Endocrine Flashcards

1
Q

Prolactin output is under neural control, an increase in what neurotransmitter decreases prolactin release?

A

An increase in dopamine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What medication that is a DA (dopamine agonist) antagonist can cause hyperprolactinemia?

A

metoclopramide (Reglan)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Luteinizing hormone-releasing hormone stimulates the release of what two hormones in the anterior pituitary gland?

A

FSH

LH

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Name the hormones released by the post. pituitary and the hormones released by the anterior pituitary?

A

Post: oxytocin and ADH

Ant: FLAT PiG
FSH
LH
ACTH
TSH
Prolactin
Growth hormone
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What disorder results if you produce too much ADH, and if you produce too little ADH?

A

Too much: SIADH

Too little: DI

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What medication can cause SIADH and what medication can treat SIADH?

A

Carbamazepine can cause SIADH (anticonvulsant) and the treatment medication is Demeclocycline (decreases responsiveness to ADH)

carbamazepine is not the main cause of SIADH, that would be TBI, and Demeclocycline is only one of a few treatments for SIADH. Also can treat with fluid restriction and hypertonic NaCl if Na+ is lower than 120 mEq/L but do not correct > than 1 mEq/L/hr

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Somatotropin is also known as?

A

Growth hormone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Which nerve can be damaged during thyroid/parathyroid surgery?

A

RLN

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Increased thyroid hormone causes an increase cascade of what? (independent of the ANS)

A

Increased thyroid hormone leads to increased BMR leading to increased 02 consumption and increased CO2 production.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

True or False:

hyperthyroidism increases MAC and hypothyroidism decreases MAC?

A

False
Hyper- and Hypo- thyroid does NOT affect the CNS thus it has no effect on MAC.

BUT hyperthyroidism causes an increased CO thus increased anesthetic uptake in the blood and a Slower induction.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Most common cause of Hyperthyroidism?

A

Grave’s disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Most common cause of hypothyroidism?

A

Hashimoto’s thyroiditis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Low TSH + High T3 and T4 describes?

A

Hyperthyroidism

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

High TSH + Low T3 and T4 describes?

A

hypothyroidism

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Thyroid storm can occur in hyper, euthyroid, or hypo patients?

A

hyper and euthyroid patients

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

When is the complication of thyroid storm most likely to happen?

A

6-18 hours after surgery

17
Q

What is myxedema coma?

A

complication of severe hypothyroidism, the coma is a consequence (not a cause) of severely impaired thyroid function.

18
Q

What is cretinsim?

A

complication of neonatal hypothyroidism that leads to limited physical and mental development

19
Q

Amiodarone contains a significant amount of what by weight? (making it a bad choice for someone with thyroid issues)

A

Iodine

20
Q

How do Thionamides work?

A

Inhibit thyroid synthesis by blocking iodine addition to the tyrosine residues on thyroglobulin, but require 6-7 weeks to achieve euthyroid

Propylthiouracil
PTU
Methimazole
Carbimazole