Endocrine Flashcards

1
Q

What is the Chemical (or Molecular) Level?

A

It consists of atoms and molecules that form the foundation of all matter.

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2
Q

What are atoms?

A

The smallest stable chemical units that form the foundation of all matter.

Example: Carbon, hydrogen, oxygen, nitrogen atoms.

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3
Q

What are molecules?

A

Groups of atoms bonded together, working in coordination to form compounds.

Example: Water (H2O), glucose (C6H12O6), DNA (deoxyribonucleic acid).

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4
Q

What is the Cellular Level?

A

It includes cells and organelles, which are the basic structural and functional units of life.

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5
Q

What are cells?

A

The basic structural and functional units of life, composed of atoms, molecules, and organelles.

Example: Eukaryotic cells (human cells, plant cells) vs. prokaryotic cells (bacteria).

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6
Q

What are organelles?

A

Specialized structures within a cell that perform specific functions.

Example: Nucleus (houses DNA), mitochondria (energy production), ribosomes (protein synthesis).

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7
Q

What is the Tissue Level?

A

A group of similar cells working together to perform a specific function.

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8
Q

What is an example of epithelial tissue?

A

Skin cells forming a protective layer.

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9
Q

What is an example of muscle tissue?

A

Cardiac, skeletal, and smooth muscle cells contract to generate movement.

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10
Q

What is an example of nervous tissue?

A

Neurons that transmit electrical signals.

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11
Q

What is the Organ Level?

A

A group of different tissues working together to perform specific functions.

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12
Q

What is an example of an organ?

A

Heart: Composed of muscle, connective, and nervous tissues, functions to pump blood.

Example: Lungs: Comprised of epithelial, connective, and muscle tissues to facilitate breathing.

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13
Q

What is the Organism Level?

A

An individual living entity made up of multiple organ systems working in coordination.

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14
Q

What are examples of organisms?

A

Humans, animals, and plants.

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15
Q

What is homeostasis?

A

The process of maintaining a stable internal environment in the body despite external changes.

Example: Temperature regulation, fluid balance, pH balance.

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16
Q

What is intrinsic regulation?

A

Automatic response within a cell, tissue, or organ to environmental changes.

Example: Blood flow to tissues increases during exercise.

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17
Q

What is extrinsic regulation?

A

Controlled by external systems like the nervous and endocrine systems.

Example: Nervous system triggering a fight-or-flight response.

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18
Q

What are the components of a homeostatic mechanism?

A
  1. Receptor: Detects the change. 2. Control Center: Processes the information and sends instructions. 3. Effector: Carries out the instructions to restore balance.
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19
Q

What is negative feedback?

A

Works to counteract a change, restoring the system to normal.

Example: Temperature regulation—body shivers when cold to generate heat, sweats when hot to cool down.

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20
Q

What is positive feedback?

A

Amplifies the change, often leading to a specific outcome.

Example: Childbirth—contractions increase until the baby is delivered.

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21
Q

What is the function of the endocrine system?

A

Regulates long-term processes like growth, metabolism, and reproduction through hormone secretion.

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22
Q

What are endocrine glands?

A

Glands that release hormones directly into the bloodstream.

Example: Pituitary gland, thyroid, adrenal glands.

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23
Q

What are exocrine glands?

A

Glands that have ducts and release substances onto epithelial surfaces.

Example: Sweat glands, salivary glands.

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24
Q

What is the difference between the nervous and endocrine systems?

A

Nervous System: Fast, short-lived, specific effects. Endocrine System: Slower, longer-lasting, widespread effects.

