Emergency medications Flashcards
What class of drug is Aspirin?
NSAID
Aspirin mechanism of action
NSAID, that decreases inflammation and decreases platelet aggregation
Indications for Aspirin
ACS/Chest pain
Contraindications for Aspirin
Hypersensitivity/allergies, no ability to chew
Adverse reactions of aspirin
GI symptoms
Aspirin Dosage
324 mg, oral (3-4 pills 81 mg tablets)
What class of drug is epinephrine?
Sympathetic agonist
Mechanism of action for epinephrine
Directly affects the alpha 1, beta 1, beta 2 receptors. Vasoconstriction, increased HR/BP, increased contractility, bronchodilation
Indications for epinephrine (both 1;1,000 and 1;10,000)
1:1000 (Asthma, COPD, anaphylaxis)
1: 10,000 cardiac arrest (IV/IO only)
Contraindications for epinphrine
hypersensitivity/allergy, tachycardia, or hypertensive
Adverse reactions of epinephrine
Nausea/Vomitting, palpitations, headaches, nervousness
Dosages for Epinephrine (1000, 10,000)
1:1000-0.3 mg IM (AAC) or 5 mg nebulizer (stridor)
1:10,000-1 mg IV/IO every 3-5 minutes (cardiac arrest)
Pediatric dosage for Epinephrine
0.01 mg/kg
Epinephrine special considerations
Use caution with elderly patients or with history of heart disease. Make sure you monitor them with the cardiac monitor
Class for norepinephrine
Sympathetic agonist
Mechanism of action for NorEPI
Acts on both the alpha and beta receptors as an agonist. Vasoconstrictor, increased blood pressure
Indications for NorEPI
Shock (to maintain blood pressure/tissue perfusion), severe hypotension, and post resuscitation.
Contraindications for NorEPI
Hypersensitivity/allergy, tachycardia
Adverse reactions for norepi
palpations, anxiety, tachycardia, and tremors
Dosage for NorEPI
8-12 mcg/min IV. Maintenance infusion of 2-20 mcg/min to obtain adequate perfusion, usual dose 2-4 mcg/min. Maximum 30 mcg/min
Special considerations for norepi
one of the strongest vasopresssors available. monitor blood pressure closely
Class of drug for Amiodarone
Anti-Dysrhythmic drug
Mechanism of action for Amiodarone
Prolongs the action potential and refractory period, slows electrical conduction rate. Sodium, calcium, potassium channel blocker.
Indications for Amiodarone
V-tach, V-fib, wide complex rapid tachycardia
Contraindications for Amiodarone
Hypersensitivity/allergies, bradycardia
Adverse reactions to Amiodarone
Dizziness. Drowsiness
Dose for Amiodarone
V-fib/v-tach 300 mg may repeat at 150 mg
Stable wide complex tachycardia 150 mg
Amiodarone is which drug…
Amiodarone is a cardiac drug. Brings the heartrate down by slowing electrical conduction.
Atropine is what class of drug?
Anti-cholinergic agent
Atropine mechanism of action
Potent parasympatholytic drug that inhibits actions of acetylcholine. Indirectly increases HR and AV conduction, decreases GI secretions and dilates pupils.
Indications for Atropine
Organophosphate poisoning. Symptomatic bradycardia
Adverse reactions of Atropine
Tachycardia, flush, hot skin
Dosage for Atropine
Bradycardia: 0.5-1 mg IV/IO every 3-5 minutes as needed
Organosphosphate poisoning: 2 mg, then 4 mg, then 8 mg; can be given every 5 minutes. Titrate to effect
What class of drug is Adenosine?
