Endocrine Flashcards

1
Q

adrenal fatigue primary botanicals

A
codonopsis pilosula
eleutherococcus senticosus
glycyrrhiza glabra
panax ginseng; p. quinquefolium
rehmannia glutinosa
rhodiola rosea
schisandra chinensis
withania somnifera
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2
Q

hypothyroidism primary botanicals

A

fucus vesiculosus

commiphora mukul

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3
Q

diabetes primary actions

A

adaptogen
endocrine tonic (insulin-mimetic)
hypoglycemic

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4
Q

diabetes primary botanicals

A
cinnamomum zeylanicum
galega officinalis
gymnema sylvestre
momordica charantia
trigonella foenum-graecum
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5
Q

cinnamon CI?

A

pregnancy - emmenagogue, abortifacient

oil CI skin, internally

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6
Q

Effectiveness of cinnamon for lowering hemoglobin A1C in patients with type 2 diabetes?

A

Cinnamon lowered HbA1C 0.83% (95% CI, 0.46-1.20) compared with usual care alone lowering HbA1C 0.37% (95% CI, 0.15-0.59).

[RCT]

Cinnamon + usual care = better than usual care

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7
Q

codonopsis pilosula

A

dang shen

qi tonic - particularly respiratory system
antispasmodic
analgesic

asthma
digestive weakness
CHD

doses >60g may cause chest pain

used as cheaper substitute to panax ginseng
Found in change of season soup

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8
Q

commiphora mukul

A

guggul

hypolipidemic
hypoglycemia
antioxidant

Guggulsterones act on bile acid receptors to help process lipids & cause hypolipidemic effect

Decreases effects of thyroid suppressive drugs

CI: IBD
Caution patients with coagulation disorders - may increase coagulation time
may decease avail of propranolol if taken concomitantly

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9
Q

eleutherococcus senticosus

A

Siberian ginseng

adaptogen
immune modulating
tonic

stress mgmt
improved physical strength - athletes
fatigue
generalized weakness
frequent infections

CI: during acute phase infections
may increase effectiveness of some antibiotics

6 wks on, 2 wks off, repeat

Elderly Subjects give E. senticosus (70%) were more likely to state that they received active therapy than subjects given placebo (20%; p

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10
Q

fucus vesiculosus

A

kelp, bladderwrack

contains iodide

thyroid stimulant
anti-rheumatic
demulcent

Flucoxanthin: Has one of the greatest antioxidant activities of all edible seaweeds  may contribute to stabilizing effects in thyroiditis.
Di-IodoTyrosine may promote thyroid function by making it easier for the thyroid gland to make active thyroid hormones.

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11
Q

galega officinalis

A

goat’s rue

hypoglycemic
galactagogue

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12
Q

ganoderma lucidum

A

reishi

immunostimulant
antiviral
adaptogen
hypotensive
anti-cancer
hepatoprotective
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13
Q

glycyrrhiza glabra

A

anti-inflammatory
expectorant
demulcent
adaptogen

CI:
cholestatic and cirrhotic liver disease
hypertension
hypokalemia
severe kidney insufficiency
pregnancy
anorexia nervosa
edema
CHF
Interactions: do not prescribe alongside:
digoxin
diuretics
laxative
other K+ depleting drugs
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14
Q

gymnema sylvestre

A

hypoglycemic/antidiabetic
insulin-mimetic
hypocholesterolemic

reduce appetite & taste stimuli of sweetness

caution: celiac disease
insulin resistance

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15
Q

melissa officinalis

A

TSH antagonist
anti-spasmodic
carminative
topical anti-viral

insomnia
depression
HSV
nervous stomach

b/c TSH antagonist, may interfere with innate thyroid hormone levels or thyroid supplementation

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16
Q

mormordica charantia

A

bitter melon

hypoglycemic
emmenagogue
anti-viral

late-onset DM
stomach ulcers (fruit)

CI: avoid in pregnancy

17
Q

rehmannia glutinosa

A

di huang / chinese foxglove

most yin of the adaptogens - rarely used solo; usually combined with yang adaptogen

anti-pyretic
adaptogen
anti-hemorrhagic
anti-inflammatory

CI: deficiency spleen w/dampness, deficient yang

18
Q

rhodiola rosea

A

Fatigue, anxiety, depression, mental & physical exhaustion, to improve mental performance, [] &memory, esp. when under stress, to enhance physical performance and endurance.
Insomnia , anorexia, HA, htn when d/t the above. Fertility.
May improve sexual function in men. Adjuvant treatment of cancer. Prevent high altitude sickness. Erythropoiesis.

caution: bipolar

19
Q

schisandra chinensis

A
hepatoprotective
antioxidant
adaptogen
nervine tonic
anti-tussive

chronic vital hepatitis
improved physical performance
endurance
resistance to effects of stress

cautions: pregnancy

20
Q

trigonella foenum-graecum

A

fenugreek

hypoglycemic
hypolipidemic
demulcent
nutritive
immunomodulator
galactagogue
adaptogen
anxiolytic
analgesic

DM
hyperlipidemia
PMS

CI: pregnancy

Fenugreek seeds significantly decreased fasting blood glucose (P=0.007) and HbA1c (P=0.0001), serum levels of insulin (P=0.03), homeostatic model assessment for insulin resistance (P=0.004), total cholesterol (P=0.005) and triglycerides (P=0.0001) and increased serum levels of adiponectin (P=0.001) compared with placebo

21
Q

withania somnifera

A

ashwagandha

nervine tonic
adaptogen
sedative (mild)
anti-inflammatory
immunomodulator
anti-anemic
healthy aging
general debility
aphrodisiac
nervous exhaustion
long term stress
hypothyroidism
OA (knee)
22
Q

pregnancy category A

A

no proven increase in frequency of malformation or other harmful effects on the fetus despite consumption by a large number of women

23
Q

pregnancy category B1

A

no increase in frequency of malformation of other harmful effects on the fetus from limited use in women. No evidence of increased fetal damage in animal studies.

24
Q

pregnancy category B2

A

no increase in frequency of malformation of other harmful effects on the fetus from limited use in women. animal studies are lacking.

25
Q

pregnancy category B3

A

no increase in frequency or malformation of other harmful effects on the fetus from limited use in women.
Evidence of increased fetal damage in animal studies exists, although relevance to humans is unknown.

26
Q

pregnancy category C

A

has caused or is associated with a substantial risk of causing harmful effects on the fetus or neonate without causing malformations

27
Q

pregnancy category D

A

has caused or is associated with a substantial risk of causing fetal malformation or irreversible damage

28
Q

pregnancy category X

A

high risk of damage to fetus

29
Q

lactation category C

A

compatible with breastfeeding

30
Q

lactation category CC

A

compatible with breastfeeding but use caution

31
Q

Lactation category ND

A

no data available

32
Q

lactation category SD

A

strongly discouraged in breastfeeding

33
Q

lactation category X

A

CI in breastfeeding