25
What is the hypothalamus?
The master control center that regulates the endocrine system and coordinates the autonomic nervous system.
26
What is the pituitary gland?
Often called the 'master gland,' it releases hormones that regulate other endocrine organs. ## Footnote Example: Anterior lobe secretes growth hormone (GH), thyroid-stimulating hormone (TSH).
27
What does the thyroid gland produce?
Produces T3 (triiodothyronine) and T4 (thyroxine) that regulate metabolism.
28
What is the role of parathyroid glands?
Produce parathyroid hormone (PTH) which increases blood calcium levels.
29
What regulates thyroid function?
A negative feedback mechanism regulates thyroid hormone levels.
30
What is hypothyroidism?
A condition characterized by low thyroid hormone levels, leading to symptoms like fatigue, weight gain, and cold intolerance.
31
What is hyperthyroidism?
An overproduction of thyroid hormones, leading to symptoms like weight loss, increased heart rate, and nervousness.
32
What is the adrenal gland?
Situated above the kidneys, it has two distinct parts: adrenal cortex and adrenal medulla.
33
What does the adrenal cortex produce?
Produces 24+ corticosteroids that affect metabolism by altering gene transcription in target cells.
34
What is aldosterone?
A mineralocorticoid that controls water and electrolyte balance. ## Footnote Example: Aldosterone increases sodium reabsorption in kidneys, promoting water retention and increasing blood pressure.
35
What are glucocorticoids?
Hormones like cortisol that regulate metabolism. ## Footnote Example: Cortisol helps the body respond to stress by increasing glucose availability for energy.
36
What are gonadocorticoids?
Hormones that aid in the onset of puberty and secondary sexual characteristics.
37
What is the primary hormone released by the adrenal cortex in response to ACTH?
Cortisol ## Footnote Cortisol helps the body respond to stress by increasing glucose availability for energy.
38
What hormones are produced in the zona reticularis of the adrenal cortex?
Androgens (e.g., testosterone) ## Footnote Androgens produced here play a role in libido and the development of muscle mass.
39
What are the primary hormones produced by the adrenal medulla?
Epinephrine (adrenaline) and norepinephrine (noradrenaline).
40
What is the primary function of epinephrine and norepinephrine?
Part of the 'fight or flight' response.
41
What effect does epinephrine have on skeletal muscles?
Mobilizes glycogen reserves, increasing ATP for quick energy.
42
What is the function of melatonin?
Regulates circadian rhythms (sleep-wake cycle) and acts as an antioxidant. ## Footnote Melatonin levels rise at night, inducing sleepiness.
43
What are the main hormones produced by the pancreas?
Insulin, glucagon, somatostatin, and pancreatic polypeptide.
44
What is the function of insulin?
Reduces blood glucose by promoting glucose uptake by cells and converting it to glycogen. ## Footnote Insulin reduces blood glucose and promotes tissue storage of glucose as glycogen.
45
What is the function of glucagon?
Stimulates liver glycogen breakdown and increases blood glucose levels. ## Footnote Glucagon helps raise blood glucose by releasing glucose from liver storage.
46
What is the role of enteroendocrine cells in the gastrointestinal tract?
Secrete hormones that coordinate digestive processes.
47
What are the endocrine functions of the kidneys?
Produce calcitriol, erythropoietin, and renin.
48
What is the function of Atrial Natriuretic Peptide (ANP)?
Lowers blood pressure by reducing sodium and water retention by kidneys.
49
What is the function of thymosin?
Promotes T lymphocyte development and maturation.
50
What is the primary hormone produced by the testes?
Testosterone.
51
What are the functions of estrogens?
Regulate menstrual cycles and female secondary sex characteristics.
52
What is the function of leptin?
Regulates appetite by signaling fullness.
53
What are amino acid derivatives in hormones?
Hormones derived from amino acids, such as epinephrine and melatonin.
54
What are peptide hormones?
Hormones made of short chains of amino acids, like insulin.
55
What are steroid hormones?
Lipid-based hormones derived from cholesterol, such as testosterone and cortisol.
56
What is the mechanism of action for peptide and catecholamine hormones?
Bind to cell membrane receptors and activate second messenger systems.
57
What happens to hormone production with aging?
Hormone production often declines with age.
58
What is hyperglycemia?
A condition characterized by elevated blood glucose levels.
59
What is diabetes mellitus?
A metabolic disorder marked by chronic high blood sugar levels.