTEM
Chemical Mediator–HORMONE
ENDCORINE
Proximity of cells to each other–LOCAL, NEARBY TISSUE
Transmission Pathway–ISF
Chemical Mediator–PARACRINE
PARACRINE
Proximity of cells to each other–SAME CELL (LOCAL)
Transmission pathway–ISF
Chemical Mediator–AUTOCRINE
AUTOCRINE
Proximity of cells to each other–ADJACENT CELL MEMBRANES (FUSED)
Transmission Pathway–GAP JUNCTIONS
Chemical Mediator–VARIOUS IONS
GAP JUNCTIONS
The endocrine system coordinates body cavities by means of ______ signals
Chemical
Exocrine glands release their secretions into a _____
Duct
Target Tissue
Specific cells/tissues influenced by a hormone
Target tissues posses proteins called_____ that specifically bind to that hormone
Receptors
Target Cell Specificity
Hormones affect only specific target tissues that have specific receptors for that hormone.
Why is the Target Cell Specificity central to the function of the endocrine system
Enables endocrine system to release hormones systematically without creating chaos
Hormones are the key that will only fit in to a certain receptor (LOCK) and “open” it to create a reaction in the target cell
“lock and key”
When a hormone is deficient, the # of receptors increase
UP Regulation
UP=More sensitve
If a hormone is present in excess, the # of target cell receptors may decrease
Down Regulation
Down=Less sensitive
Hormones derived from the amino acid Tyrosine include______ a group that includes epinephrine, norepinephrine, and dopamine
Catacholamine
Amine hormone based on tyrosine and adding the mineral iodine is
Thyroid Hormone
Peptide Hormones
Hormones composed of short amino acid chains
Protein Hormones
Hormones composed of long, more complex amino acid chains
Glycoprotein Hormones
Carbohydrate side chains
Examples of Peptide Hormones
ADH
Oxytocin
Antidiuretic Hormone
Examples of Protein Hormones
Human Growth (GH)
Insulin
TSH
Steroid Hormones are derived from _____
Cholesterol
4 Organs that secrete steroid hormones
Adrenal Cortex
Testes–Testosterone
Ovaries–Estrogen
Calcitrol
The greatest variety of Hormones belong to which chemical group?
Proteins/Peptides
Steroid, thyroid (testosterone)
Bound to plasma protein
Inside target cells
Directly stimulate protein synthesis
LIPID SOLUBLE HORMONES
Amines, peptides/proteins (melatonin)
Free molecule
Surface of plasma membrane
Activates second messengers system inside cell
WATER-SOLUBLE HORMONES
Changes rate or strength of contraction
Type of response when a hormone binds to a target cell of a MUSCLE CELL
Changes rate of synthesis or activity of specific proteins within target cells
Type of response when a hormone binds to a target cell of a SECRETORY CELL
Change permeability of cell membrane
change rate of specific metabolic reactions
Type of response when a hormone binds to a target cell for MOST CELLS
Actions of some hormones on target cells require a simultaneous or recent exposure to a second hormone
Permissive effect
Effect of 2 hormones acting together is greater or more extensive than the effect of each hormone acting alone
Synergistic effect
One hormone opposes the actions of another hormone (opposite effect)
Antagonistic effect
3 types of inputs that can regulate the rate of hormone secretion
Signals from nervous system
Chemical changes in the blood
Other hormones