Endocrine-Bone Metabolism and Management Flashcards
Where are osteoblasts located
at the surface of the bone tissue
Once the osteoblasts are stored within the matrix, it becomes
an osteocyte
where are osteoclasts located
within the calcified matrix
what cell resorbs bone by decreasing the pH which causes hydroxyapatite crystals to dissolve
osteoclasts
these cells are inhibited by estrogen
osteoclasts (in men too)
hormone that is released in response to low blood calcium to maintain calcium in a narrow range
parathyroid hormone
how does parathyroid hormone act on the kidneys
stimulate resorption of calcium
stimulated by high blood calcium concentrations
calcitonin (inhibits osteoclasts)
parathyroid hormone acts in an opposite way than
calcitonin
main source of vitamin D
sun
What is the Vitamin D that we actually use for bone metabolism
Calcitriol (the kind you get from D3 aka the sun)
necessary for growth and maturation of the skeleton. causes osteoclasts to resorb bone when levels are too high
thyroid hormone
osteoporosis affects bones with higher proportion of ____ bone
cancellous
Know the difference between t and z score
for pts with osteoporosis.