Endocrine system Flashcards
lacks structural continuity and hierarchy
Endocrine System
Maintain body homeostasis
Endocrine Organs
Goes hand in hand with the nervous system
Endocrine System
Structure that controls mostly brain and spinal cord, quick acting system
Nervous System
Other organs communicate with other organs, slow acting and depends on the Concentration Hormones
Endocrine System
chemical substances secreted by endocrine cells
Hormones
Extracellular fluids that regulate metabolic activity of
other cells in the body is the location of secretion of?
Hormones
Three classification of Hormones
Amino acid-based molecules, steroids and prostaglandin
Water-soluble, proteins, peptides, amines
Amino-acid based Molecules
■ Made from cholesterol
■ Sex hormones made by gonads (ovaries and testes)
■ Hormones produced by adrenal cortex
■ Intercellular signaling
Steroids
■ Lipid-soluble
■ Intracellular signaling
■ Made from highly active
lipids
■ Can be found released by all membranes
Prostaglandin
Chemical signaling within the cell
Intracellular
2 Types of chemical signals
Intracellular and Intercellular
How the nucleus
controls actions within
the cell
Intracelullar
A specific cell secretes hormones that influence other cells
Intercellular
In between cells
Intercellular
Types of Intercellular
Autocrine and Paracrine
Release by cells and have local effects on the
same cell type
Autocrine
Released by cells
that affect other cell types in close proximity
Paracrine
Needed for the target
cell to respond
Receptors
Where hormones attach
receptors
Influence of hormones
Binding
Group of cells that respond to specific hormones
Target tissue
Arouse the body by altering cellular activity
Hormones
Increasing or decreasing rate of a normal metabolic process
Altering Cellular activity
Change permeability of plasma membrane potential
Hormones
Active or inactivate enzymes
Hormones
Stimulate or inhibit cell division
Hormones
Promote or inhibit secretion of
a product
Hormones
Turn on or off transcription of
certain genes
Hormones
Reproduction (mitosis, cellular
division)
Hormones
Growth and development
Hormones
Mobilization of body defenses
Hormones
Mobilization of body defenses
Hormones
Regulation of metabolism
Hormones
Steroid is diffused through the plasma membrane as they are lipid soluble
Step 1 of Direct Gene Activation
Used by steroid hormones
Direct Gene Activation
Steroids are lipid-soluble
molecules hence, they can diffuse through the plasma membrane of target cells
Direct Gene Activation
Steroid hormone enters the nucleus
Step 2 Direct Gene Activation
Steroid binds to a specific hormone receptor
Step 3 Direct Gene Activation
Activating genes to transcribe mRNA
Step 4 of Direct Gene Activation
Hormone-receptor complex binds to specific sites on the cell’s DNA
Step 5 of Direct Gene Activation
mRNA is translated in cytoplasm
Step 6 of Direct Gene Activation
Synthesis of proteins
Step 7 of Direct Gene Activation
Indirect pathway used by steroid to influence cell activity
Second-Messenger System