Endocrine pharmacology Flashcards
adverse effects of corticosteroids
cushing's syndrome peptic ulceration hyperlipidaemia fluid retention pancreatitis glaucoma weight gain depression insomnia
how is metformin taken?
orally
adverse effects of carbimazole
hypothyroidism
what is metformin?
first line treatment for T2DM
what are side effects of metformin?
GI upset
lactic acidosis
adverse effects of sulfonylureas
hepatotoxicity
hypoglycaemia
weight gain
hyponatraemia
how are GLP-1 agonists (-tides) taken?
subcutaneously
how are sulfonyureas taken?
orally
what are side effects of GLP-1 agonists (-tides)
causes weight loss
nausea
vomiting
increased risk of pancreatitis
what is the mechanism of sulfonlureas?
increases pancreatic insulin secretions
how do GLP-1 agonists (-tides) work?
incretin mimetic which inhibits glucagon secretion
what are the side effects of SGLT-2 inhibitors (-gliflozins)?
weight loss
what are examples of sulfonylureas?
gliclazide and glimepiride
