Emergency Medicine1 Flashcards
Q001. ACEIs; Toxicity
A001. Cough; rash; proteinuria; angioedema; taste changes; teratogenic effects
Q002. Amantadine; Toxicity
A002. Ataxia; livedo reticularis
Q003. Aminoglycosides; Toxicity
A003. Ototoxicity; nephrotoxicity - ATN
Q004. Amiodarone; Toxicity
A004. Pulmonary fibrosis; peripheral deposition => bluish discoloration,; arrhythmias,; hypo-/hyperthyroidism,; corneal deposition
Q005. Amphotericin; Toxicity
A005. Fever/chills; nephrotoxicity; bone marrow suppression; anemia
Q006. Antipsychotics; Toxicity
A006. Sedation; acute dystonic reaction; akathisia; parkinsonism; tardive dyskinesia; neuroleptic malignant syndrome
Q007. Azoles (e.g., fluconazole); Toxicity
A007. Inhibition of P-450 enzymes
Q008. AZT; Toxicity
A008. Thrombocytopenia; megaloblastic anemia
Q009. β-blockers; Toxicity
A009. Asthma exacerbation; masking of hypoglycemia; impotence
Q010. Benzodiazepines; Toxicity
A010. Sedation; dependence; respiratory depression
Q011. Bile acid resins; Toxicity
A011. GI upset; malabsorption of vitamins; and medications
Q012. Calcium channel blockers; Toxicity
A012. Peripheral edema; constipation; cardiac depression
Q013. Carbamazepine; Toxicity
A013. Induction of P-450 enzymes; agranulocytosis; aplastic anemia
Q014. Chloramphenicol; Toxicity
A014. Gray baby syndrome; aplastic anemia
Q015. Cisplatin; Toxicity
A015. Nephrotoxicity; acoustic nerve damage
Q016. Clonidine; Toxicity
A016. Dry mouth; severe rebound headache; hypertension
Q017. Clozapine
A017. Agranulocytosis
Q018. Corticosteroids; Toxicity
A018. Mania (acute) immunosuppression; bone mineral loss; thinning of skin; easy bruising; myopathy (chronic); cataracts
Q019. Cyclophosphamide; Toxicity
A019. Myelosuppression; hemorrhagic cystitis
Q020. Digoxin -; Toxicity
A020. GI disturbance; yellow-green visual changes; arrhythmias - junctional tachycardia or SVT,; varying amounts of AV node blocks
Q021. Doxorubicin -; Toxicity
A021. Cardiotoxicity; (dilated cardiomyopathy)
Q022. Ethyl alcohol -; Toxicity
A022. Renal dysfunction
Q023. Fluoroquinolones; Toxicity
A023. Cartilage damage in children Achilles tendon rupture
Q024. Furosemide; Toxicity
A024. Ototoxicity; hypokalemia; nephritis
Q025. Gemfibrozil; Toxicity
A025. Myositis; reversible Æ in LFTs
Q026. Halothane; Toxicity
A026. Hepatotoxicity; malignant hyperthermia
Q027. HCTZ; Toxicity
A027. Hypokalemia; hyperuricemia; hyperglycemia
Q028. HMG-CoA reductase inhibitors; Toxicity
A028. Myositis; reversible Æ in LFTs
Q029. Hydralazine; Toxicity
A029. Drug-induced SLE
Q030. Hydroxychloroquine; Toxicity
A030. Retinopathy
Q031. INH -; Toxicity
A031. Peripheral neuropathy - prevent with vitamin B6; hepatotoxicity; inhibition of P-450 enzymes; seizures with overdose
Q032. MAOIs -; Toxicity
A032. Hypertensive tyramine reaction; serotonin syndrome - with meperidine
Q033. Methanol; Toxicity
A033. Blindness
Q034. Methotrexate; Toxicity
A034. Hepatic fibrosis; pneumonitis; anemia
Q035. Methyldopa; Toxicity
A035. Pos. CoombsÀ test; drug-induced SLE
Q036. Metronidazole; Toxicity
A036. Disulfiram reaction; vestibular dysfunction; metallic taste
Q037. Niacin; Toxicity
A037. Cutaneous flushing
Q038. Nitroglycerin; Toxicity
A038. Hypotension; tachycardia; headache; tolerance
Q039. Penicillin/β-lactams ; Toxicity
