Encephalitis Flashcards
Inflammation of the brain with involvement of the brain parenchyma
Encephalitis
Encephalitis common causes
herpes simplex virus
West Nile encephalitis Presentation
Nonspecific complaints: fever, malaise, body aches
Confusion, seizures, focal neuro deficits
Signs of meningoencephalitis
Confusion, seizures, focal deficits
photophobia, meningeal signs, headache
Herpes simplex virus encephalitis
Most cases due to re-inactivation of HSV-1
HSV encephalitis history
bizarre behavior
HSV encephalitis PE
speech disorder
gustatory or olfactory hallucinations
acute hearing impairment
HSV encephalitis diagnosis
Spinal tap for CSF studies
HSV PCR
HSV culture
MRI - characteristic pattern in temporal lobes, usually bilaterally
HSV encephalitis treatement
Empiric IV acyclovir
HSV encephalitis MRI findings
Coronal FLAIR MRI shows increased T2 signal
West Nile encephalitis
Suspected with fever, AMS in late spring, summer, early fall
West nile PE
AMS
extrapyramidal symptoms
Flaccid paralysis - suggestive of transverse myelitis
West nile encephalitis diagnosis
CSF resemble viral meningitis
ELISA for IgM to West Nile virus