endocrine and blood Flashcards
increase GH
gigantism-C
acromegaly-A
increase TSH
Graves
decrease TSH
myxedema
cretinism- kids
increase ACTH
Cushings- moon face, hirsutism, buffalo hump
decrease ACTH
addisons- bronze skin, hypotension
tertiary stage syphilis involves vasa vasorum
syphilitc aortitis
aortic arch syndrome-occlusive thromboaortopathy
Takayasu
what inflames temporal and intracranial arteries and can cause blindness
giant cell arteritis
temporal arteritis
polyarteritis nodosa
young adults, nodular reddish swellings, narrows arteries from fibrosis
necrotizing vasculitis of lungs, kidneys and nasopharynx
Wegener’s granulomatosis
triphasic color change in raynauds
pallor
cyanosis
rubor
mucocutaneous lymph node syndrome in children with conjunctival and oral edema MI
kawasaki-death 3%
heme production disrupted, dark purple urine
porphyria
fault synthesis hemoglobin, severe anemia
thalassemia
lymph cancer associated with chromosome 8
Burkitts lymphoma
MC breast tumor
fibroadenoma
MC form of invasive breast cancer
invasive ductal carcinoma- in situ
penial cancer that is in situ stage of squamous cell carcinoma, shaft of penis
Bowen disease
autosomal recessive β-globin mutation, carrier status is in heterozygous patients, but the disease develops in homozygous patients
sickle cell anemia
sickled RBCs are prone to clotting, which is a risk for a lethal stroke or acute chest syndrome
sickle cell disease
known to affect Mediterranean patients, autosomal recessive β-globin mutation, excess of opposite globin chain damages RBCs, which results in hemolysis
B-thalassemia
Heinz bodies or bite cells
GP6D
aggressive childhood leukemia, B cell cancer age 4
acute lymphoblastic leukemia
MC adult leukemia, B cell age 60
chronic lymphocytic leukemia
B cell cancer that characteristically affects the facial bone of African children, well-known for it’s “starry sky” pattern on biopsy
Burkitts lymphoma
salt and pepper appearance with skull bone erosion
Hyperparathyroidism
aggressive cancer of marrow myeloblasts, affects adults (as all myeloid cancers do), has characteristic Auer Rods on marrow biopsy
acute myeloid leukemia
myeloid cancer of adults, quickly spreads to other organs (like the spleen), has characteristic Philadelphia chromosome, which is from a t(9:22) and produces a BCR-ABL fusion gene
chronic myelogenous leukemia
cancerous cause of too many RBCs
polycythemia vera
elevated blood pressure in the protal venous system (veins of the liver), which produces… ascites, esophageal varices, or caput medusae
portal HTN