Endo Flashcards
1
Q
example of gh receptor antagonist (treatment of acromegaly)
A
pegvisomant
2
Q
example of gh receptor antagonist (treatment of acromegaly)
A
pegvisomant
3
Q
major source of igf-I
A
liver
4
Q
peak igf I production age
A
16
5
Q
peaks of hormone secretion: gh? acth?
A
gh - night (coincides with sleep onset), acth - 6am
6
Q
percentage of cells. somatotropes? corticotropes? gonadotropes? thyrotropes?
A
somatotoropes -50%.
corticotropes - 20%.
gonadotropes -10%.
thyrotropes - 5%.
7
Q
glycoprotein hormones with common alpha subunit?
A
tsh, fsh,lh, hcg (beta subunit confer specificity)
8
Q
gnrh pulses are every?
A
60-120min
