Endocrine Flashcards

1
Q

Oat cell cancer associated with which endocrine disorder?

A

SIADH

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2
Q

INCREASED Tsh and DECREASED T3 and T4 is associated with what?

A

myxedema coma, worse S/S than thyroid storm; decreased deep tendon reflexes, hypothermia, bradycardiac, slow/shallow RR

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3
Q

What medication is given for SIADH? What fluids?

A

Dilantin, 3% for severe hyponatremia

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4
Q

Etiology of DKA

A

young, Type I, new onset/noncompliance, infection, stress

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5
Q

Etiology of HHS

A

older, Type II, pancreatitis, TPN

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6
Q

Adrenal crisis medications and treatment

A

fluids and steroids; 0.9% NaCl; Decadron 1st, hydrocortisone after testing or known adrenal insufficiency

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7
Q

S/S of thyroid storm

A

decreased TSH, Increased T3/T4; fever, tachycardia, AMS, goiter, Inc LDH, inc bili

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8
Q

Treatment for thyroid storm

A

cooling, fluids/electrolyte replacement, plasma exchange, Iodine/lithium, pronanolol, Tylenol for fever; NO ASPIRIN

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9
Q

Treatment for myxedema coma

A

Rewarming, ABC’s, 3% for severe hyponatremia, Synthroid, rule out adrenal crisis

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10
Q

Is serum NA increased or decreased with SIADH?

A

decreased; dilutional hyponatremia d/t kidneys retaining water and decreased U/O: DILUTED; monitor for seizures

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11
Q

SIADH treatment

A

Identify cause, fluid restriction, 3%, Dilantin (inhibits ADH secretion), no hypotonic or free water; diuretics, do NOT correct Na too quickly

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12
Q

Urine specific gravity in SIADH

A

INCREASED because urine is concentrated; >1.030

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13
Q

Urine output in DI patients

A

6-24 L/day

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14
Q

Urine specific gravity in DI

A

LOW; 1.001-1.005

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15
Q

Serum NA and serum osm are increased or decreased in DI?

A

Increased, increased urine output= increased Na d/t water loss, Increased Na= increased osm

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16
Q

What two drugs are given for DI?

A

Vasopressin, DDAVP (ADH in drug form)

17
Q

Pathophys of DI

A

not enough ADH, ADH present but kidneys are not able to respond= abnormal water regulation in body by kidneys; keeps Na, lets water go, inc UO

18
Q

Pathophys of SIADH

A

too much ADH, too much hormone causes decrease in NA, retain H2O which leads to water toxicity