Endocrine Communication Flashcards

1
Q

What is the endocrine system

A

Used for communication around the body

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2
Q

How does the endocrine system transport its signals

A

Uses blood circulatory system

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3
Q

What are signals released by the endocrine system called

A

Hormones

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4
Q

How many types of hormones are there in

A

2

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5
Q

What are the two types of hormones

A

1) Protein and pepetide hormones
2) Steroid hormones

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6
Q

What are examples of protein and peptide hormones

A

Adrenaline
Insulin
Glucagon

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7
Q

What are examples of steroid hormones

A

Oestrogen
Testosterone

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8
Q

Describe the characteristics of protein hormones

A

-not soluble in the phospholipid membrane
-do not enter the cell
-need to bind to the cell surface membrane and release a second messenger inside the cell

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9
Q

Describe the characteristics of steroid hormones

A

-can pass through the membrane
-enter the cell and the nucleus
-have a direct effect on the DNA in the nucleus

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10
Q

What are hormones released by

A

Endocrine glands

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11
Q

Describe endocrine glands

A

-ductless-> consist of groups of cells that release the hormone directly into the blood

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12
Q

Name the 7 main endocrine glands in the body

A

1) pituitary gland
2) thyroid gland
3) thymus
4) adrenal glands
5) pancreas
6) ovaries (females)
7) testes (males)

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13
Q

What are hormones

A

chemical messengers that travel through the blood to target organs or tissues, where they trigger specific responses.

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14
Q

Why can steroid hormones enter cells directly but peptide hormones can’t?

A

-Steroid hormones are lipid-soluble so they can dissolve in the fatty cell membrane and pass through it.
-Peptide hormones are water-soluble and can’t pass through the fatty cell membrane so they bind to receptors on the cell surface instead.

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15
Q

What does the target cell have to have for non-steroid hormones

A

-must possess a specific receptor on their plasma membrane that is complementary to the shape of the hormone

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16
Q

Why can hormones be carried in the blood without affecting every cell

A

Because the hormone will only bind to the cells with the correct specific receptor which will initiate a change in the cell

17
Q

What are non-steroid hormones known as

A

First messengers

18
Q

What are first messengers

A

Signalling molecules outside the cell that bind to the cell surface membrane and intimate an effect inside the cell

19
Q

What do first messengers usually cause

A

The release of another signalling molecule in the cell (second messenger)

20
Q

What does the second messenger do

A

Stimulate a change in the activity of the cell

21
Q

Describe the first and second messenger mechanism

A

1) the hormone (first messenger) binds to a complementary receptor on the cell surface membrane of the target cell
2) this causes the G protein to be activated
3) the G protein then activates adenyl cyclase
4) the activated adenyl cyclase then converts ATP to cAMP (cyclic AMP) which is the second messenger
5) this second messenger may act directly on another protein or initiate a cascade of enzyme-controlled reactions

22
Q

Where are the adrenal glands found

A

Just above the kidneys, one on each side of the body

23
Q

How is each gland divided

A

-the adrenal coretx (the outer)
-the adrenal medulla (the inner)

24
Q

Describe the regions of the adrenal cortex

A

1) zona glomerulosa= outermost later, secretes aldosterone
2) zone fasciculata= middle layer, secretes cortisol
3) zona reticularis= innermost layer, secretes precursors molecules that are uses to make sex hormones

25
Q

Where is the adrenal medulla found

A

In the centre of the adrenal gland

26
Q

What does the adrenal gland secrete

A

Adrenaline
Noradrenaline