Endocrine Drugs Flashcards
Best taken 30 min prior to meal.
Glipizide
– Instruct clients to take immediate release tablets two times per day with breakfast and dinner
and to take sustained release tablets once daily with dinner.
Metformin HCl
– Instruct clients to take once a day, with or without food.
Pioglitazone
Instruct clients to take with the first bite of food, three times per day. If a dose is missed, take the
dose at the next meal but do not take two doses.
Acarbose –
Encourage clients to exercise consistently and to follow appropriate dietary
guidelines.
NURSING ADMINISTRATION
Sitagliptin
¡ Increases insulin release, reduces glucagon release
GLIPTINS
Rosiglitazone, Pioglitazone
¡ Decrease insulin resistance, increase glucose uptake and decrease glucose production in liver
¡ Causes hypoglycemia
THIAZOLIDINEDIONES
Monitor clients for signs of hypoglycemia. If abrupt onset, the client will experience SNS symptoms, such as
tachycardia, palpitations, diaphoresis, and shakiness. If gradual onset, the client will experience PNS symptoms,
such as headache, tremors, and weakness.
Hypoglycemia
– can be at room temp for up to 1 month
Vial in use
oral therapy for chronic adrenal
insufficiency
Cortisone
synthetic steroid identical to cortisol
¡ Preferred drug for adrenocortical
insufficiency
Hydrocortisone
+Defined as a persistent
systolic pressure of
greater than 140mmHg
and/or a diastolic pressure
of greater than 90mmHg
+Major risk factor for CAD,
CVD and death
HYPERTENSION
controlled by the ANS
HEART RATE
+Reduction of cardiovascular and renal
morbidity and mortality
GOAL OF
ANTIHYPERTENSIVE
THERAPY
+Drugs that accelerate the
rate of urine formation
that results to the
removal of sodium and
water from the body
Diuretics
+Indications: edema associated with heart, hepatic
or renal failure, control hypertension and
increase renal excretion of calcium
DIURETICS: LOOP
+C/I: drug allergy, severe
renal disease, pulmonary
edema, active intracranial
bleeding
+A/E: Convulsions,
thrombophlebitis and
pulmonary congestion
DIURETIC:
OSMOTIC
+C/I: drug allegy, hepatic
coma, anuria and renal failure
+A/E: hypokalemia, increase
Ca, Lipids, Glucose and uric
acid, headache, impotence
and decreased libido
DIURETICS: THIAZIDES
+Central Acting – acts on the
brain by decreasing NE
production
Clonidine, Methyldopa
+Peripheral Acting – at the
heart and blood vessels
Drugs: Alpha and Beta Blockers
assess BP, Apical pulse, respiratory
status (dry cough) and CBC
ACEI
Also known as prokaryotes which are
single-celled organisms that lack a true
nucleus and nuclear membrane
BACTERIA
Substances that inhibit bacterial growth or kill
bacteria and other microorganisms
ANTIBACTERIAL DRUGS
discovered the mold that
produced Penicillin which was the first
antibiotic to be used and marketed
Alexander Fleming
