Endocrine Flashcards
patho of SIADH
There is a hypersecretion of ADH from posterior pituitary gland. This goes to kidneys and promotes excessive water reabsorbtion.
This leads to dilutional hyponatremia.
Think H2O intoxication
causes of SIADH
oat cell carcinoma AKA bronchogenic tumor
viral pneumonia
neurologic disorder
analgesics, anesthetics, & stress
serum osmolality normal level
275-295
how to quickly calculate serum osmolality
2x sodium level
fluid status in low serum osmolality?
fluid volume overolad
fluid status in high serum osmolality
concentrated/dehydration
urine specific gravity normal levels
1.005-1.030
assessment of SIADH patient
decreased LOC/lethargy confusion/personality changes Headache NVD anorexia hyponatremia (cerebral edema) seizures/coma
medical management of SIADH
treat underlying cause - surgery/radiation/chemo
fluid restriction
Na replacement w/ 3%NS
Lasix if overloaded after 3%
medications for SIADH
ADH inhibitor (vaprisol) demeclocycline (abx) - abx that interferes with ADH effects in tubules phenytoin/fludrocortisone - blocks effects of ADH in tubules
nursing management for SIADH
fluid volume status
neuro
seizure precautions
oral care
patho/causes of DI
improper posterior pitutitary development
neuro trauma
pituitary tumor
kidney disease - nephrogenic DI from failure to respond to ADH
dilantin - blocks effect of ADH on tubules
what is the one thing you think of when you hear DI?
water wasting
assessment of patient with DI
polyuria polydipsia dehydration hypotension tachycardia decreased LOC seizures
what labs would you see with DI?
low urine osmolality/specific gravity/sodium
high serum osmolality/specific gravity/sodium