Endocrine Flashcards
Doc for type 1 DM,gestational DM
Alfrezza
Side effect: hypoglycaemia
Ultra short acting insulin
LAG
Lispra
Aspart
Glucine
Ultra long acting insulin
Glargine, detemir
Name some sulfonylureas
Tolbutamide
MOA of GLP-1 agonist
Stimulate insulin release, delay gastric emptying
Eg. Exanatide, dulaglutide
Are dpp4 safe for kidney failure pts
Yes, linagliptin
Doc for type 2DM rx and for pts with micro nd macrovascular compli
Also used in pcos reducing anti-psychotic associated weight gain
Metformin
C/I in renal failure
Drug that decreases glucose release , delays gastric emptying induces satiety, given in both dm1 nd 2
Pramlintide
Insulin Drugs that cause weight gain side effect
Sulfonylureas
Insulin
Thiazolidinediones
Insulin Drugs that cause weight loss side effect
GLP-1 agonist, SGLT-2 (-), pramlintide, metformin
For diabetes retinopathy
Anti-VEGF
Bevacizumab
Doc for hyperthyroidism nd graves disease, last 2 trimesters of pregnancy
Carbimazole,methimazole
Antithyroid drug ending with uracil
Propythiouracil
- TPO
DOC for 1st trimester nd lactation nd thyroid storm
B blockers + Propylthiouracil
Radioactive iodide used for thyroid scan
I123
Radioactive iodine used for Rx of hyperthyroidism in older pts
I131
Drugs that increase apoptosis of osteoclasts nd inhibit
Bisphosphonates
Except Zolendronate (iv once a year) all are oral
Rx of choice for osteoporosis, hypercalcemia, pagets d/s
Zolendronate
SE: osteonecrosis of jaw , inc risk of bone fracture
Only class of drug that acts both on bone formation and resorption
Strontium ranealate
Rx for pts of postmwnopausal osteoporosis
Raloxifine
Rx for anovulation, oligospermia, delayed puberty
GnRH agonist : Gosarelin, busarelin
Se: hot flushes, vaginal atropy
Doc for ER/PR + breast cancer
Tamoxifin
Toremifene is used for Rx of tamoxifin resistance
Rx of postmenopausal osteoporosis
Raloxifin
Rx of postmenopausal osteoporosis
Raloxifin
Doc for infertility
Clomifine citrate
Aromatase convert testosterone to estrogen name some
Letrozole, vorozole
Also used for postmenopausal breast cancer, PCOS
What are the drugs used for emergency contraception
Levonorgestrol<3
Ulipristol<5
IUCD >5
Drug used for abortion
Mifepristone+misoprostol
Se: bleeding
Drug abused by athletes
Nandrolone
Name some 5 alpha reductase inhibitor
Finastride
Also used for hirsutism
Doc to induce labour
Oxytoxin
Doc for uterine relaxants
Nifedipine
Drugs for gh deficiency
Somatotropin
Se: carpel tunnel,hyperglycemia
Name an inhibitor of gh
Somatostatin
Used in acute esophageal varicel bleeding, VIPoma
