Endocrine Flashcards

1
Q

Lente (Vetsulin) Insulin: Dog
1. Insulin source
2. Units/mL
3. Duration of Action

A
  1. Porcine
  2. 40U/mL
  3. 8-14 hours
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2
Q

NPH Insulin: Dog
1. Insulin source
2. Units/mL
3. Duration of Action

A
  1. Recombinant Human
  2. 100U/mL
  3. 4-10 hours
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3
Q

PZI Insulin: Dog
1. Insulin source
2. Units/mL
3. Duration of Action

A
  1. Recombinant Human
  2. 40U/mL
  3. 10-16 hours
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4
Q

Glargine Insulin (Lantus): Dog
1. Insulin source
2. Units/mL
3. Duration of Action

A
  1. Recombinant human analog
  2. 100U/mL
  3. 8-16 hours
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5
Q

Glargine Insulin (Toujeo): Dog
1. Insulin source
2. Units/mL
3. Duration of Action

A
  1. Recombinant human analog
  2. 300 U/mL
  3. 12-24 hours
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6
Q

Detemir Insulin: Dog
1. Insulin source
2. Units/mL
3. Duration of Action

A
  1. Recombinant human analog
  2. 100U/mL
  3. 8-16 hours
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7
Q

What clinicopathologic features can alter serum fructosamine?

A
  1. Panhypoproteinemia
  2. Azotemia
  3. Hypoalbuminemia
  4. Hyperlipidemia
  5. Hemolysis
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8
Q

To what degree of glucose does a FreeStyle accurately interpret?

A

< 90mg/dL

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9
Q

What percentage of dogs are identified to have cataracts at the time of diabetes diagnosis?

A

14%

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10
Q

Mechanism of Action
Exenatide-ER

A

GLP-1RA inhibitor

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11
Q

Mechanism of Action
Glipizide

A

K-ATP channel inhibitor; stimulates insulin release

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12
Q

Mechanism of Action
Acarbose

A

Alpha-glucosidase inhibitor

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13
Q

Mechanism of Action
Velagliflozin

A

SGLT-2 antagonist

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14
Q

Mechanism of Action
Bexagliflozin

A

SGLT-2 antagonist

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15
Q

Mechanism of Action
Metformin

A

Open?

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16
Q

Essential enzyme for cortisol production

A

17-alpha-hydroxylase

17
Q

What mutation was identified in a poodle as a potential contributor to the development of PDH?

A

CRHR-1 (Corticotropin-releasing hormone receptor gene)

18
Q

What is the essential enzyme for pregnelone conversation with other steroid products?

A

3-B-hydroxysteroid dehydrogenase

19
Q
A