Endocrine Drugs Flashcards
The three chemical substance, known as HORMONE, in the body that regulates and control the activity of certain cells or organs.
- Peptide hormones
- Steroid hormones
- Amine hormones
A hormone that cannot be given orally because of proteolytic enzymes in the GIT.
Peptide hormone
Growth hormone inhibiting hormone (GHIH) that has adverse effects of GI distress, constipation/diarrhea, flatulence, nausea, acute cholecystitis.
Somatostatin Agonists
The three CORTICOID drugs acting on the adrenal cortex.
- Glucocorticoid
- Mineralocorticoid
- Gonadocorticoid
This impair the ability of phagocytes and block production of antibodies.
Immunisuppressive
It blocks arachidonic acid.
Anti-Inflammatory
This drug has pharmacologic actions that increase metabolic rate, protein synthesis, cardiac output, renal perfusion, oxygen use, body temperature, blood volume, and growth processes.
Levothyroxine
It is an Antithyroid Agents that is use to prevent formation of thyroid hormone and inhibits conversion of T4 to T3
Thioamides
A group of metabolic disorders of fat, carbohydrate, and protein metabolism that results from defects in insulin secretion, insulin action (sensivity), or both.
Diabetes mellitus
It is insulin-dependent and has an autoimmune process.
TYPE I Diabetes Mellitus
It is heredity and has a insulin level of: Low [deficiency]; high [resistance]
TYPE II Diabetes Mellitus
One of the complications of Insulin that if it occurs severe, IV glucose may be needed.
Hypoglycemia
It works by opening Ca+ channels of the beta cells stimulating release of insulin.
Sulphonylureas
An anti-diabetic drugs that decreases glucose production by the liver; increase tissue response to insulin.
Biguanides
The side effects of this anti-diabetic drugs is flatulence.
Alpha-glucosidae inhibitors