End of Chapter Questions: CSF Flashcards
The functions of CSF include all of the following except: A. Removing metabolic wastes B. Producing an ultrafiltrate of plasma C. Supplying nutrients to the CNS D. Protecting the brain and spinal cord
B. producing and ultrafiltrate of Plasma
The CSF flows through the: A. Choroid plexus B. Pia mater C. Arachnoid space D. Dura mater
C. Arachnoid Space
Substances present in the CSF are controlled by: A. Arachnoid granulations B. Blood–brain barrier C. Presence of one-way valves D. Blood–CSF barrier
B. Blood-brain barrier
What department is the CSF in the third tube routinely sent to? A. Hematology B. Chemistry C. Microbiology D. Serology
A. Hematology
The CSF tube that should be kept at room temperature is: A. Tube 1 B. Tube 2 C. Tube 3 D. Tube 4
B. Tube 2 (Microbiology)
The presence of xanthochromia can be caused by all of the following except: A. Immature liver function B. RBC degradation C. A recent hemorrhage D. Elevated CSF protein
C. A recent hemorrhage
A web-like pellicle in a refrigerated CSF specimen indicates: A. Tubercular meningitis B. Multiple sclerosis C. Primary CNS malignancy D. Viral meningitis
A. Tubercular meningitis
Given the following information, calculate the CSF WBC count:
Cells counted: 80
Dilution: 1:10
Large Neubauer Squares Counted: 10
C. 800
A CSF WBC count is diluted with: A. Distilled water B. Normal saline C. Acetic acid D. Hypotonic saline
C. Acetic Acid
A total CSF cell count on a clear fluid should be: A. Reported as normal B. Not reported C. Diluted with normal saline D. Counted undiluted
D. Counted undiluted
The purpose of adding Albumin to CSF before cytocentrifuging is to: A. Increase the cell yield B. Decrease the cellular distortion C. Improve the cellular staining D. Both A and B
D. A and B
A. Increase cell yield, B. Decrease cellular distortion
The primary concern when pleocytosis of neutrophils and lymphocytes is found in CSF is: A. Meningitis B. CNS malignancy C. Multiple sclerosis D. Hemorrhage
A. Meningitis
Neutrophils with pyknotic nuclei may be mistaken for: A. Lymphocytes B. Nucleated RBCs C. Malignant cells D. Spindle-shaped cells
B. Nucleated RBCs
The presence of which of the following cells is increased in a parasitic infection? A. Neutrophils B. Macrophages C. Eosinophils D. Lymphocytes
C. Eosinophils
Macrophages appear in the CSF after: A. Hemorrhage B. Repeated spinal taps C. Diagnostic procedures D. All of the above
D. All of the above
A. Hemorrhage, B. Repeated spinal taps, C. Diagnostic procedures
Nucleated RBCs are seen in the CSF as a result of: A. Elevated blood RBCs B. Treatment of anemia C. Severe hemorrhage D. Bone marrow contamination
D. Bone marrow contamination
After a CNS diagnostic procedure, which of the following might be seen in the CSF? A. Choroidal cells B. Ependymal cells C. Spindle-shaped cells D. All of the above
D. All of the above
A. Choroidal cells, B. Ependymal cells, C. Spindle-shaped cells
Hemosiderin granules and hematoidin crystals are seen in: A. Lymphocytes B. Macrophages C. Ependymal cells D. Neutrophils
B. Macrophages
Myeloblasts are seen in the CSF: A. In bacterial infections B. In conjunction with CNS malignancy C. After cerebral hemorrhage D. As a complication of acute leukemia
D. As a complication of acute leukemia
Cells resembling large and small lymphocytes with cleaved nuclei represent: A. Lymphoma cells B. Choroid cells C. Melanoma cells D. Medulloblastoma cells
A. Lymphoma cells
The reference range for CSF protein is: A. 6 to 8 g/dL B. 15 to 45 g/dL C. 6 to 8 mg/dL D. 15 to 45 mg/dL
B. 15-45 g/dL
CSF can be differentiated from serum by the presence of: A. Albumin B. Globulin C. Prealbumin D. Tau transferrin
D. Tau transferrin
In serum, the second most prevalent protein is IgG, in CSF, the second most prevalent protein is: A. Transferrin B. Prealbumin C. IgA D. Ceruloplasmin
B. Prealbumin
Elevated CSF protein values can be caused by all of the following except: A. Meningitis B. Multiple sclerosis C. Fluid leakage D. CNS malignancy
C. Fluid leakage
The integrity of the blood-brain barrier is measured using the: A. CSF/serum albumin index B. CSF/serum globulin ratio C. CSF albumin index D. CSF IgG index
A. CSF/serum Albumin index
Given the following results, calculate the IgG index: CSF IgG: 50mg/dL Serum IgG: 2g/dL CSF Albumin: 70mg/dL Serum Albumin: 5g/dL
C. 1.8
The finding of oligoclonal bands in the CSF and not in the serum is seen with: A. Multiple myeloma B. CNS malignancy C. Multiple sclerosis D. Viral infections
C. Multiple Sclerosis
A CSF Glucose of 15mg/dL, WBC count of 5000, with 90% neutrophils, and protein of 80mg/dL suggests: A. Fungal meningitis B. Viral meningitis C. Tubercular meningitis D. Bacterial meningitis
D. Bacterial meningitis
A patient with a blood glucose of 120mg/dL would have a normal CSF glucose of A. 20 mg/dL B. 60 mg/dL C. 80 mg/dL D. 120 mg/dL
C. 80 mg/dL
CSF Lactate will be more consistently decreased in: A. Bacterial meningitis B. Viral meningitis C. Fungal meningitis D. Tubercular meningitis
A. Bacterial meningitis
Measurement of which of the following can be replaced by CSF glutamine analysis in children with Reye syndrome? A. Ammonia B. Lactate C. Glucose D.α-Ketoglutarate
A. Ammonia
Before performing a Gram Stain on CSF, the specimen must be: A. Filtered B. Warmed to 37°C C. Centrifuged D. Mixed
C. Centrifuged
The test of choice to detect neurosyphilis is the; A. RPR B. VDRL C. FAB D. FTA-ABS
D. FTA-ABS