Endocrine System Flashcards
The regulatory hormones of the hypothalamus target what gland?
Anterior pituitary
What is not a hormone produced by the hypothalamus
Melatonin
If an individual experiences lack of sexual development/infertility, what hormone might they be lacking
GnRh
T/F the primary target of the regulatory hormones is the posterior pituitary
False
An increase in blood osmolality might trigger the release of what hormone produced by the
hypothalamus?
ADH
An individual that has gigantism might have a disorder called _________ that occurs when the
_________ produces too much ________
Acromegaly, pituitary gland, growth hormone
An increase in blood osmolality might trigger the release of what hormone produced by the hypothalamus
ADH
What hormone is synthesized by the hypothalamus and involved in a positive feedback loop
Oxytocin
What is the target of the regulatory hormones released by the hypothalamus?
Anterior pituitary
Match the hormones to their functions
Regulatory - Anterior Pituitary
ADH - stimulates thirst center to increase fluid intake
Oxytocin - contraction of smooth muscle in the uterus
Melatonin - regulates cardiac rhythm
Regulatory hormone in the _______ target the _____ in order to control the release of hormones from the anterior pituitary
Hypothalamus, anterior pituitary
What statement is true
Both the hypothalamus and the pineal gland are located in the brain
What are the targets of ADH
Hypothalamus, kidney, blood vessels
Homeostatic mechanisms controlling growth hormone involve negative feedback by GH and what other hormone?
GHIH
T/F: The primary target of antidiuretic hormone is the kidney, hypothalamus, and blood vessels
True
What part of the brain is oxytocin secreted from?
Posterior pituitary
What are the functions of melatonin
Regulates cardiac rhythm, sexual maturation
The Hypothalamus is located _________ to the thalamus, and ________ to the pituitary gland
Inferior, posterior
This hormone produced by the hypothalamus targets the uterus, breasts, and the brain
Oxytocin
Place the following events in order regarding the release and effects of Growth Hormone
A. The hypothalamus responds to various stimuli
B. GH stimulates hepatocytes to release insulin-like growth factors (IGFs) into the blood
C. In response to GHRH the anterior pituitary gland releases growth hormone
D. A variable influences the release of GHRH from the hypothalamus
E. Both GH and IGFs stimulate target (effector) cells
F. Growth is stimulated; nutrient release into the bloodstream
G. Increased GH and IGF levels inhibit GHRH release; increased GH levels inhibit further release of GH
H. The hypothalamus releases GHRH into the hypothalamo-hypophyseal portal system
The Hypothalamus connects to the _____ via the hypothalamo-hypophyseal portal system
Anterior pituitary gland
T/F: The anterior pituitary gland stores and releases ADH and Oxytocin
False (this is the posterior pituitary gland)
What are the symptoms of hypothalamus related disorders?
Dehydration, infertility, weight loss
The _____________ hormone produced by the hypothalamus targets the kidney, hypothalamus (thirst center), and blood vessels
ADH
Insomnia or hypersomnia are symptoms that can be caused due to _____________ ____________ disorder
Pineal gland
T/F: The hormone produced by the pineal gland targets muscle cells
False
What are the primary targets of ADH
Brain, kidney, hypothalamus, blood vessels
T/F: The hormones produced by the hypothalamus are regulatory hormones, antidiuretic hormone (ADH), and Oxytocin
True
What is the primary target organ for Oxytocin
Breast(mammary glands), brain
Hypothyroidism can be caused by disfunction of the hypothalamus
Truie
What is not true about the hypothalamus
It is a vital part of the somatic nervous system, which contributes to involuntary bodily functions
T/F: The Oxytocin hormone is produced by the hypothalamus gland
True
Which is not a regulatory hormone produced by the hypothalamus?
ADH
T/F: Damage to the hypothalamus results in weigh gain
True
The hypothalamus produces oxytocin, antidiuretic hormone, and __________ hormones
Regulatory
Which of the following stimulates the release of growth hormone
Growth hormone-releasing hormone
Which of the following decreases the release of growth hormone
Growth hormone-inhibiting hormone
Which of the following stimulates secretion of thyroid-stimulating hormone
Thyrotropin-releasing hormone
Which of the following stimulates secretion of adrenocorticotropic hormone
Corticotropin-releasing hormone
Which of the following stimulates luteinizing and follicle-stimulating hormone
Gonadotropin-releasing hormone
Which of the following decreases the secretion of prolactin
Prolactin-inhibiting hormone
Which of the following stimulates the secretion of prolactin
Prolactin-releasing hormone
T/F: The anterior pituitary is made up of nervous tissue and connected to the hypothalamus via the hypothalamo-hypophyseal portal system
False
Which of the following is a physiological function that is mediated by a hormone released by the anterior pituitary?
