Endo Flashcards
The pulp lacks ___ circulation, which severely limits its ability to cope with __, __ and ___.
Collateral
Bacteria
Necrotic tissue
Inflammation
The pulp possesses unique, hard tissue-secreting cells called ___ as well as ___ cells that can differentiate into ___ that form more dentin in an attempt to protect the pulp from injury.
Odontoblasts
Mesenchymal
Osteoblasts
The sensibility of the dental pulp is controlled by __ and ___ afferent nerve fibers.
A-delta
C
A-delta fibers are [large/small] myelinated nerves that enter the root canal and divide into smaller branches, coursing __ through the pulp. What kind of pain do they perceive?
Large
Coronally
Immediately perceived as quick, sharp, momentary pain, which dissipates quickly upon removal of the stimulus
The intimate association of A-delta fibers with the odontoblastic cell layer and dentin is referred to as the ___ complex
Pulpodentinal
In pulpitis (pulpal inflammation) the response is ___ and disproportionate to the challenging stimulus (aka: ___) This response is induced by the effects of ____ that are released in teh inflammed pulp.
Exaggerated
Disproportionate
hyperalgesia
Inflammatory mediators
Progression of pulpal inflammation can change the quality of pain response. As the exaggerated A-delta fiber pain subsides, pain ___ and is perceived as a ___. This second pain symptom is from __ fibers.
Seemingly remains
Dull, throbbing pain
C nerve
Describe C fibers
Small, unmyelinated nerves that course centrally in the pulp stroma
In contrast to A-delta fibers, they are not directly involved with the pulpodentinal complex and are not easily provoked.
When does C fiber pain surface?
With tissue injury and is mediated by inflammatory mediations, vascular changes in blood volume, and blood flow, and increases in tissue pressure.
When C fiber pain dominates, it signifies irreversible local tissue damage
True or false, with increasing inflammation of pulp tissues, C fiber pain becomes the only pain feature.
True
True or false… hot liquids or foods can increase intrapulpal pressure to levels that excite C fibers
True
The pain is diffuse and can be referred to a distant site or to other teeth
What happens with sustained inflammation?
It is detrimental to pulpal recovery, finally terminating in tissue necrosis.
Describe the signs/symptoms of a normal tooth.
Asymptomatic
Produces mild/moderate transient response to thermal or electrical stimuli that subsides almost immediately after removal of stimulus
No painful response to percussion or palpation
In reversible pulpitis, thermal stimuli causes what kind of a response?
Quick, sharp, hypersensitive response that subsides as soon as the stimulus is removed
What kind of irritant can affect the pulp and may cause reversible pulpitis?
Early caries or recurrent decay
Periodontal SRP
Deep restorations without a base
True or false… reversible pulpitis is a disease not a symptom
False, the opposite. It is a symptom, not a disease
If the irritant is removed, the pulp reverts back to an uninflammed state
If the irritant remains the symptoms may lead to irreversible pulpitis
What are the two ways reversible pulpitis (RP) can be clinically distinguished from a symptomatic irreversible pulpitis (IR)?
1) RP causes momentary painful response to thermal change that subsides as soon as stimulus is removed. IR causes painful response to thermal change that lingers after removal of stimulus.
2) RP does not involve complaint of spontaneous (unprovoked) pain.
What is the most frequent crossover point from RP to IP?
Frank penetration of bacteria into the pulp
True or false, symptomatic irreversible pulpitis may resolve if caries is removed.
False. By definition the pulp has been damaged beyond repair
What are microscopic findings of symptomatic irreversible pulpitis (SIP)?
1) Microabscesses of the pulp begin as tiny zones of necrosis within dense acute inflammatory cells
2) histologiclaly intact myelinated and unmyelinated nerves may be observed in areas with dense inflammation and cellular degeneration
What occurs following irreversible pulpitis?
Pulp death may occur quickly or may require years; it may be painful, or more frequently, asymptomatic. The end result is necrosis.
SIP is characterized by ___ pain
Spontaneous, unprovoked, intermittent or continuous
How do temperature changes affect a tooth with SIP?
Elicit prolonged episodes of pain that linger after the thermal stimulus is removed.
True or false. Radiographs are generally sufficient for diagnosing IP
False.
True or false.. occasionally, patients may report that a postural change, such as lying down or bending over, induces pain in a tooth with SIP
True
how are radiographs helpful in diagnosing SIP?
Can be helpful in identifying suspect teeth only.
Thickening of the apical portion of the PDL may become evident on radiographs in the advanced stage.
True or false.. electrical pulp testing is an excellent way to diagnose SIP
False, it has little value
How does asymptomatic irreversible pulpitis (AIP) compare to SIP microscopically?
Very similar.
There are no clinical symptoms but inflammation produced by caries, caries excavation, or trauma occurs.
Pulp necrosis is death of the pulp that results from what three things?
Untreated irreversible pulpitis
Traumatic injury
Any event that causes long-term interruption of the blood supply to the pulp.
True or false… pulpal necrosis is all or none. How is this so?
False. It may be partial or total.
Partial necrosis may manifest with some of the symptoms associated with irreversible pulpitis. For example, a tooth with two canals could have an inflamed pulp in one canal and a necrotic pulp in other.
Total necrosis is asymptomatic before it affects the PDL, and there is no response to thermal or electrical pulp tests.
True or false… anterior teeth may show some discoloration in the crown due to necrosis
True
What occurs in the periapical space due to necrosis?
