Endo Drugs

Question 1

Preferred treatment for GH deficiency (acromegaly)

Answer 1

SS analogue octeotride; lanreotide

Question 2

Other treatment for GH deficiency (acromegaly)

Answer 2

DA agonist: cabergoline; bromocriptine

Question 3

Treating nephorgenic DI

Answer 3

Demeclocycline

Question 4

Thyroid hormone replacement therapy

Answer 4

Levothyroxine sodium

Liothyronine sodium

Question 5

Treatment of hyperthyroidism

Answer 5

Thionamides (anti-thyroid drugs) e.g. Carbimazole; Propylthiouracil

Question 6

Treatment of Cushing’s

Answer 6

Metryapone (inhibits 11 beta hydroxylase)

Ketoconazole - enzymes inhibitor

Question 7

Treatment of Conn’s

Answer 7

MR antagonists:
Spironolactone
Epleronone

Question 8

Treatment of Addison’s

Answer 8

Oral hydrocortisone and fludrocortisone

Question 9

Treatment of ACTH deficiency

Answer 9

Hydrocortisone

Question 10

Treatment of Addisonian crisis

Answer 10

0.9% NaCl - rehydrate

High dose Hydrocortisone

Question 11

Treatment of Congenital Adrenal Hyperplasia

Answer 11

Dexamethasone
Hydrocortisone
Fludrocortisone

Question 12

Treatment of PCOS

Answer 12

Metformin

Clomiphene - anti-oestergroen - stops negative feedback so GnRH and LH/FSH increase

Question 13

DA antagonists - anti-emetics and anti-psychotics

causes of hyperproactinaemia

Answer 13

Anti-emetics = metadopromide
Anti-psychotics = phenothiacizines

Question 14

Treatment of Hyperprolactinaemia

Answer 14

DA agonists - bromocriptine cabergoline