Endocrine Flashcards

1
Q

Doc for type 1 DM,gestational DM

A

Alfrezza

Side effect: hypoglycaemia

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2
Q

Ultra short acting insulin

A

LAG
Lispra
Aspart
Glucine

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3
Q

Ultra long acting insulin

A

Glargine, detemir

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4
Q

Name some sulfonylureas

A

Tolbutamide

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5
Q

MOA of GLP-1 agonist

A

Stimulate insulin release, delay gastric emptying
Eg. Exanatide, dulaglutide

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6
Q

Are dpp4 safe for kidney failure pts

A

Yes, linagliptin

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7
Q

Doc for type 2DM rx and for pts with micro nd macrovascular compli
Also used in pcos reducing anti-psychotic associated weight gain

A

Metformin
C/I in renal failure

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8
Q

Drug that decreases glucose release , delays gastric emptying induces satiety, given in both dm1 nd 2

A

Pramlintide

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9
Q

Insulin Drugs that cause weight gain side effect

A

Sulfonylureas
Insulin
Thiazolidinediones

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10
Q

Insulin Drugs that cause weight loss side effect

A

GLP-1 agonist, SGLT-2 (-), pramlintide, metformin

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11
Q

For diabetes retinopathy

A

Anti-VEGF
Bevacizumab

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12
Q

Doc for hyperthyroidism nd graves disease, last 2 trimesters of pregnancy

A

Carbimazole,methimazole

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13
Q

Antithyroid drug ending with uracil

A

Propythiouracil
- TPO

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14
Q

DOC for 1st trimester nd lactation nd thyroid storm

A

B blockers + Propylthiouracil

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15
Q

Radioactive iodide used for thyroid scan

A

I123

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16
Q

Radioactive iodine used for Rx of hyperthyroidism in older pts

A

I131

17
Q

Drugs that increase apoptosis of osteoclasts nd inhibit

A

Bisphosphonates
Except Zolendronate (iv once a year) all are oral

18
Q

Rx of choice for osteoporosis, hypercalcemia, pagets d/s

A

Zolendronate
SE: osteonecrosis of jaw , inc risk of bone fracture

19
Q

Only class of drug that acts both on bone formation and resorption

A

Strontium ranealate

20
Q

Rx for pts of postmwnopausal osteoporosis

A

Raloxifine

21
Q

Rx for anovulation, oligospermia, delayed puberty

A

GnRH agonist : Gosarelin, busarelin
Se: hot flushes, vaginal atropy

22
Q

Doc for ER/PR + breast cancer

A

Tamoxifin
Toremifene is used for Rx of tamoxifin resistance

23
Q

Rx of postmenopausal osteoporosis

A

Raloxifin

24
Q

Rx of postmenopausal osteoporosis

A

Raloxifin

25
Q

Doc for infertility

A

Clomifine citrate

26
Q

Aromatase convert testosterone to estrogen name some

A

Letrozole, vorozole
Also used for postmenopausal breast cancer, PCOS

27
Q

What are the drugs used for emergency contraception

A

Levonorgestrol<3
Ulipristol<5
IUCD >5

28
Q

Drug used for abortion

A

Mifepristone+misoprostol
Se: bleeding

29
Q

Drug abused by athletes

A

Nandrolone

30
Q

Name some 5 alpha reductase inhibitor

A

Finastride
Also used for hirsutism

31
Q

Doc to induce labour

A

Oxytoxin

32
Q

Doc for uterine relaxants

A

Nifedipine

33
Q

Drugs for gh deficiency

A

Somatotropin
Se: carpel tunnel,hyperglycemia

34
Q

Name an inhibitor of gh

A

Somatostatin
Used in acute esophageal varicel bleeding, VIPoma