A039. Hypersensitivity reactions
Q040. Penicillamine; Toxicity
A040. Drug-induced SLE
Q041. Phenytoin; Toxicity
A041. Nystagmus; diplopia; ataxia; gingival hyperplasia; hirsutism
Q042. Prazosin -; Toxicity
A042. First-dose hypotension
Q043. Procainamide; Toxicity
A043. Drug-induced SLE
Q044. Propylthiouracil; Toxicity
A044. Agranulocytosis
Q045. Quinidine; Toxicity
A045. Cinchonism -; (headache, tinnitus); thrombocytopenia; arrhythmias - torsades de pointes
Q046. Reserpine; Toxicity
A046. Depression
Q047. Rifampin; Toxicity
A047. Induction of P-450 enzymes; orange-red body secretions
Q048. Salicylates; Toxicity
A048. Fever; hyperventilation with; respiratory alkalosis; and metabolic acidosis; dehydration; diaphoresis; hemorrhagic gastritis
Q049. SSRIs; Toxicity
A049. Anxiety; sexual dysfunction
Q050. Succinylcholine; Toxicity
A050. Malignant hyperthermia
Q051. Tetracyclines; Toxicity
A051. Tooth discoloration; photosensitivity; FanconiÀs syndrome
Q052. TCAs; Toxicity
A052. Sedation; coma; anticholinergic effects; seizures; wide QRS; in severe cases - prolonged QT => torsade
Q053. Valproic acid; Toxicity
A053. Teratogenicity => neural tube defects
Q054. Vancomycin; Toxicity
A054. Nephrotoxicity; ototoxicity; Àred man syndromeÀ - histamine release, not an allergy
Q055. Vinblastine; Toxicity
A055. Severe myelosuppression
Q056. Vincristine; Toxicity
A056. Peripheral neuropathy
Q057. Acetaminophen; What is the Antidote
A057. N-acetylcysteine
Q058. Acid/alkali ingestion; What is the Antidote
A058. Upper endoscopy to evaluate for stricture
Q059. Anticholinesterases,; organophosphates; What is the Antidote
A059. Atropine; pralidoxime
Q060. Antimuscarinic/; anticholinergic agents; What is the Antidote
A060. Physostigmine
Q061. Arsenic, mercury, gold; What is the Antidote
A061. Succimer; dimercaprol
Q062. β-blockers; What is the Antidote
A062. Glucagon
Q063. Barbiturates (phenobarbital); What is the Antidote
A063. Urine alkalinization (bicarb); dialysis; activated charcoal
Q064. Benzodiazepines; What is the Antidote
A064. Flumazenil
Q065. Black widow bite -; What is the Antidote
A065. Calcium gluconate
Q066. Carbon monoxide -; What is the Antidote
A066. 100% O2; hyperbaric O2
Q067. Copper, arsenic, lead, gold -; What is the Antidote
A067. Penicillamine
Q068. Cyanide -; What is the Antidote
A068. Nitrite; sodium thiosulfate
Q069. Digitalis -; What is the Antidote
A069. Stop digitalis,; normalize K+,; lidocaine (for torsades), anti-digitalis Fab
Q070. Heparin -; What is the Antidote
A070. Protamine sulfate
Q071. Iron salts -; What is the Antidote
A071. Deferoxamine
Q072. Lead -; What is the Antidote
A072. Succimer; CaEDTA; dimercaprol
Q073. Methanol, ethylene glycol (antifreeze); What is the Antidote
A073. EtOH; fomepizole; dialysis
Q074. Methemoglobin; What is the Antidote
A074. Methylene blue
Q075. Opioids; What is the Antidote
A075. Naloxone
Q076. Phencyclidine hydrochloride (PCP); What is the Antidote
A076. NG suction
Q077. Salicylates -; What is the Antidote
A077. Urine alkalinization; dialysis; activated charcoal
Q078. TCAs; What is the Antidote
A078. Na bicarb - QRS prolongation; diazepam or lorazepam for Seizures; cardiac monitor for; arrhythmias
Q079. Theophylline; What is the Antidote
A079. Activated charcoal