Endocrine - Online MedEd - MEN syndromes

Question 1

MEN syndromes are easy to spot

3 syndromes

Answer 1

MEN 1
MEN 2a
MEN 2b

Question 2

MEN1 - what is it?

Answer 2

Humours of the hard P organs:
Pituitary - functioning or non
Parathyroid - hyperparathyroidism - hypercalcemia
Pancreas - zolinger ellison/insulinoma
-Zollinger ellison - refractory ulcers
-Insulinoma - hypoglycaemia/C peptide (high if endogenous –> secretagogue screen)

Question 3

MEN1 - genetic disorder of what?

Answer 3

MEN gene

Question 4

MEN 2a/2b - genetic disorder of what?

Answer 4

RET oncogene

Question 5

MEN2a/2b - what is it?

Answer 5

Pheo - both
Medullary thyroid cancer - both
One other thing:
1) MEN2a - parathyroid
2) MEN2b - neuronal tumours