Protein breakdown products and bacteria and their toxins eventually spread beyond the apical foramen; this leads to thickening of the PDL and manifests as tenderness to percussion and chewing.
Describe the microscopic findings of necrotic pulp
As inflammation progresses, tissue continues to disintegrate in the center to form an increasing region of liquefaction necrosis
Because of the lack of collateral circulation and the unyielding walls of dentin, there is insufficient draining of inflammatory fluids
The result is localized increases in tissue pressure, causing the destruction to progress unchecked until the entire pulp is necrotic
Bacteria are able to penetrate and invade into the dentinal tubules (it is necessary to remove the superficial layers of dentin during cleaning and shaping)
What is hyperplastic pulpitis?
Reddish, cauliflower-like growth of pulp tissue through and around a carious exposure. The proliferative nature of this type of pulp is attributed to low-grade, chronic irritation of the pulp and the generous vascular supply characteristically found in young people.
What is internal resorption?
Most commonly identified during radiographic examination. If undetected, internal resorption eventually perforates the root.
Chronic pulpitis - (chronic inflammatory cells, multinucleated giant cells adjacent to granulation tissue. Necrotic pulp coronal to resorptive defect)
Only prompt endo therapy can stop the process and prevent further tooth destruction
Partial pulp vitality is necessary for active internal resorption
True or false.. a completely nonvital tooth can undergo internal root resorption.
False. Partial pulp vitality is necessary for active internal resorption.
Apical lesions of pulpal origin are ___ responses to irritants from the root canal system
Inflammatory
In regards to apical diseases, Patient symptoms may range from an asymptomatic response to various symptoms including…
Slight sensitivity to chewing
Sensation of tooth elongation
Intense pain
Swelling
Fever
Malaise
What is the most indicative sign of apical inflammatory lesions?
Radiographic bone resorption, but this is unpredictable. Apical lesions are frequently not visible on radiographs.
True or false.. there is no correlation between histologic findings and clinical signs, symptoms, and duration of the apical lesion.
True
The terms acute and chronic apply only to clinical symptoms
symptomatic apical periodontitis refers to painful inflammation around the apex and can result from…
Extension of pulpal disease into the apical tissue
Canal overinstrumentation or overfill
Occlusal trauma such as bruxism
True or false… symptomatic apical periodontitis may occur around vital and nonvital teeth, conducting pulp tests is the only way to confirm the need for endodontic treatment
True
Even with the presence of symptomatic apical periodontitis, the apical PDL may radiographically appear ___
Within normal limits or only slightly widened.
Is symptomatic apical periodontitis painful during percussion tests?
It may be
If a tooth is vital, yet has symptomatic apical periodontitis, ___ can often relieve the pain. If the pulp is necrotic and remains untreated, ___ symptoms may appear as the disease advances to the next stage, ___
Simple occlusal adjustment
Additional
Acute apical abscess
What often causes throbbing apical pain in symptomatic apical periodontitis?
Because of the little room for expansion of the PDL, increased pressure can also cause physical pressure on the nerve endings, which subsequently cause intense, throbbing apical pain
In histopahtologic examination of symptomatic apical periodontitis reveals a localized inflammatory infiltrate within the ___
PDL
Asymptomatic apical periodontitis is a ___, ___ lesion.
Long-standing, asymptomatic or mildly symptomatic lesion
True or false, asymptomatic apical periodontitis is usually accompanied by radiographically visible apical bone resorption.
True
In AAP, bacteria and their endotoxins cascading out into the apical region from a necrotic pulp cause extensive ___ of __ and __ bone.
Demineralization
Cancellous and cortical
True or false… there is always extreme tenderness to percussion or palpation in AAP
False. There may be slight tenderness
How is asymptomatic apical periodontitis diagnosis confirmed?
General absence of symptoms
Radiographic presence of an apical radiolucency
Confirmation of pulpal necrosis
A totally necrotic pulp provides a safe harbor for the primarily ___ microorganisms. If there is no vascularity, there are no ___ cells
Anaerobic
Defense
AAP traditionally has been classified histologically as ___ or ___. The only accurate way to distinguish them is by ___ examination.
Apical granuloma or apical cyst
Histopathologic
What is an acute abscess?
Painful with purulent exudate around the apex
It is a result of exacerbation of symptomatic apical periodontitis from a necrotic pulp
How does an apical abscess look radiographically?
Appears WNL or only slightly thickened.
Reveals a relatively normal or slightly thickened lamina dura (because the infection has rapidly spread beyond the confines of the cortical plate before demineralization can be detected radiographically)
What is the only sign of an acute abscess?
Swelling
Acute abscess lesions can also result from infection and rapid tissue destruction arising from within ___
Asymptomatic apical periodontitis
What are the histopathologic findings of an acute abscess?
Central area of liquefaction necrosis containing disintegrating neutrophils and other cellular debris
Surrounded by viable macrophages and occasional lymphocytes and plasma cells
Bacteria are not always found in the apical tissues or within the abscess cavity
What are the presenting signs and symptoms of an acute apical abscess?
Rapid onset of swelling
Moderate to severe pain
Pain with percussion and palpation
Slight increase in tooth mobility
Extent and distribution of swelling are determined by the location of the apex and the muscle attachments and the thickness of the cortical plate
Usually the swelling remains localized. However it may become diffuse and spread widely (cellulitis)
How can an acute apical abscess be differentiated from a lateral periodontal abscess?
Pulp vitality testing and sometimes with periodontal probing.