None of the above
T/F: Irregular levels of FSH may lead to infertility in women only
False
What hormone disorder results from excessive growth hormone production in adults and causes bones in the hands, feet, and face to enlarge/widen
Acromegaly
Which hormone will stimulate the release of a hormone resulting in an increase in metabolic rate of cells and heat production
TSH
The hormone _________regulates mammary gland growth and breast milk production in females
Prolactin
_____is released from _____________ into the hypophyseal portal veins to simulate the ____________to release both LH and ____. LH stimulates testes to release _____________, LH also stimulates the ovaries to cause ________ once a month
GnRH, hypothalamus, anterior pituitary, FSH, testosterone, ovulation
Identify all hormones produced by the anterior pituitary gland
FSH, TSH, ACTH, GH
What would be the consequence if there is an insufficient amount of PRL released
Unable to produce milk in females
ACTH targets the _______________ to stimulate the release of_______________
Adrenal cortex, corticosteroids (cortisol)
T/F: The FSH and LH hormones primary target are the ovaries only
False
Which of the following is not a primary target or tissue of the Growth Hormone (GH)
Brain (goes to liver, muscle, and skeleton)
The anterior pituitary gland is located directly superior to the hypothalamus
False
The anterior pituitary gland secretes hormones into the blood most directly via what vessels
Secondary plexus hypothalamo-hypophyseal portal system
Jonathan is a 20-year-old male who is suffering from hypothyroidism. However, upon examination by a physician, it is determined that his thyroid looks normal, and he maintains a nutritious diet. A defect in which of the following structures may be a cause of Jonathan’s condition?
Anterior pituitary gland
Lucy is a new mother who is having a hard time feeding her newborn son. Despite her child having no issue with latching, no milk is coming out when he tries to feed. A lack of which of the following hormones produced by the anterior pituitary gland is most likely to be responsible for this problem?
a. Follicle-stimulating hormone (FSH)
Prolactin
T/F: The anterior pituitary gland is located in the hypothalamus
False
Which hormone stimulates the growth and development of ovarian follicles in females
Follicle stimulating hormone
What are the hormones secreted by the anterior pituitary gland
FSH, GH, LH, PRL
T/F : The anterior pituitary gland is the larger lobe of the two, however, it secretes less hormones than the posterior pituitary gland
False
The prolactin hormone of the anterior pituitary gland regulates mammary gland growth.
True
The __________ hormone within the anterior pituitary gland controls testosterone synthesis within the testes
Luteinizing
Hormones that target liver, fat, muscle, and bone
GH, IGF
GH, FSH, and LH are secreted from the ____________, while TRH, CRH, and GnRH are secreted from the ______________
Anterior, hypothalamus
List all hormones that are synthesized and released by the anterior pituitary gland
TSH, PRL, FSH, LH, ACTH, and GH
T/F: The Luteinizing Hormone controls development of sperm in the testes.
False (follicle stimulating)
Function of ACTH
stimulates adrenal cortex to release corticosteroids
What hormones are released by the pituitary gland that end up at the gonads?
