Endocrine Flashcards
Insulin
Organ: Pancreas
Cause: When blood glucose is high
Effect: Converts glucose to glycogen in body cells/liver (non target)
Body effect: Lowers blood glucose
Antagonist: Glucagon
Glucagon
Organ: Pancreas
Cause: Low blood glucose
Effect: Converts glycogen to glucose in liver
Body Effect: Increases blood glucose
Antagonist: Insulin
ADH
Organ: Posterior pituitary gland
Cause: By dehydration
Effect: Increases water reabsorption in kidneys
Body Effect: More water in blood
ACTH
Organ: Anterior pituitary
Cause: By hypothalamus/stress
Effect: Stimulates adrenal cortex
Body effect: Stimulates release of cortisol and aldosterone
PTH
Organ: Parathyroid gland
Cause: Low blood calcium
Effect: Takes calcium out of bones and puts it into blood
Body effect: Increased blood calcium
Antagonist: Calcitonin
Calcitonin
Organ: Thyroid gland
Cause: High blood calcium
Effect: Moves calcium from blood into bones
Body Effect lower blood calcium
Antagonist: PTH
Epinephrine/Norepinephrine
Organ: Adrenal medulla
Cause: Stimulated by medulla (sympathetic NS)
Effect: Goes to whole body, short term stress, converts glycogen into glucagon for extra energy
Body effect: Increased heart rate, increased blood pressure, increased blood glucose
Aldosterone
Organ: Adrenal cortex
Cause: Low salt concentration in blood
Effect: Increases water reabsorption in kidneys by putting more sodium in blood
Body effect: Higher sodium in blood, more water in blood, higher blood pressure
Cortisol
Organ: Adrenal cortex
Cause: by ACTH, long term stress
Effect: converts proteins into glucose in liver/muscle cells
Body effect: Increased blood glucose
hGH
Organ: anterior pituitary
Cause: Stimulation from hypothalamus
Effect: Stimulates growth of bones and muscle cells, decreases fat by increasing metabolism
Body effect: Higher growth of bones, higher metabolism
Thyroxine
Organ: Thyroid
Cause: activation from TSH
Effect: Increases metabolism in body cells
Body Effect: Higher metabolism
TSH
Organ: Anterior pituitary
Cause: stimulated by TRH from hypothalamus
Effect: Stimulates release of thyroxine
Body Effect: increased body metabolism
Thyroid Disorders
Goiters
Cause: Too little thyroxine produced leads to overproduction of TSH, overstimulated thyroid
Symptoms: Enlarged thyroid, low thyroxine
Treatment: Iodine
Hypothyroidism
Cause: Too little thyroxine produced, malfunctioning thyroid
Symptoms: Lethargy, weight gain
Hyperthyroidism
Cause: too much thyroxine produced, lack of negative feedback
Symptoms: High Body Temp, Increased weight loss
Treatment:
Diabetes Mellitus
Type 1
Cause: Body doesn’t produce enough insulin
Symptoms: High blood sugar, glucose in urine
Treatment: Injecting insulin
Type 2
Cause: body doesn’t respond to insulin
Symptoms: same as type 1
Treatment: diet and exercise
Diabetes Insipidus
Causes: Posterior pituitary doesn’t make enough ADH or kidney doesn’t respond to ADH
Symptoms: Excessive urine release (16L per day), low energy level