Endocrine Secretion from the Gut Flashcards
Where are G cells located?
In the pylori antrum of the stomach
What do G cells secrete?
gastrin
What does gastrin do?
Stimulates gastric motility
Gastrin stimulates parietal cells to secrete what?
HCl
What cells secrete Somatostatin?
D cells in stomach
Delta islet cells in pancreas
What does Somatostatin do?
Decreases pancreatic secretion
Somatostatin inhibits the effect of what?
Gastric acid secretion and gallbladder contraction
CCK is secreted from what cells?
I cells in the SI
What causes CCK to be secreted?
Presence of fat in the duodenum
What does CCK do to the gallbladder?
Stimulates contraction and release of bile
CCK relaxes what?
Sphincter of Oddi and the lower (cardiac) sphincter
CCK inhibits what?
Gastric emptying
CCK also stimulates what from pancreas?
Pancreatic enzyme secretion
Secretin is secreted by what cells?
S cells in the intestinal crypts of Lieberkuhn
What does secretin do?
Stimulates the release of bicarbonate from the pancreass
What does secretin decrease?
Decreases gastric acid secretion
Gastric inhibitory peptide is secreted by what cells?
K cells in the SI
GIP inhibits what?
Effect of gastrin on the parietal cells in the stomach
What endocrine secretion resembles Glucagon?
Glucagon-like peptide
Glucagon-like peptide is secreted by what cells?
K cells in the duodenum AND jejunum
Grehlin is secreted by what cells?
P cells in the stomach
Grehlin is increased when? Decreased when?
Increased before meals
Decreased after meals
Motilin is secreted by what cells?
M cells in the duodenum
What does motilin control?
Cyclical movement of the gut
Motilin is increased in what state?
Increased in the fasting state
