endocarditis, pericarditis, Rheumatic fever Flashcards
Native Valve endocarditis
Strep. viridans, staph aureus, entercocci
IV drug users endocarditis
S. aureus, tricupsid valve most affected
Prosthetic valve endocarditis
S. aureus, gram (-), fungi
osler nodes
painful, violascous red lesions of fingers, toes, feet
janeway
painless red lesion of palms and soles
Roth spots
exudative lesions of retina
how do dx endocarditis
3 blood cultures 1 hr apart, echo, TEE (helpful to see what valves are involved), Duke Criteria
presence of vegetation is diagnositc
Duke Criteria major criteria
two + blood cultures of a typical causative microorganism, echo evidence showing a new valvular regurge
Duke Criteria minor criteria
predisposing factor, fever higher than 100.4, vascular phenomena (embolic dz, pulm infarction), immunologic phenomena, positive blood culture
tx of endocarditis
gentamicin + ceftriaxone or vanco
Rheumatic Heart Disease
immune response 2-3 wks after B hemolytic strep throat
most affected valve of RHD?
mitral, then aortic (2/3 may have chronic valvular change)
typical lesion of RHD?
perivascular granuloma w/ vasculitis
Jones Criteria Major?
carditis, erythema marginatum, subcutaneous nodules, chorea, polyarthritis
Jones Criteria Minor?
fever, polyarthralgias, reversible prolongation of PR interval, rapid ESR, C-reactive protien
RHD tx?
bed rest, salicylates (ASA), IM PCN
RHD tx for PCN alergic
erythromycin
what are some ways pelple can get endocarditis?
direct intravascular contaminations from bacteremia- dental, upper respiratory, urologic, and lower GI porcedures
what are some clinical features of endocarditis?
fever (can be absent in the elderly), nonspecific sx (cough, dyspnea, arthralgias, back or flank pain, GI complaints)
-pallor and splenomegaly, strokes and emboli may occur
what do almost 90% of endocarditis pts have ?
stable murmur, but this may be absent in right-sided infections
when is antibiotic prophylaxis recommended w/ invasive dental work or surgical procedures?
pt with prosthetic valves, previous IE, some congenital heart conditions, some acquireed valve diorsder, hypertrophic cardiomyopathy and cardiac trasnplant recipeitns w/ vavulopathy
what is the antibiotic prophylaxis drug of choice?
amoxicillin
what are some pericardial disorders?
acute pericarditis, perciardial effusion, or pericardial tamponade
what is the most common cause of acute pericarditis?
idiopathic or due to viral infxn
what are some other causes of acute pericarditis?
bacterial infxn,autoimmune or conncective tissue dz, neoplams, radiation theraphy, chemo, drug toxicity, cardiac surrgery, or myxedema
what population is percarditis most common?
men and those younger than 50