Emergency Medicine - Toxicology Flashcards

0
Q

Drugs that cause bradycardia

A

BB, CCB, digoxin, lithium

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1
Q

Drugs that cause HTN

A

Sympathomimetics: Cocaine, amphetamines, designer drugs

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2
Q

Causes of conjugate eye deviation - towards or away from lesion?

A

Stroke - towards. Seizure - away.

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3
Q

Causes of hemiparesis

A

Post-ictal, stroke, ICH

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4
Q

Drug therapy for the agitated patient

A

If drug induced, drug withdrawal, or unknown - give benzo (lorazepam, midazolam). If Dementia or psychiatric cause - give antipsychotic (haloperidol).

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5
Q

Effect of anticholinergic toxicity on HR

A

Increased HR

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6
Q

Effect of synpathomimetic toxicity on HR

A

Increased HR

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7
Q

Effect of sedative toxicity on HR

A

Bradycardia

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8
Q

Effect of cholinergic toxicity on HR

A

Variable

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9
Q

Oral findings for anti cholinergic, sympathomimetic, sedative and cholinergic overdoses

A

No oral findings except for with cholinergics you get salivation

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10
Q

Effect of anticholinergic toxicity on BP

A

Variable BP

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11
Q

Effect of sympathomimetic toxicity on BP

A

High BP

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12
Q

Effect of sedative toxicity on BP

A

Low bp

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13
Q

Effect of cholinergic toxicity on BP

A

Variable bp

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14
Q

How do pupils look with anti cholinergic toxicity

A

Dilated

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15
Q

How do pupils look with sympathomimetic toxicity

A

Dilated pupils

16
Q

How do pupils look with sedative toxicity

A

Dilated or constricted

17
Q

How do pupils look with cholinergic toxicity

A

Constricted pupils

18
Q

Suspect overdose of what agent in patient with dry flushed skin?

A

Anticholinergic

19
Q

Suspect overdose of what agent in diaphoretic patient with piloerection?

A

Sympathomimetic agent

20
Q

Suspect overdose of what agent in patient with hypothermic skin?

21
Q

Suspect overdose of what agent in patient with diaphoretic skin and constricted pupils?

A

Cholinergics

22
Q

Location of tension HA, migraines, cluster HA

A

Bilateral, unilateral, unilateral in orbital/supraorbital/temporal region

23
Q

Pinpoint pupils, resp depression, lethargy, bradycardia, hypothermia, borderline hypotension

A

Opioid overdose

24
Way to remember anticholinergic toxicity
Blind as a bat, mad as a hatter, red at a beet, hot as a hare, full as a tick, dry as a bone, bowel loses tone and heart runs alone
25
Way to remember cholinergic toxicity
Dumb bells : diarrhea/diaphoresis, urination, miosis (constricted pupil), bradycardia, bronchorrhea, emesis, lacrimation, salivation/seizures Also AMS, fasciculation, weakness
26
Examples of anticholinergic drugs
Diphenhydramine (OTC cold/sleep meds), antiparkinson meds benztropine, toxic jimsonweed
27
Sympathomimetic drugs
Cocaine, amphetamines, anorectics, otc stimulants, herbal stimulants
28
Cholinergic drugs
Organophosphates, carbamates (pesticides), donepezil (ACEi for Alzheimer's), physostigmine (MG, Alzheimer's, delayed gastric emptying), nerve gas agents
29
Sedatives
Anticonvulsants, barbs, benzos, GHB, methaqualone, etoh