Empirical Antibiotic Treatments

Question 1

CURB 65

Answer 1

confusion
urea > 7
resp. rate > 30
blood pressure <90 / < 61
65 yo +

Question 2

CURB 65 for mild/moderate community acquired pneumonia

Answer 2

0-2

Question 3

CURB 65 for severe community acquired pneumonia

Answer 3

3 -5

Question 4

treatment of mild/moderate community acquired pneumonia

Answer 4

oral amoxicillin

Question 5

treatment of mild/moderate community acquired pneumonia if penicillin injury

Answer 5

oral doxycycline

Question 6

treatment of severe CAP

Answer 6

oral co-amoxiclav + doxycycline

Question 7

treatment of severe CAP if penicillin allergic

Answer 7

IV levofloxacin

risk of c. diffe - one of 4C’s ciprofloxacin

Question 8

treatment of CAP if in ICU/HDU

Answer 8

Iv co-amoxiclav + clarithromycin

if pen allergic IV levofloxacin

Question 9

treatment of severe HAP

Answer 9

IV amoxicillin, metronidazole, gentamycin

step down to oral co-trimazole + metronidazole

Question 10

treatment of sever HAP if pen allergic

Answer 10

IV co-trimoaxazole + metronidazole

step down to oral co-trimazole + metronidazole

Question 11

treatment of non-severe HAP

Answer 11

oral amoxicillin + metronidazole

Question 12

treatment of non-severe HAP if penicillin allergic

Answer 12

oral co-trimoxazole + metronidazole

Question 13

treatment of acute exacerbation of COPD

Answer 13

1st line amoxicillin

2nd line doxycycline

Question 14

treatment of epiglottis

Answer 14

ceftriazone

Question 15

amoxicillin + gentamicin given together have what affect?

Answer 15

synergystic

Question 16

investigations of acute native valve endocarditis

Answer 16

2 blood cultures within the hour

Question 17

investigations of subacute native valve endocarditid

Answer 17

3 blood cultures each 6 hours apart

Question 18

treatment of acute native valve endocarditis

Answer 18

IV flucloxacillin

Question 19

treatment of subacute native valve endocarditis

Answer 19

IV amoxicillin + gentamicin

Question 20

treatment of prosthetic valve endocarditis

Answer 20

IV vancomycin + rifampicin + gentamicin

Question 21

treatment of native valve severe sepsis

Answer 21

IV vancomycin + metoropenem

Question 22

treatment of mild/moderate c. diffe

Answer 22

oral metronidazole

Question 23

treatment of severe c. diffe

Answer 23

oral vancomycin

Question 24

treatment of peritonitis / biliary tract / intra-abdominal infection

Answer 24

IV amoxicillin + metronidazole + gentamicin

step down to oral metronidazole + co-trimoxazole

Question 25

treatment of peritonitis / biliary tract / intra-abdominal infection if pen allergic

Answer 25

IV vancomycin + metronidazole + gentamicin

step down to oral metronisiazole + co-trimoxazole

Question 26

treatment of cellulitis

Answer 26

flucloxacillin

doxycycline if pen allergic

Question 27

treatment of acute septic arthritis or osteomyelitis

Answer 27

IV flucloxacillin

Question 28

treatment of acute (mild) diabetic foot infection

Answer 28

flucloxacillin or doxyxycline

Question 29

treatment of chronic (moderate) diabetic foot infection

Answer 29

flucloxacillin + metronidazole
or
doxycycline + metronidazole

Question 30

treatment of open fracture prophylaxis

Answer 30

hours IV co-amoxiclav

or IV co-trimoxazole + metronidazole

Question 31

which of the following is NOT a 4C antibiotic:

Levofloxacin, Co-amoxiclav, Clarithromycin, Clindimycin, Ceftazidime

Answer 31

CLARITHROMYCIN

Question 32

what 2 antibiotics have an anti-toxin affect?

Answer 32

linezolid, clindimycin

Question 33

duration of treatment for infective endocarditis

Answer 33

6 weeks

Question 34

what is the mortality of septic shock?

Answer 34

> 40%

Question 35

what is used for the screening of sepsis

Answer 35

NICE, SIRS, qSOFA, NEWS

Question 36

most likely pathogen causing sepsis in diverticular abscess

Answer 36

coliforms + anaerobes

Question 37

what is the source of control in patient with diverticular abscess sepsis?

Answer 37

surgical drainage of abscess

Question 38

treatment of MRSA blood infection

Answer 38

IV vancomycin