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DIT Step 2 > Endocrine > Flashcards

Endocrine Flashcards

1
Q

biguanide

A

metformin

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2
Q

sulfonylureas

A

glimepiride
glipizide
glyburide

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3
Q

thiazolidinediones

A

rosiglitazone

pioglitazone

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4
Q

DDP-4 inhibitors

A

sitagliptin
saxagliptin
linagliptin
alogliptin

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5
Q

GLP-1 receptor agonists

A

exenatide
liraglutide
dulaglutide
albiglutide

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6
Q

SGLT-2 inhibitors

A

dapagliflozin
canagliflozin
empagliflozin

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7
Q

alpha-glucosidase inhibitor

A

acarbose

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8
Q

amylin analog

A

pramlintide

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9
Q

meglitinides

A

nateglinide

repaglinide

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10
Q

non-insulin drugs for diabetes that cause weight gain

A

sulfonylureas

thiazolidinoediones

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11
Q

non-insulin drugs for diabetes that cause weight loss

A

GLP-1 receptor agonists
SGLT-2 inhibitors
amylin analog
meglitinides

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12
Q

non-insulin drugs for diabetes that cause hypoglycemia

A

sulfonylureas
amylin analog
meglitinides

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13
Q

non-insulin drugs for diabetes with SE UTIs and major mycotic infections

A

SGLT-2 inhibitors

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14
Q

non-insulin drugs for diabetes that may cause edema and worsen CHF

A

thiazolidinediones

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15
Q

non-insulin drugs for diabetes that you should not give to renal diseased patients

A 
metformin
sulfonylureas
DPP-4 inhibitors
GLP-1 receptor
SGLT-2 inhibitors
meglitinides
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16
Q

MOA metformin

A

decreases hepatic gluconeogenesis

improves insulin sensitivity (improves glucose uptake in tissues)

17
Q

MOA sulfonylureas

A

inhibits potassium-ATP channels, increasing insulin release

*requires functioning pancreas

18
Q

MOA thiazolidinediones

A

activate PPARgamma, improving tissue uptake of glucose and increased insuline sensitivity

19
Q

MOA DPP-4 inhibitors

A

improve glucose-responsive insulin release
modest effect on gastric emptying
DDP-4 breaks down GLP-1, so inhibit that to increase GLP-1 levels

20
Q

MOA GLP-1 receptor agonists

A

decreases glucagon secretion
improves glucose-responsive insulin release
delay gastric emptying
improve satiety

21
Q

MOA SGLT-2 inhibitors

A

block reabsorption of glucose in renal tubule

22
Q

MOA alpha-glucosidase inhibitor

A

blocks absorption of carbohydrates in the intestine

23
Q

MOA amylin analog

A

augments insulin release
suppression glucagon
improves satiety

24
Q

MOA meglitinides

A

inhibits potassium-ATP channel, increasing insulin release

1/2 strength SFUs

DIT Step 2 (8 decks)

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