Endocrine Drugs Flashcards

1
Q

The three chemical substance, known as HORMONE, in the body that regulates and control the activity of certain cells or organs.

A
  • Peptide hormones
  • Steroid hormones
  • Amine hormones
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1
Q

A hormone that cannot be given orally because of proteolytic enzymes in the GIT.

A

Peptide hormone

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2
Q

Growth hormone inhibiting hormone (GHIH) that has adverse effects of GI distress, constipation/diarrhea, flatulence, nausea, acute cholecystitis.

A

Somatostatin Agonists

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3
Q

The three CORTICOID drugs acting on the adrenal cortex.

A
  • Glucocorticoid
  • Mineralocorticoid
  • Gonadocorticoid
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4
Q

This impair the ability of phagocytes and block production of antibodies.

A

Immunisuppressive

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5
Q

It blocks arachidonic acid.

A

Anti-Inflammatory

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6
Q

This drug has pharmacologic actions that increase metabolic rate, protein synthesis, cardiac output, renal perfusion, oxygen use, body temperature, blood volume, and growth processes.

A

Levothyroxine

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7
Q

It is an Antithyroid Agents that is use to prevent formation of thyroid hormone and inhibits conversion of T4 to T3

A

Thioamides

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7
Q

A group of metabolic disorders of fat, carbohydrate, and protein metabolism that results from defects in insulin secretion, insulin action (sensivity), or both.

A

Diabetes mellitus

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7
Q

It is insulin-dependent and has an autoimmune process.

A

TYPE I Diabetes Mellitus

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7
Q

It is heredity and has a insulin level of: Low [deficiency]; high [resistance]

A

TYPE II Diabetes Mellitus

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8
Q

One of the complications of Insulin that if it occurs severe, IV glucose may be needed.

A

Hypoglycemia

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9
Q

It works by opening Ca+ channels of the beta cells stimulating release of insulin.

A

Sulphonylureas

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10
Q

An anti-diabetic drugs that decreases glucose production by the liver; increase tissue response to insulin.

A

Biguanides

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11
Q

The side effects of this anti-diabetic drugs is flatulence.

A

Alpha-glucosidae inhibitors

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12
Q

It decrease insulin resistance, increase glucose uptake and decrease glucose production in liver.

A

Thiazolidinediones

13
Q

An anti-diabetic drugs that increases insulin release, reduces glucagon release.

A

Gliptins

14
Q

The sign and symptoms of this disorder are: irregular periods, infertility, acne, hirsutism.

A

PCOS (Polycystic Ovary Syndrome)

15
Q

It has a pharmacologic action that increases blood glucose level by increasing the breakdown of glycogen into glucose, decreasing glycogen enhances the synthesis of glucose.

A

Glucagon

16
Q

Types of Insulin

A

I. Rapid-acting
II. Short-acting
III. Intermediate-acting
IV. Long-acting