Endocrine Anatomy & Physiology Flashcards
Gland
Group of cells that works together to produce and secrete: hormones, enzymes, and other bodily components
Exocrine gland
WITH ducts (sebaceous and sudoriferous)
Endocrine gland
WITHOUT ducts - secretes directly into the blood stream to reach the target organs
Affects metabolism, growth development, reproduction, temperature, fluid balance, and emotional response
Endocrine gland
Hormones
Chemical messenger that travels through the bloodstream to their target organ
Actions of Hormones
Increase or decrease a normal body process by affecting the target organ, which can also affect the action of other hormones significantly
Metabolic changes
Occur in response to the actions of hormones
Negative feedback
When a gland one releases a hormone, which stimulates target cells to release a second hormone, gland one slows the release of hormones as it senses the second hormone rising
Pituitary gland (hypophysis)
Called the master gland, uses negative feedback to control other endocrine glands
Pituitary gland
Works with hypothalamus and is located at a small depression in the sphenoid bone
Anterior pituitary gland (adenohypophysis)
Secretes 6 major hormones
6 major hormones of the adenohypophysis
- Somatotropin [Growth hormone (GH)]
- Adenocorticotropic hormone (ADH)
- Thyroid stimulating hormone (TSH)
4 and 5. Gonadotropic hormones - [Luteinizing hormone (LH) and
Growth hormone (GH)] - Prolactin (Causes mammary gland to produce milk)
Posterior Pituitary Gland (Neurohypophysis)
Releases 2 hormones with stimulation from hypothalamus
Hormones secreted by Neurohypophysis
Oxytocin and Antidiuretic Hormone (ADH)
Oxytocin
Promotes the release of milk and stimulates uterine contraction during labor
Antidiuretic hormone (ADH)
a.k.a. Vasopressin
Decrease the amount of urine produce, also helps raise blood pressure
Thyroid
Butterfly shape, just below the larynx, connected by isthmus
Characteristics of thyroid gland
Highly vascularized, secretes T3 and T4 hormones, needs IODINE for hormone production
Tropic hormones
Responsible for stimulating OTHER glands
T3 and T4 hormones regulates:
Growth and Development
Metabolism
Activity of nervous system
Thyroid hormones
T3, T4, and Calcitonin
Calcitonin
Decrease blood calcium levels by storing calcium in bones
Parathyroid Gland
4 pieces, located at the posterior surface of the thyroid gland and secretes PTH
Parathyroid Hormone (PTH or parathormone)
Helps increase serum calcium levels, and regulates the amount of phosphorus
Hypocalcemia
Can cause spasms due to overstimulation of muscles
Hypercalcemia
Can cause impaired cardiac function, can also lead to death.
Changes in the kidneys caused by PTH
Increase Ca and Mg reabsorption from kidney tubules and accelerates the elimination of P in the urine
Adrenal glands (suprarenal gland)
Small, yellow masses that lie on the top of the kidneys
Two parts of adrenal glands
Cortex and Medulla
Adrenal Cortex
Has 3 separate layers: Zona Glumerulosa, Zona Fasciculata, and Zona Reticulares
MIneralocorticoids
secreted by the outer zone (zona glomerulosa)
MIneralocorticoids
Helps with water and electrolyte homeostasis and indirectly manage blood pressure
Aldosterone
Principal mineralocorticoid, helps decrease potassium levels and increase sodium
Sodium retention
Leads to water retention increasing blood volume and therefore increasing blood pressure (WHERE SALT GOES, WATER FOLLOWS)
Glucocorticoids
Secreted by the middle zone (Zona Fasciculata)
Cortisol
Helps with glucose metabolism and provides extra reserve energy
Also acts as an anti-inflammatory
Sex hormones
Secreted by the inner zone (Zona reticularis)
Androgens for MALE
Estrogens for FEMALE
Adrenal Medulla
Same as cells of sympathetic nervous system
Epinephrine and Norepinephrine
Two hormones secreted by the adrenal medulla during times of stress
Preparation for “fight or flight” induced by epinephrine/norepinphrine
- HR and BP increase
- Vessels constrict
- Liver releases glucose reserved
Pancreas
Has BOTH endocrine and exocrine properties, located at the posterior of the stomach
Endocrine properties of pancreas
Islets of Langerhans (alpha cells and beta cells)
Two major hormone secreted by islets of Langerhans
Insulin and Glucagon
Insulin
Secreted by beta cells, in response to elevated serum glucose level
Glucagon
Secreted by alpha cells in response to decreased serum glocuse level
Major role of insulin and glucagon
Carbohydrates, Fat, and Protein metabolism
Female Sex Glands
Ovaries and Placenta
Ovaries
Located on the right and left side of the uterus, produce two hormones (estrogen and progesterone)
Estrogen
Producing female secondary sex characteristics (pubic hair, maturation of reproductive organ)
Progesterone
Prepares the reproductive organs which started by estrogen
Placenta
Temporary endocrine gland during pregnancy
Replaces estrogen and progesterone secretion during pregnancy
Male Sex Organs
Testes
Testes
Located outside the body, contained in the scrotum and secretes testosterone
Testosterone
Development of male secondary sex characteristics (pubic, facial, axillary hair, deepening of voice, maturation of reproductive organs, development of muscle and bone mass)
Also necessary for sperm production
Thymus Gland
Located posterior to the sternum and secretes thymosin, which helps with immune system
T Lymphocytes
Carry out immune reactions to antigens, thymus gland programs the information in utero and the first few months of life
Pineal Gland
Small cone shaped gland on the roof of the third ventricle
Hormone secreted of the pineal gland
Melatonin
Melatonin
Inhibits reproductive activated by inhibiting gonadotropic hormones, which prevents children from maturing until puberty
Induce sleep
Affect mood
Impact menstrual cycles