Endocrine Pancreas Disorders

Question 1

α cells secrete ___ & action.

Answer 1

Glucagon

↑ blood glucose by glycogenolysis in liver

Question 2

β cells secrete ___ & action.

Answer 2

Insulin

↓ blood glucose by tissue uptake

Question 3

δ cells secrete ___ & action.

Answer 3

Somatostatin

suppress insulin & glucagon release

Question 4

Diagnostic criteria of diabetes

Answer 4

Random blood glucose > 200 mg/dL

Fasting blood glucose > 126 mg/dL

OGTT > 200 mg/dL

HbA1c (glycated hemoglobin) > 6.5%

Question 5

Characteristic features of Whipple’s Triad (insulinoma)

Answer 5

1. Fasting blood glucose < 50 mg/dL
2. Symptoms of hypoglycemia (confusion, weakness, fatigue)
3. Sx relief w/ glucose

Question 6

Insulinoma