Endocrine Pharm Flashcards

1
Q

Linagliptin, Saxagliptin, Sitagliptin Class? MOA?

A

DPP4

Increase insulin and decrease glucagon release

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Gliptin’s AE?

A

Infections

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Pramlintide MOA?

A

Decreases gastric emptying and glucagon release

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Canagliflozin MOA?

A

MOA: Blocks SGLT-2 inhibitor=>blocks reabsorption of glucose in PCT

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Acarbose/Miglitol

A

MOA: Inhibits intestinal brush-border alpha-glucosidases=>delay glucose absorption

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Glitazones/Thiazolidinediones MOA

A

MOA: Increase Insulin sensitivity and binds to PPAR-gamma nuclear transcription factor=>increase insulin sensitivity and adiponectin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly