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Drugs List > Endocrine > Flashcards

Endocrine Flashcards

1
Q 
What class is Metformin
MOA
A

Biguanides

Reduces hepatic gluconeogenesis and increases glucose sensitivity

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2
Q

What drug is in class Biguanides

A

Metformin

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3
Q

Mechanism of action for biguanides (metformin)

A

Reduces hepatic gluconeogenesis and increases glucose sensitivity

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4
Q

Side Effects and class of Metformin

A

Nausea and Vomiting

Interract with diuretics and digoxin

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5
Q

What class is Glicazide

A

Sulphonylureas

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6
Q

What drug is in class Sulphonylureas

A

Glicazides

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7
Q

Mechanism of action of Sulphonylureas (Glicazide)

A

Increases insulin secretion from pancreas

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8
Q

Side Effects of Sulphonylureas

A

Hypoglycaemia

Interacts with warfarin and NSAIDs

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9
Q

What class is Pioglitazone

A

Thiazolidinediones

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10
Q

What drug is in class Thiazolidinediones

A

Pioglitazone

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11
Q

MOA of Thiazolidinediones (Pioglitazone)

A

Increases insulin sensitivity in muscle and adipose tissue

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12
Q

Side Effects of Thiazolidinediones (Pioglitazone)

A

Weight Gain

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13
Q

What class is Exenatide

A

Glucagon-like peptide-1 receptor (GLP-1) agonist

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14
Q

What drug is in class Glucagon-like peptide-1 receptor (GLP-1) agonist

A

Exenatide

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15
Q

MOA of Glucagon-like peptide-1 receptor (GLP-1) agonist (exenatide)

A

Incretin analogue – improves glucose control

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16
Q

Side Effects of Glucagon-like peptide-1 receptor (GLP-1) agonist (exenatide)

A

Asthenia (abnormal physical weakness or lack of energy.)

17
Q

What drug is in class Dipeptidyl peptidase-4 (DPP-4) Inhibitor

A

Sitagliptin

18
Q

What class is Sitagliptin

A

Dipeptidyl peptidase-4 (DPP-4) Inhibitor

19
Q

MOA of Dipeptidyl peptidase-4 (DPP-4) Inhibitor (sitagliptin)

A

Reduces inactivation of incretins

20
Q

Dipeptidyl peptidase-4 (DPP-4) Inhibitor (sitagliptin)

A

Headache

21
Q

What drug is in class Lipase Inhibitor

A

Orlistat

22
Q

What Class is Orlistat

A

Lipase Inhibitor

23
Q

MOA of Lipase Inhibitor Orlistat

A

Inhibition of GI uptake of dietary fats

24
Q

Side Effects of Lipase Inhibitor Orlistat

A

Oily Stool, Faecal Urgency

25
Q

Name a blood glucose reducing hormone

A

Insulin

26
Q

What is insulin

A

a blood glucose reducing hormone

27
Q

side effects of medical insulin

A

Hypoglygaemia

Interacts with digoxin and beta-blockers

28
Q

How does blood glucose reducing hormone, Insulin, work

A

Stimulation of glucose uptake by cells

29
Q

Name some thyroid hormones

A 
Levothyroxine Sodium (T4)
Liothyronine Sodium (T3)
30
Q 
What are Levothyroxine Sodium (T4) and
Liothyronine Sodium (T3)
A

Thyroid Hormones

31
Q 
Side Effects of Thyroid Hormones Levothyroxine Sodium (T4) and
Liothyronine Sodium (T3)
A

Diarrhoes, Vomiting

Interact with oral anti-coagulants

32
Q 
MOA of Levothyroxine Sodium (T4) and 
Liothyronine Sodium (T3)
A

Synthetic Hormones

Drugs List (1 decks)

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