Endocrine II Flashcards

1
Q

How do you diagnosis DM

A

Fasting plasma glucose level of 126 mg per dL or greater

A1C level of 6.5% or greater

A random plasma glucose level of 200 mg per dL or greater

A1C > 5.7 impaired glucose tolerance

a 75-g two-hour oral glucose tolerance test with a plasma glucose level of 200 mg per dLor greater

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2
Q

consequences of DM

A

Sequelae/consequences:
Frequent infections (urinary tract, vaginal (yeast), skin (yeast, cellulitis))
Retinopathy => blindness
Nephropathy => kidney failure
Neuropathy of feet and hands => ulceration/infection/gangrene/loss of limb, increase in falls.
Vascular changes => increase in cardiovascular events (MIs, strokes) and peripheral vascular disease & poorly healing wounds -> infection/gangrene/loss of limb.

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3
Q

Skin PE finding in DM

A

acanthosis nigracans

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4
Q

steps in a DM foot exam

A
  1. Check for skin lesions/ infection, etc (don’t forget to check between the toes
  2. Pressure sensation using Monofilament testing
  3. Vibration sensation using tuning fork
  4. Superficial pain using pinprick/ temperature sensation
  5. Reflexes
  6. Pulses
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5
Q

describe diabetic peripheral neuropathy

A

Diabetic Peripheral neuropathy
Affects 30% of patients with DM, caused by damaged to the peripheral nerves due to poorly controlled blood sugar

Stocking and glove pattern

Presentations: burning, paresthesia and/or numbness, usually distal limb, symmetric polyneuropathy

Complications:
Infection, ulcer formation and injury can go unnoticed due to the paresthesia/ numbness.
Amputation (toes, foot, maybe even limb)
Treatment: Good control of blood sugar (ideally A1C <6.5), perform self foot exam routinely, anti-neuropathy medication

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6
Q

what should be included within in a SOAP note for a DM foot exam

A

Diabetic foot exam
– No lesions, callus on examination of feet, toes, between toes
– Dorsalis pedis pulse +2
– Vibratory sense intact bilaterally
– decrease sensation to monofilament in left lateral foot, right great toe vs Sensation intact to monofilament.

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7
Q

what are the four important components of metabolic syndrome?

A
Also known as Syndrome X or Insulin Resistance Syndrome Consists of
– Abdominal obesity
– Insulin resistance
– Elevated blood pressure
– Lipid abnormalities

Prevalence increases with age and increasing body weight

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8
Q

what needs to included within the workup of metabolic disease?

A

• Workup:
– Good past medical and family history (specifically hx of cardiac disease or DM)
– History of weight changes
– Lifestyle (i.e. sedentary, eating habits) ***

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9
Q

what does the physician need to ask the patient to do to have a good medication assessment?

A

• Have patient bring in all medications and supplement to doctors visit, “brown bag check”
• Ask “What prescription medications, over the counter medicines, vitamins, herbs, or supplements do you use?”
• Review medications during every visit
• Use Beer’s Criteria or other medication clinical tools to reduce or avoid prescribing
medication that can lead to adverse events
• “Start low, go slow” (start certain medications at lowest dose and increase slowly for older patients)
• Close followup after starting new medication

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10
Q

what is functional ability?

A

Ability of this patient to perform daily task for living there normal life also known as activities of daily living (ADL)
Activities of daily living (ADL)
– Self care: eating, dressing, bathing, transferring between the bed and a chair, using the toilet, controlling bladder and bowel functions (consider effort needed to button or unbutton short, wear shoes, climb up
on bed)
– Living independently: doing housework, preparing meals, taking medications properly, managing finances, using a telephone

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11
Q

what are Activities of daily living (ADL)?

A

Activities of daily living (ADL)
– Self care: eating, dressing, bathing, transferring between the bed and a chair, using the toilet, controlling bladder and bowel functions (consider effort needed to button or unbutton short, wear shoes, climb up
on bed)
– Living independently: doing housework, preparing meals, taking medications properly, managing finances, using a telephone

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12
Q

how should vision be assessed for older patients?

A

Vision Assessment:
• No specific recommendation even through the USPSTF
• Periodic assessment with Snellen Eye Chart
• Ophthalmologist referral to monitor diabetic patient for diabetic retinopathy
• Ophthalmologist referral for patient with increased risk for glaucoma i.e. family history, etc
• Remember many older patients continue to drive well into their 80s and sometimes even into their 90s, consider assessing vision for driving safety

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13
Q

what is important to know about falls in the elderly?

A

falls are multifactorial!

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14
Q

what does a PE testing cognition entail?

A
Neurologic physical exam including
– Mental status i.e. orientation , screening tools
– Cranial nerves including vision screen
– Cerebellar status / motor system i.e. gait, Romberg, finger to nose, heel to shin
– Strength
– Sensation
– Reflexes
– Other i.e. Babinski, etc
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15
Q

what is the most common cause of hearing loss in older adults?

A

Presbycusis or age related sensorineural hearing loss is most common hearing condition in older patients.
Progressive symmetric loss of high frequency hearing
• Clinical presentation: progressive hearing loss along with tinnitus (ringing in the ears), vertigo and feeling off balance (increases patient risk for falls)
• Cause: loss of cochlear hair cells and ganglion cells in the vestibulocochlear nerve. Consider reviewing medication list for ototoxicity.
• Workup: otoscopic examination, Audioscope examination, and the whispered voice test
• USPSTF recommends asking patients about their hearing but there is no guideline for asymptomatic patients
• Treatment: Hearing aids, auditory rehabilitation, cochlear implantation

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16
Q

what are three different kinds of urinary incontinence?

A

Urinary Incontinence
• Stress incontinence
– Involuntary leakage of urine that occurs with increases in intra-abdominal pressure (i.e. w/ exertion,
sneezing, coughing, laughing)
• Urge incontinence
– Detrusor muscle overactivity, leading to uninhibited (involuntary) detrusor muscle contractions during bladder filling
• Overflow incontinence
– Continuous urine leakage due to incomplete bladder emptying
– Detrusor muscle underactivity or bladder outlet obstruction
• Other factors
– Mixed Incontinence – Stress and urge Incontinence
– UTI, DM, constipation,

17
Q

patients 65 and older need to be up to date on the following vaccines:

A

• Make sure patient 65 and older are up to date on the following vaccine
– Tetanus or tetanus with pertussis vaccine
– Influenza vaccine
– Pneumococcal vaccine
– Herpes zoster vaccine

18
Q

what are the two key questions to assess for depression in the elderly?

A

• As patient become older, more frail, unable to perform ADLs, inability to drive, loss of spouse or partner can lead to risk of social isolation
• This social isolation can lead to depression
• Depression can be difficult to diagnose in older patients as the symptoms in old individuals can
mimic cognitive and functional decline
• For these reasons and others depression is underdiagnosed in the elderly and may go untreated
• A method to capture these patient is by asking two specific questions to every patient in every office visit
– “During the past month, have you been bothered by feeling down, depressed, or hopeless?”
– “During the past month, have you been bothered by little interest or pleasure in doing
things?”
– “yes” to these questions prompts a more detailed questionnaire
• Patient Health Questionnaire-9 (PHQ-9) – this can start the conversation about depression