Endocrine Flashcards

1
Q

How do Endocrine organs operate?

A

via synthesis an secretion of hormone chemical messengers.

-They are ductless and rely on secretory cells

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2
Q

Describe Exocrine glandular epithelium

A

maintains continuity with surface epithelium, and has polarized cells with polarized secretions

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3
Q

Describe Endocrine glandular epithelium

A

lose contact with surface epitheliu and have non-polarized cells with non-polarized secretions (into surrounding blood capillaries) thyroid is the exception

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4
Q

grave’s disease

A

hypersecretion of thyroid hormones; exophthalmos edema behind eyes causes them to protrude

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5
Q

Goiters

A

inadequate iodine intake

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6
Q

which cells secrete the Thyroid hormone?

A

follicular cells

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7
Q

which cells secrete calcitonin

A

para-follicular cells (c-cells)

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8
Q

function of calcitonin on bone

A

inhibits osteoclastic activity which reduces levels of clacium in bloodstream

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9
Q

where are oxiphil cells found?

A

in parathyroid gland of older individuals lots of mitochondria in the cell

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10
Q

effects of PTH

A
  • stmulates osteoclastic activity
  • increases absorption of calcum from gastrointestinal tract when calcium is present in diet
  • increases the reabsorption of calcium in proximal convoluted tubules

increases blood calcium level and causes bone erosion

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11
Q

where does the cortex of the adrenal gland arise form

A
  • mesoderm

- similar to gonads and secretes steroid hormones

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12
Q

where does the medulla of the adrenal gland arise from

A
  • neural crest

- secretes catecholamines

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13
Q

cells of zona fasciculata are termed what?

A

spongiocytes lipid filled cells

-arranged in long rows between fenestrated capillaries

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14
Q

what steroid hormone is produced in the Zona Fasciulata?

A

glucocorticoids– cortisol or corticosterone

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15
Q

what steroid hormone is produced in the zona glomerulosa

A

mineralcorticoids– aldosterone

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16
Q

what steroid hormone is produced in zona reticularis

A

Androgens (DHEA)

17
Q

GLUT 2

A

insulin-independent transporter of glucose; located highly in the islet cells; transports glucose to insular cells and hepatocytes

18
Q

GLUT 4

A

insulin-dependent transporter of glucose; removes glucose from blood

19
Q

Type I Diabetes mellitus

A

-juvenile onset; due to an autoimmune attack upon islets

20
Q

Type II Diabetes Mellitus

A
  • adult onset; resistance of tissues to effects of insulin; leading cause of blindness, renal failure and amputations
21
Q

Par ditalis is also refered to as what?

A

Adenohypophysis

22
Q

Par Nervosa is also referred to as what?

A

Neurohypophysis

23
Q

MSH- secreting cells

A

found in Pars intermedia

24
Q

what are the glia cells in the neurohypophysis called?

A

pituicytes

25
Q

where is vasopressin stored?

A
  • ADH
  • stimulates the kidney to produce a concentrated urine
  • lack of vasopressin causes Diabetes Insipdus
  • stored in herring bodies