Endocrine Pharmacology Flashcards

1
Q

Corticosteroids are naturally secreted by this part of the adrenal gland.

A

Adrenal cortex

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2
Q

What drugs are used to treat addison’s disease?

A

Mineralcorticoids

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3
Q

Medrol is an example of what drug classification?

A

Glucocorticoids.

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4
Q

What classification of endocrine drugs can cause electrolyte imbalance and hyperglycemia?

A

Glucocorticoids

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5
Q

Gucocorticoids act to suppress what body system?

A

The immune system

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6
Q

That hormones does the thyroid produce to regulate metabolism?

A

T3 and T4

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7
Q

Name an example of a thyroid replacement hormone

A

Levothyroxine (Synthroid)

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8
Q

The dosage of these hormones is adjusted by the clients’s labwork

A

Thryoid replacement hormones

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9
Q

What condition results from an increase in thyroid hormone production and secretion?

A

Hyperthyroidism

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10
Q

What medication blocks synthesis of T3 and T4 but does not destroy already existing T3 and T4?

A

Antithyroid medications

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11
Q

Exubera is an example of what type of insulin?

A

Inhaled insulin powder

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12
Q

What is Type I diabetes

A

Insufficient insulin produced by the beta cells in the pancreas

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13
Q

What insulin has an onset of 10 minutes and results in a rapid reduction of glucose levels

A

Lispro (Humalog)

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14
Q

What insulin is the only insulin that can be given IV?

A

Regular Insulin

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15
Q

What type of insulin have an onset of 2-4 hours and a peak of 6-12 hours?

A

Intermediate acting insulins

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16
Q

Which classification of drugs is the oldest oral agent given to diabetics

A

Sulfonylureas

17
Q

Which classification of diabetes drugs delay the absorption of carbohydrates from the small intestines?

A

Alpha Glucosidase Inhibitors

18
Q

Name 2 examples of Meglitinide Oral Hypoglycemic agents

A

Starlix and Prandin

19
Q

What hormone breaks down stored glycogen to glucose resulting in elevated blood glucose levels?

20
Q

What drug requires insulin to be present for it to be used?

A

Metformin (Glucophage) which is a biguanide - Reduces hepatic glucose production - Does not cause hypoglycemia.

21
Q

What classification of diabetes drugs should not be used with DKA?

A

Meglitinide Oral Hypoglycemic agents

22
Q

What diabetes medication class works to enhance insulin receptor site sensitivity without increasing insulin secretion?

A

Thiazolidinediones (Avandia)

23
Q

What classification of drugs supress glucagon and delay gastric emptying/?

A

Amylinomimetic Agents and Incretin Mimetic Agents

24
Q

What drug must be held when a patient has a diagnostic test using iodine dye as lactic acidosis can occur?

A

Glucophage (metformin) - Biguanide class

25
What insulin has a peak of 2-3 hours and a duration of 4-6 hours?
Regular Insulin
26
What type of insulin has an onset of 1 hour, no appreciable peak and lasts 24 hours
Lantus Insulin
27
Can mineralcorticoids lead to physical dependency?
No - They maintain BP, restore Fluid and electrolyte imbalance and may mask the symptoms of infection
28
Why is it important to know what an insulin will peak?
It is the time the patient is most likely to experience a hypoglycemic episode.
29
Do glucocorticoids cure disease?
No, they relieve symptoms of tissue inflammation.
30
Are nervousness and weight loss side effects of thyroid replacement hormones?
Yes!
31
Can glucocorticoids be stopped abruptly?
NO! they must be tapered as the adrenal cortex will decrease the body's production of corticoids after long term use
32
What are the contraindications for Starlix (Meglinitide Oral Hypoglycemic agent)
Liver Dysfunction, DKA, Pregnancy/lactation/.children
33
What is PTU (Propylthioracil) used for
Treats hyperthyroidism by blocking synthesis of T3 and T4. Another drug in this class is Methimazole (Tapazole)
34
What is Medrol?
A glucocorticoid