Endocrine Glands and hormones Flashcards

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1
Q

Homeostasis

A

the maintenance of a relatively constant internal environment despite fluctuations in the external environment.

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2
Q

List of endocrine glands (12)

A

pineal gland
Hypothalamus
pituitary gland
thyroid gland
Parathyroid gland
thymus
Adrenal gland
kidneys
pancreas
ovaries
uterus
Testes

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3
Q

exocrine gland

A

Gland that secretes into a duct that carries the secretion to the surface of the body cavities

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4
Q

endocrine gland

A

Secrete hormones into the extracellular fluid that surrounds the cells that make up the gland
secretion then usually passes into the capillaries to be transported by the blood
Sometimes called ductless gland

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5
Q

hormones

A

Chemicals secreted by endocrine system and transported in bloodstream.
changes the function of cells by activating certain genes in nucleus so a particular enzyme or protein is produced.

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6
Q

Hormone receptor

A

each type of receptor will bind wt only one specific molecule

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7
Q

Saturation

A

once all receptor molecules are occupied by hormone molecules, the addition of more hormones does not produce any greater effect.

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8
Q

Negative feedback loop

A

feedback that reduces the effect of, or eliminates, the original stimulus.
Body responds to a change (stimulus) -> new hormone made -> circulates -> back to original endocrine gland -> stops sending out anymore.

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9
Q

pancreas

A

Both endo and exo
exo - amylase, protease, lipase (pancreatic enzymes)
Endo - insulin and glucagon

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10
Q

lock and key model

A

Hormone will only work on a part of the body if it ‘fits’
if hormone binds to receptor on cell membrane, hormone can have effect.
Cells with no specific receptors can’t be affected by certain hormones.

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11
Q

3 types of hormones

A

Protein
Steroid
Amine

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12
Q

Protein

A

Those secreted by the pituitary gland and pancreas

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13
Q

steroid

A

Made from cholesterol, an important lipid.
secreted by gonads and adrenal cortex

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14
Q

Amine

A

made of small amino acid molecules

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15
Q

Hormone pathway into cell - protein and amine hormones

A

are water soluble.
Attach to receptor proteins on cell membrane of target cell. This triggers a secondary messenger called cyclic AMP (cAMP) in cytoplasm to activate enzymes to alter cell metabolism.
cAMP may move through cell, activating genes and causing a change in the cells function.
Quick to cause a response, but effect short lasting.

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16
Q

enzymes

A

Are proteins that increase speed of reactions ‘organic catalyst’
enzymes adjust chemical activity of cells, the speed of reactions will either increase or decrease

17
Q

Hormone pathway into cell - steroid hormones

A

lipid/fat soluble, can diffuse through cell membrane through lipid bilayer.

18
Q

Water soluble hormones (Protein/amine)

A

Hormones made from pituitary and pancreas

19
Q

lipid soluble hormones (Steroids)

A

Hormones made by gonads and adrenal cortex

20
Q

hypothalamus

A

Controls the pituitary gland and is attached to it by the infundibulum
secretes factors: releasing factors (rf) - stimulates secretions, inhibiting factors (if) - slows down secretion
Factors flow through blood vessels to reach anterior lobe of pituitary gland, whereas for posterior lobe of pituitary gland, hormones pass through nerve fibres in the infundibulum from the hypothalamus.

21
Q

pituitary gland

A

“The master” gland because it regulates the functions of the other endocrine glands and many body functions.
Factors travel down through blood vessels to the anterior lobe.
other hormones are made by the hypothalamus and pass along nerve fibres to the posterior lobe where they are released.

22
Q

Anterior pituitary hormones (6)

A

Growth hormone (GH)
Thyroid stimulating hormone (TSH)
Adenocorticotropic hormone (ACTH)
Prolactin (PRL)
Follicle stimulating hormone (FSH)
Luteinising hormone (LH)

23
Q

Posterior pituitary hormones (2)

A

Antidoretic Hormone (AH)
Oxytocin (OT)

24
Q

Growth hormone (GH)

A

Target - all cells
effect - promotes body growth, bone and muscle, protein synthesis. Maintains size of body organs through life.

25
Q

Thyroid stimulating hormone (TSH)

A

Target - thyroid gland
effect - stimulates the production and release of thyroid hormones (TSH)

26
Q

Adenocorticotropic Hormone (ACTH)

A

Target - adrenal gland
effect - controls production and release of aldosterone and cortisol (corticosteroids)

27
Q

Prolactin (PRL)

A

target - mammary glands
Effect - breast development and stimulates milk production

28
Q

Follicle stimulating hormone (FSH)

A

Target - ovary/testes
effect - stimulates the growth of the Graafian follicle and maturation of the ova or the development of seminiferous tubules and maintenance of spermatogenesis.

29
Q

Luteinising hormone (LH)

A

target - ovary/testes
Effect - induces ovulation and stimulates the formation of the corpus luteum. In males stimulates interstitial cells in testes to produce testosterone.

30
Q

antidiuretic hormone (AH)

A

Target - kidney tubules
effect - reabsorption of water from urine at the tubule, return water to blood and hence decreasing urine

31
Q

Oxytocin (OT)

A

target - uterus wall
Effect - stimulates the contraction of the smooth muscles of the uterus wall during the birth process (labour). It also causes the ejection of milk from the mammary glands.

32
Q

pineal gland

A

Size of pea, decreases in size after puberty
secretes melatonin which is stimulated by darkness and inhibited by light.

33
Q

Cortisol

A

promotes normal metabolism
During stress, glucogenesis and increased blood glucose
helps body fight the effects of short term stress.