Endocrine Flashcards
adrenal fatigue primary botanicals
codonopsis pilosula eleutherococcus senticosus glycyrrhiza glabra panax ginseng; p. quinquefolium rehmannia glutinosa rhodiola rosea schisandra chinensis withania somnifera
hypothyroidism primary botanicals
fucus vesiculosus
commiphora mukul
diabetes primary actions
adaptogen
endocrine tonic (insulin-mimetic)
hypoglycemic
diabetes primary botanicals
cinnamomum zeylanicum galega officinalis gymnema sylvestre momordica charantia trigonella foenum-graecum
cinnamon CI?
pregnancy - emmenagogue, abortifacient
oil CI skin, internally
Effectiveness of cinnamon for lowering hemoglobin A1C in patients with type 2 diabetes?
Cinnamon lowered HbA1C 0.83% (95% CI, 0.46-1.20) compared with usual care alone lowering HbA1C 0.37% (95% CI, 0.15-0.59).
[RCT]
Cinnamon + usual care = better than usual care
codonopsis pilosula
dang shen
qi tonic - particularly respiratory system
antispasmodic
analgesic
asthma
digestive weakness
CHD
doses >60g may cause chest pain
used as cheaper substitute to panax ginseng
Found in change of season soup
commiphora mukul
guggul
hypolipidemic
hypoglycemia
antioxidant
Guggulsterones act on bile acid receptors to help process lipids & cause hypolipidemic effect
Decreases effects of thyroid suppressive drugs
CI: IBD
Caution patients with coagulation disorders - may increase coagulation time
may decease avail of propranolol if taken concomitantly
eleutherococcus senticosus
Siberian ginseng
adaptogen
immune modulating
tonic
stress mgmt improved physical strength - athletes fatigue generalized weakness frequent infections
CI: during acute phase infections
may increase effectiveness of some antibiotics
6 wks on, 2 wks off, repeat
Elderly Subjects give E. senticosus (70%) were more likely to state that they received active therapy than subjects given placebo (20%; p
fucus vesiculosus
kelp, bladderwrack
contains iodide
thyroid stimulant
anti-rheumatic
demulcent
Flucoxanthin: Has one of the greatest antioxidant activities of all edible seaweeds may contribute to stabilizing effects in thyroiditis.
Di-IodoTyrosine may promote thyroid function by making it easier for the thyroid gland to make active thyroid hormones.
galega officinalis
goat’s rue
hypoglycemic
galactagogue
ganoderma lucidum
reishi
immunostimulant antiviral adaptogen hypotensive anti-cancer hepatoprotective
glycyrrhiza glabra
anti-inflammatory
expectorant
demulcent
adaptogen
CI: cholestatic and cirrhotic liver disease hypertension hypokalemia severe kidney insufficiency pregnancy anorexia nervosa edema CHF
Interactions: do not prescribe alongside: digoxin diuretics laxative other K+ depleting drugs
gymnema sylvestre
hypoglycemic/antidiabetic
insulin-mimetic
hypocholesterolemic
reduce appetite & taste stimuli of sweetness
caution: celiac disease
insulin resistance
melissa officinalis
TSH antagonist
anti-spasmodic
carminative
topical anti-viral
insomnia
depression
HSV
nervous stomach
b/c TSH antagonist, may interfere with innate thyroid hormone levels or thyroid supplementation
mormordica charantia
bitter melon
hypoglycemic
emmenagogue
anti-viral
late-onset DM stomach ulcers (fruit)
CI: avoid in pregnancy
rehmannia glutinosa
di huang / chinese foxglove
most yin of the adaptogens - rarely used solo; usually combined with yang adaptogen
anti-pyretic
adaptogen
anti-hemorrhagic
anti-inflammatory
CI: deficiency spleen w/dampness, deficient yang
rhodiola rosea
Fatigue, anxiety, depression, mental & physical exhaustion, to improve mental performance, [] &memory, esp. when under stress, to enhance physical performance and endurance.
Insomnia , anorexia, HA, htn when d/t the above. Fertility.
May improve sexual function in men. Adjuvant treatment of cancer. Prevent high altitude sickness. Erythropoiesis.
caution: bipolar
schisandra chinensis
hepatoprotective antioxidant adaptogen nervine tonic anti-tussive
chronic vital hepatitis
improved physical performance
endurance
resistance to effects of stress
cautions: pregnancy
trigonella foenum-graecum
fenugreek
hypoglycemic hypolipidemic demulcent nutritive immunomodulator galactagogue adaptogen anxiolytic analgesic
DM
hyperlipidemia
PMS
CI: pregnancy
Fenugreek seeds significantly decreased fasting blood glucose (P=0.007) and HbA1c (P=0.0001), serum levels of insulin (P=0.03), homeostatic model assessment for insulin resistance (P=0.004), total cholesterol (P=0.005) and triglycerides (P=0.0001) and increased serum levels of adiponectin (P=0.001) compared with placebo
withania somnifera
ashwagandha
nervine tonic adaptogen sedative (mild) anti-inflammatory immunomodulator anti-anemic
healthy aging general debility aphrodisiac nervous exhaustion long term stress hypothyroidism OA (knee)
pregnancy category A
no proven increase in frequency of malformation or other harmful effects on the fetus despite consumption by a large number of women
pregnancy category B1
no increase in frequency of malformation of other harmful effects on the fetus from limited use in women. No evidence of increased fetal damage in animal studies.
pregnancy category B2
no increase in frequency of malformation of other harmful effects on the fetus from limited use in women. animal studies are lacking.
pregnancy category B3
no increase in frequency or malformation of other harmful effects on the fetus from limited use in women.
Evidence of increased fetal damage in animal studies exists, although relevance to humans is unknown.
pregnancy category C
has caused or is associated with a substantial risk of causing harmful effects on the fetus or neonate without causing malformations
pregnancy category D
has caused or is associated with a substantial risk of causing fetal malformation or irreversible damage
pregnancy category X
high risk of damage to fetus
lactation category C
compatible with breastfeeding
lactation category CC
compatible with breastfeeding but use caution
Lactation category ND
no data available
lactation category SD
strongly discouraged in breastfeeding
lactation category X
CI in breastfeeding
