Endocrine System Flashcards
Functions
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Thyrotropin (TRH)
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Growth hormone - releasing hormone (GHRH)
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Growth hormone - inhibiting hormone (GHIH)
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Corticotropin - releasing hormone (CRH)
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Gonadotropin - Releasing hormone (GnRH)
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Prolactin - Inhibiting hormone (PIH)
Release Location: Post. Pituitary
Target: Uterus, breast
Trigger: Labor, sucking of infant at breast
Effect: Uterine contractions, milk ejection, ejaculation, sexual affection
Hypo: NA
Hyper: NA
Oxytocin (Dopamine)
(OT)
Release Location: Post. Pituitary
Target: Kidneys
Trigger: Increase of ions in blood
Effect: Kidney tubules reabsorb water from forming urine back into blood
Hypo: Diabetes insipidus
Hyper: SIADH
Antidiuretic hormone
(ADH)
Release Location: Ant. Pituitary
Target: Adrenal cortex
Trigger: CRH, hypoglycemia
Effect: Release of glucocorticoids
Hypo: Rare
Hyper: Cushing’s disease
Adrenocorticotropic hormone (ACTH)
Release Location: Ant. Pituitary
Target: Liver, bone, cartilage, muscle
Trigger: Low blood levels of GH, Deep sleep, GHRH release, exercise
Effect: Increase blood glucose, increase fat breakdown
Hypo: Pituitary dwarfism in children
Hyper: Gigantism in children, acromegaly in adults
Growth hormone
(GH)
Release Location: Ant. Pituitary
Target: Thyroid gland
Trigger: TRH, cold temperatures
Effect: Growth of thyroid, secretion of thyroid hormone
Hypo: Hypothyroidism; myxedema
Hyper: Hyperthyroidism; Grave’s disease
Thyroid stimulating hormone
(TSH)
Release Location: Ant. Pituitary
Target: Ovaries, testes
Trigger: GnRH
Effect: Growth of ovarian follicle maturation; sperm production
Hypo: No sexual maturation
Hyper: NA
Follicle stimulating hormone
(FSH)
Release Location: Ant. Pituitary
Target: Ovaries, testes
Trigger: GnRH
Effect: Ovulation; estrogen and progesterone production; testosterone production
Hypo: No sexual maturation
Hyper: NA
Luteinizing hormone
(LH)
Release Location: Ant. Pituitary
Target:
Trigger: Decrease in PIH, estrogen, suckling of infant at breast
Effect: Lactation in females
Hypo: Poor milk production during breastfeeding
Hyper: Inappropriate milk production; Cessation of menses
Prolactin
(PRL)
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Epinephrine