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RUSVM Physiology II > Endocrine Pancreas Review Questions (Vieira) > Flashcards

Endocrine Pancreas Review Questions (Vieira) Flashcards

1
Q

Which cells are responsible for the production of Glucagon?

A

Alpha Cells

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2
Q 
Which of the following is an inhibitor of secretion?
A. Glucose
B. Amino Acids
C. Fatty Acids
D. Somatostatin
A

D. Somatostatin

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3
Q

Which glucose transporter is insulin sensitive?

A

GLUT4

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4
Q

Which glucose transporter is important for the glucose entrance in the beta cell?

A

GLUT2

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5
Q

T/F The acute phase of insulin secretion involves the synthesis of new insulin by beta cells.

A

False.

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6
Q

What is the name of the receptor that insulin binds to?

A

Receptor Tyrosine Kinase

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7
Q 
Which of the following is a hormone released immediately after hypoglycemia?
A. Cortisol
B. Catecholamine
C. Growth Hormone
D. Somatostatin
A

B. Catecholamine

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8
Q 
Under insulin action, the liver will: 
A. Increase gluconeogenesis
B. Decrease gluconeogenesis
C. Increase glycogenolysis
D. Increase lypolysis
A

B. Decrease gluconeogenesis

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9
Q

Which of the following is NOT true about Glucagon?
A. It is a polypeptide hormone
B. Induces liver ketogenesis
C. Is stimulated by hyperglycemia
D. In carnivores it is realeased after protein ingestion

A

C. Is stimulated by hyperglycemia

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10
Q 
Which of the following is NOT true about gluconeogenesis?
A. Is made by the liver
B. Is made by the kidneys
C. Alanine and Glutamine are stubstrates
D. FFAs are a substrate
A

D. FFAs are a substrate

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11
Q 
Which enzyme is responsible for the release of FFAs and glycerol  in the blood during diabetes?
A. Hormone-Sensitive Lipase
B. Hormone-Sensitive Amylase
C. Hormone-Sensitive Phosphate
D. Hormone-Sensitive Anhydrase
A

A. Hormone-Sensitive Lipase

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12
Q

Which of the following is NOT true regarding Type I Diabetes?
A. Is more common in dogs
B. Is caused by a relative insulin deficiency
C. Hyperglycemia is a consequence of decreased glucose uptake
D. Cataracts are a possible complicaton

A

B. Is caused by a relative insulin deficiency

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13
Q

Which of the following is NOT true about Diabetes Mellitus Hyperglycemia?
A. Is a consequence of decreased glucose uptake in the muscle
B. Is a consequence of decreased glucose uptake in the adipose tissue
C. Is a consequence of increased gluconeogenesis
D. Is a consequence of glycogenesis

A

D. Is a consequence of glycogenesis

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14
Q

Which hormone produced by the beta cells can aggregate causing irreversible beta cell damage in cats?

A

Amylin

Amylin aggregates and forms the amyloid. Amyloid depostion in pancreatic islets leads to amyloidosis

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15
Q

T/F During the early stages of insulin resistance beta cells increase insulin production

A

True

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16
Q

Which of the following is NOT true about the pathophysiology of Type 2 Diabetes?
A. Increased production of insulin perpetuates amyloidosis
B. Decreased production of insulin perpetuates amyloidosis
C. Glucotoxicity is a reversible damage
D. Obesity decreases insulin sensitivity

A

B. Decreased production of insulin perpetuates amyloidosis

17
Q 
Which of the following is NOT a ketone body?
A. Acetoaccetate
B. Beta hydroxybutyrate
C. Sorbitol
D. Acetone
A

C. Sorbitol

18
Q 
Which of the following is NOT true regarding ketone bodies?
A. Production is stimulated by glucagon
B. Renal threshold is high 
C. Decrease the [H+] in the blood
D. Are source of energy for the brain
A

C. Decrease the [H+] in the blood

19
Q 
Which of the following is NOT expected in a patient with DKA?
A. Decreased pH
B. Decreased HCO3
C. Normal Anion Gap
D. Increased pCO2
A

C. Normal anion gap

20
Q 
Why is hyperventilation present in DKA?
A. To increase pCO2
B. To decrease pCO2
C. To decrease pH
D. To increase [H+]
A

B. To decrease pCO2

21
Q 
Which of the following does NOT contribute to the hypokalemia in DKA?
A. Increased secretion of aldosterone
B. Osmotic diuresis
C. Acidosis
D. Hypovolemia
A

D. Hypovolemia

22
Q 
Which of the following hormones is considered the most ketogenic?
A. Epinephrine
B. Glucagon
C. Cortisol
D. GH
A

B. Glucagon

23
Q

T/F For the synthesis of ketone bodies to be enhanced there must be and increased mobilization of Free Fatty Acids.

A

True

24
Q 
The increase in ketone bodies without interference in the blood pH is called: 
A. Ketonuria
B. Ketogenesis
C. Ketosis
D. Ketoacidosis
A

C. Ketosis

RUSVM Physiology II (3 decks)

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