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Pharmacology and Drug Dosage Cals > Endocrine Pharmacology > Flashcards

Endocrine Pharmacology Flashcards

1
Q

Corticosteroids are naturally secreted by this part of the adrenal gland.

A

Adrenal cortex

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2
Q

What drugs are used to treat addison’s disease?

A

Mineralcorticoids

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3
Q

Medrol is an example of what drug classification?

A

Glucocorticoids.

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4
Q

What classification of endocrine drugs can cause electrolyte imbalance and hyperglycemia?

A

Glucocorticoids

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5
Q

Gucocorticoids act to suppress what body system?

A

The immune system

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6
Q

That hormones does the thyroid produce to regulate metabolism?

A

T3 and T4

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7
Q

Name an example of a thyroid replacement hormone

A

Levothyroxine (Synthroid)

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8
Q

The dosage of these hormones is adjusted by the clients’s labwork

A

Thryoid replacement hormones

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9
Q

What condition results from an increase in thyroid hormone production and secretion?

A

Hyperthyroidism

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10
Q

What medication blocks synthesis of T3 and T4 but does not destroy already existing T3 and T4?

A

Antithyroid medications

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11
Q

Exubera is an example of what type of insulin?

A

Inhaled insulin powder

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12
Q

What is Type I diabetes

A

Insufficient insulin produced by the beta cells in the pancreas

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13
Q

What insulin has an onset of 10 minutes and results in a rapid reduction of glucose levels

A

Lispro (Humalog)

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14
Q

What insulin is the only insulin that can be given IV?

A

Regular Insulin

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15
Q

What type of insulin have an onset of 2-4 hours and a peak of 6-12 hours?

A

Intermediate acting insulins

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16
Q

Which classification of drugs is the oldest oral agent given to diabetics

A

Sulfonylureas

17
Q

Which classification of diabetes drugs delay the absorption of carbohydrates from the small intestines?

A

Alpha Glucosidase Inhibitors

18
Q

Name 2 examples of Meglitinide Oral Hypoglycemic agents

A

Starlix and Prandin

19
Q

What hormone breaks down stored glycogen to glucose resulting in elevated blood glucose levels?

A

Glucogon

20
Q

What drug requires insulin to be present for it to be used?

A

Metformin (Glucophage) which is a biguanide - Reduces hepatic glucose production - Does not cause hypoglycemia.

21
Q

What classification of diabetes drugs should not be used with DKA?

A

Meglitinide Oral Hypoglycemic agents

22
Q

What diabetes medication class works to enhance insulin receptor site sensitivity without increasing insulin secretion?

A

Thiazolidinediones (Avandia)

23
Q

What classification of drugs supress glucagon and delay gastric emptying/?

A

Amylinomimetic Agents and Incretin Mimetic Agents

24
Q

What drug must be held when a patient has a diagnostic test using iodine dye as lactic acidosis can occur?

A

Glucophage (metformin) - Biguanide class

25
Q

What insulin has a peak of 2-3 hours and a duration of 4-6 hours?

A

Regular Insulin

26
Q

What type of insulin has an onset of 1 hour, no appreciable peak and lasts 24 hours

A

Lantus Insulin

27
Q

Can mineralcorticoids lead to physical dependency?

A

No - They maintain BP, restore Fluid and electrolyte imbalance and may mask the symptoms of infection

28
Q

Why is it important to know what an insulin will peak?

A

It is the time the patient is most likely to experience a hypoglycemic episode.

29
Q

Do glucocorticoids cure disease?

A

No, they relieve symptoms of tissue inflammation.

30
Q

Are nervousness and weight loss side effects of thyroid replacement hormones?

A

Yes!

31
Q

Can glucocorticoids be stopped abruptly?

A

NO! they must be tapered as the adrenal cortex will decrease the body’s production of corticoids after long term use

32
Q

What are the contraindications for Starlix (Meglinitide Oral Hypoglycemic agent)

A

Liver Dysfunction, DKA, Pregnancy/lactation/.children

33
Q

What is PTU (Propylthioracil) used for

A

Treats hyperthyroidism by blocking synthesis of T3 and T4. Another drug in this class is Methimazole (Tapazole)

34
Q

What is Medrol?

A

A glucocorticoid

Pharmacology and Drug Dosage Cals (4 decks)

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