End of Chapter Questions: CSF Flashcards
1
Q
The functions of CSF include all of the following except: A. Removing metabolic wastes B. Producing an ultrafiltrate of plasma C. Supplying nutrients to the CNS D. Protecting the brain and spinal cord
A
B. producing and ultrafiltrate of Plasma
2
Q
The CSF flows through the: A. Choroid plexus B. Pia mater C. Arachnoid space D. Dura mater
A
C. Arachnoid Space
3
Q
Substances present in the CSF are controlled by: A. Arachnoid granulations B. Blood–brain barrier C. Presence of one-way valves D. Blood–CSF barrier
A
B. Blood-brain barrier
4
Q
What department is the CSF in the third tube routinely sent to? A. Hematology B. Chemistry C. Microbiology D. Serology
A
A. Hematology
5
Q
The CSF tube that should be kept at room temperature is: A. Tube 1 B. Tube 2 C. Tube 3 D. Tube 4
A
B. Tube 2 (Microbiology)
6
Q
The presence of xanthochromia can be caused by all of the following except: A. Immature liver function B. RBC degradation C. A recent hemorrhage D. Elevated CSF protein
A
C. A recent hemorrhage
7
Q
A web-like pellicle in a refrigerated CSF specimen indicates: A. Tubercular meningitis B. Multiple sclerosis C. Primary CNS malignancy D. Viral meningitis
A
A. Tubercular meningitis
8
Q
Given the following information, calculate the CSF WBC count:
Cells counted: 80
Dilution: 1:10
Large Neubauer Squares Counted: 10
A
C. 800
9
Q
A CSF WBC count is diluted with: A. Distilled water B. Normal saline C. Acetic acid D. Hypotonic saline
A
C. Acetic Acid
10
Q
A total CSF cell count on a clear fluid should be: A. Reported as normal B. Not reported C. Diluted with normal saline D. Counted undiluted
A
D. Counted undiluted
11
Q
The purpose of adding Albumin to CSF before cytocentrifuging is to: A. Increase the cell yield B. Decrease the cellular distortion C. Improve the cellular staining D. Both A and B
A
D. A and B
A. Increase cell yield, B. Decrease cellular distortion
12
Q
The primary concern when pleocytosis of neutrophils and lymphocytes is found in CSF is: A. Meningitis B. CNS malignancy C. Multiple sclerosis D. Hemorrhage
A
A. Meningitis
13
Q
Neutrophils with pyknotic nuclei may be mistaken for: A. Lymphocytes B. Nucleated RBCs C. Malignant cells D. Spindle-shaped cells
A
B. Nucleated RBCs
14
Q
The presence of which of the following cells is increased in a parasitic infection? A. Neutrophils B. Macrophages C. Eosinophils D. Lymphocytes
A
C. Eosinophils
15
Q
Macrophages appear in the CSF after: A. Hemorrhage B. Repeated spinal taps C. Diagnostic procedures D. All of the above
A
D. All of the above
A. Hemorrhage, B. Repeated spinal taps, C. Diagnostic procedures
16
Q
Nucleated RBCs are seen in the CSF as a result of: A. Elevated blood RBCs B. Treatment of anemia C. Severe hemorrhage D. Bone marrow contamination
A
D. Bone marrow contamination
17
Q
After a CNS diagnostic procedure, which of the following might be seen in the CSF? A. Choroidal cells B. Ependymal cells C. Spindle-shaped cells D. All of the above
A
D. All of the above
A. Choroidal cells, B. Ependymal cells, C. Spindle-shaped cells
18
Q
Hemosiderin granules and hematoidin crystals are seen in: A. Lymphocytes B. Macrophages C. Ependymal cells D. Neutrophils
A
B. Macrophages
19
Q
Myeloblasts are seen in the CSF: A. In bacterial infections B. In conjunction with CNS malignancy C. After cerebral hemorrhage D. As a complication of acute leukemia
A
D. As a complication of acute leukemia
20
Q
Cells resembling large and small lymphocytes with cleaved nuclei represent: A. Lymphoma cells B. Choroid cells C. Melanoma cells D. Medulloblastoma cells
A
A. Lymphoma cells
21
Q
The reference range for CSF protein is: A. 6 to 8 g/dL B. 15 to 45 g/dL C. 6 to 8 mg/dL D. 15 to 45 mg/dL
A
B. 15-45 g/dL
22
Q
CSF can be differentiated from serum by the presence of: A. Albumin B. Globulin C. Prealbumin D. Tau transferrin
A
D. Tau transferrin
23
Q
In serum, the second most prevalent protein is IgG, in CSF, the second most prevalent protein is: A. Transferrin B. Prealbumin C. IgA D. Ceruloplasmin
A
B. Prealbumin
24
Q
Elevated CSF protein values can be caused by all of the following except: A. Meningitis B. Multiple sclerosis C. Fluid leakage D. CNS malignancy
A
C. Fluid leakage
25
Q
The integrity of the blood-brain barrier is measured using the: A. CSF/serum albumin index B. CSF/serum globulin ratio C. CSF albumin index D. CSF IgG index
A
A. CSF/serum Albumin index
26
Q
Given the following results, calculate the IgG index: CSF IgG: 50mg/dL Serum IgG: 2g/dL CSF Albumin: 70mg/dL Serum Albumin: 5g/dL
A
C. 1.8
27
Q
The finding of oligoclonal bands in the CSF and not in the serum is seen with: A. Multiple myeloma B. CNS malignancy C. Multiple sclerosis D. Viral infections
A
C. Multiple Sclerosis
28
Q
A CSF Glucose of 15mg/dL, WBC count of 5000, with 90% neutrophils, and protein of 80mg/dL suggests: A. Fungal meningitis B. Viral meningitis C. Tubercular meningitis D. Bacterial meningitis
A
D. Bacterial meningitis
29
Q
A patient with a blood glucose of 120mg/dL would have a normal CSF glucose of A. 20 mg/dL B. 60 mg/dL C. 80 mg/dL D. 120 mg/dL
A
C. 80 mg/dL
30
Q
CSF Lactate will be more consistently decreased in: A. Bacterial meningitis B. Viral meningitis C. Fungal meningitis D. Tubercular meningitis
A
A. Bacterial meningitis
31
Q
Measurement of which of the following can be replaced by CSF glutamine analysis in children with Reye syndrome? A. Ammonia B. Lactate C. Glucose D.α-Ketoglutarate
A
A. Ammonia
32
Q
Before performing a Gram Stain on CSF, the specimen must be: A. Filtered B. Warmed to 37°C C. Centrifuged D. Mixed
A
C. Centrifuged
33
Q
The test of choice to detect neurosyphilis is the; A. RPR B. VDRL C. FAB D. FTA-ABS
A
D. FTA-ABS