FSH, LH
What is the most common cause of Acromegaly
Tumor on pituitary gland
Cushing’s syndrome occurs when a pituitary tumor produces excessive amount of a hormone called:
ACTH
All of the different types of hormones the anterior pituitary can produce are luteinizing hormone, follicle-stimulating hormone, growth hormone, adrenocorticotropic hormone, prolactin, and ________________________
TSH
What hormone is involved in Cushings Disease
ACTH
Which hormone produced controls the development of both oocyte and ovaries; controls the development of sperm within the testes
FSH
What two hormones of the Anterior Pituitary Gland target the Ovaries and Testis
FSH, LH
All are organs that are target organs for Growth Hormone EXCEPT
All cells
T/F: ACTH deficiency is caused by the lack of the TSH hormone
False
The hypothalamus is in constant communication with the ________________________ to release hormones. One of the hormones produced by this gland is named ________________ which stimulates the thyroid gland to release hormones to increase the metabolic rate
Pituitary gland, TSH
The growth hormone works synergistically with what other hormone
IGF
T/F: Cortisol is a glucocorticoid hormone released by the pancreas as a
response to stress and low blood sugar
False
T/F: True/false- The follicle-Stimulating Hormone stimulates the development of Sperm and oocyte
True
How many hormones are produced from the anterior pituitary gland and what are they
6
TSH, ACTH< PRL< GH< FSH< LH
Insufficient secretion of thyroid stimulating hormone can lead to insufficient levels of thyroid hormone causing
Hypothyroidism
The adrenocorticotropic hormone (ACTH) is produced by the _____ and releases _____ from the adrenal cortex
Anterior pituitary, corticosteroids
What structures does Luteinizing hormone (LH) target
Ovaries, testes
T/F: The posterior pituitary synthesizes ADH and oxytocin, to then be stored and released from the hypothalamus
False
What is true of ADH
Vasopressin, stimulates kidney to decrease urine output, in high doses can act as a vasoconstrictor, targets the kidney
_______ of ADH prevents the kidneys from reabsorbing more water, so it is released in your urine.
Hyposecretion- blood diluted, urine concentrated
ADH is a vasoconstrictor (vasopressin). A person with excessive vasopressin (syndrome of inappropriate Antidiuretic hormone) will have symptoms of
Muscle cramps, nausea, headaches, seizures
T/F: Antidiuretic hormones are released due to decrease in blood concentrations
False
What hormone stimulates the kidneys to reabsorb more water?
ADH
___________ hormone is associated with both SIADH and Diabetes Insipidus in Children
ADH
T/F: Oxytocin targets only the brain
False
T/F: Growth Hormones stimulates the liver to release insulin growth factors
True
T/F: The hypothalamus and anterior pituitary gland are connected by the hypothalamo-hypophyseal portal system, which is used to transport hormones from the hypothalamus to the anterior pituitary gland
True
Hypersecretion of growth hormone can lead to a condition called __________. While hyposecretion can lead to a disorder called _____________
Gigantism, dwarfism
What type of muscle does oxytocin help contract in the uterus
Smooth muscle
Function of oxytocin
Eject milk, emotional feelings of bonding
T/F: ADH and oxytocin are transported to the posterior pituitary gland through the hypothalamo-hypophyseal tract
True
ADH and oxytocin are produced in the
Hypothalamus
T/F: The posterior pituitary gland is attached to the corpus callosum, via nerves and blood vessels
False
The term hypothalamo-hypophyseal tract refers to a connection between which two endocrine structures
Hypothalamus and Posterior pituitary
A patient has been experiencing a lot of weight gain in their mid section and their face has also gotten noticeably rounder. The patient was confused because they were losing weight in their arms and legs while gaining weight in other areas. They were also bruising a lot easier than normal. When going in to see what was going on, the doctor found that there was a pituitary tumor that was producing excessive amounts of ACTH causing all of these problems. What disorder is this patient experiencing
Cushing syndrome
When dehydrated, antidiuretic hormone stimulates the kidneys to increase/decrease the urine output and the thirst center to increase/decrease fluid intake
Decrease, increase
Diabetes insipidus, a disorder characterized by the need to urinate frequently, is caused by the lack of the hormone, ________________
ADH
The pineal gland produces _____________ , which targets the __________ to regulate the circadian rhythm and function in sexual maturation
Melanoma, brain
Excessive _____ can delay the onset of puberty
Melatonin
Pineal gland characteristics
Secretes the hormone melatonin
Is involved in the regulation of the sleep-wake cycle (circadian rhythm)
Sensitive to light and darkness
Which of the following is not a function of the parathyroid gland?
Decrease blood calcium levels
Which of the following cells produces calcitonin and PTH
C cells, follicle cells
T/F: Hyperthyroidism is characterized by a high level of T-4 and a low level of TSH
True
T/F: Cretinism is disease that is characterized by stunted physical and mental growth due to hyperthyroidism
False
T/F: Hypothyroidism causes an increase in the production of TH
False
T/F: A goiter is an enlargement of the thyroid usually due to an insufficient amount of iodine
True
Hormones produced by the thyroid gland
T3, T4, calcitonin
Which hormone is NOT matched with its correct function and releasing location
Thyrotropin Releasing Hormone –> activates thyroid gland, produced by the anterior pituitary
End on: match each thyroid disorder with the statement that best describes it