ENDO1 Flashcards
Prostaglandin E1
Alprostadil
Prostaglandin F2-alpha analog
Carboprost tromethamine
Prostaglandin E1 analog
Misoprostol
Prostaglandin E2, PGE2
Dinoprostone
Prostacyclin, PGI2
Epoprostenol
Clinical application of thromboxane (TXA2)
None
Chemotactic factor in inflammation
LTB4
Lipooxygenase inhibitor
Zileuton
BLACK BOX WARNING
Montelukast (Singulair) = serious neuropsychiatric events that may include suicidal thoughts or actions (not given in less than 12 months)
Ranitidine (Zantac) = contain unacceptable levels of N-nitrosodimethylamine (NDMA)
Etarnercept (Enbrel) = risk for tuberculosis
Sertraline (Zoloft) = increased the risk of suicidal thoughts and behavior in pediatric and young adult patients
Bedaquiline (for treatment of drug-resistant tuberculosis) = possible cardiac toxicity and sudden death
Fluoroquinolones = risk of tendinitis and tendon rupture (Achilles tendon)