Antidysrhythmic Drug
Mechanism of action for Adenosine
Derived from the breakdown of ATP, Adenosine slows AV conduction, decreases HR, acts as a “Chemical cardioversion”
Indications for Adenosine
SVT and rapid tachycardias
Contraindications for Adenosine
Bradycardia, hypersensitivity/allergies
Adverse reactions of Adenosine
Palpitations, near-syncope, dizziness, lightheadedness, chest pain, flushing, anxiety
Dosage for Adenosine
Adult: 6 mg RAPID IV/IO push; can be followed up by 12 mg
Pediatric dose for Adenosine
0.1 mg/kg
Metoprolol class of drug
Beta Blocker
Mechanism of action for Metoprolol
Beta adrenergic blocking agent; selective to the beta 1 receptor, blocking it’s effects causing; decrease in HR, myocardial contractility, cardiac output and conduction velocity
Indications for Metoprolol
Rapid A-fib, rapid atrial flutter, can be used as a second line agent after Adenosine for SVT
Contraindications for Metoprolol
Bradycardia, hypotension, hypersensitivity/allergies
Adverse reactions of Metoprolol
Bradycardia, hypotension, palpitations, dizziness, lightheadedness, and syncope
Dosage for Metoprolol
5 mg IV/IO can be given every 5 minutes. Up to 15 mg (3x) to desired effect
Albuterol class of drug
Beta 2 Agonist
Mechanism of action for Albuterol
Acts on beta 2 receptor as an agonist causing prompt bronchodilation of the lungs
Indications for Albuterol
Asthma, anaphylaxis, COPD, hyperkalemia
Contraindications for Albuterol
Hypersensitivity/allergies, CHF
Adverse reactions of Albuterol
Palpitations, tachycardia, headache
Dosage for Albuterol
2.5 mg unit dose. May repeat. Nebulizer treatment
Special considerations with Albuterol
caution in heart disease and CHF patients; perform cardiac monitoring before and after administering
Ipratropium class of drug
Anti-cholinergic
Mechanism of action for Ipratropium
Parasympatholytic which inhibits acetylcholine receptor sites. Dries respiratory secretions
Indications for Ipratropium
Asthma, COPD, anaphylaxis
Adverse reactions to Ipratropium
Dry mouth
Dosages for Ipratropium
0.5 unit dose with nebulizer
Special considerations with Ipratropium
Auscultate lung sounds before and after administration
Ondansetron (Zofran) drug class
Anti-emetic
Mechanism of action for Ondansetron
Blocks serotonin receptors; anti-emetic drug
Indications for Zofran
Nausea/vomiting
Contraindications for Zofran
Hypersensitivity/allergies
Adverse reactions to Zofran
Headache, dizziness, drowsiness
Dosage for Zofran
4-8 mg IV/IO/PO/IM
Special considerations for Zofran
Caution in pregnant patients, ask if they have already taken drug
Naloxone class of drug
Opioid Antagonist
Mechanism of action for Naloxone
Reverse the effects of the opiate and the opiate receptor
Indications for Narcan
Opiate overdose with respiratory depression
Contraindications for Narcan
none in EMS
Adverse reactions for Narcan
Confusion, agitation, Tachycardia
Dose for narcan
Adults; 2-4 mg IN/IM
0.4-2mg IV/IO
Pediatric dose:0.1 mg/kg (MAX dose of 2 mg)
Special considerations with Narcan
Make sure you hyperoxygenate the patient prior to administration of Narcan. Can help with agitation/combativeness
Ibuprofen class of drug
NSAID
mechanism of action with Ibuprofen
NSAID medication that acts peripherally as an analgesic. Has anti-inflammatory, analgesic, and anti-pyric effects
Indications for Ibuprofen
Mild to moderate pain
Contraindications of Ibuprofen
Hypersensitivity/allergies, active GI bleed, and asthma
Adverse reactions to Ibuprofen
GI irritation, renal impairment, heartburn, dizziness, drowsiness
Dosage for Ibuprofen
Adults; 200-800 mg
pediatric:5-10 mg/kg
Class of drug for Acetaminophen
Pain reliever/ Anti-pyretic
Mechanism of action for Tylenol
COX-2 inhibitor, anti-pyretic, non-opiate analgesic
Indications for tylenol
Mild to moderate pain/fever
Contraindications to tylenol
hypersensitivity/allergies, liver failure
Adverse reactions to Tylenol
Nausea, abdominal pain
Dosage for Acetaminophen
325-1000 mg PO q 4-6 hr prn] Max: 1 g/4h and 4 g/day from all sources
Fentanyl class of drug
Opiate Agonist
Mechanism of action for Fentanyl
Synthetic opiate that produces
analgesia and euphoria. CNS
Depressant.
Indications for Fentanyl
Pain control, ACS, RSI
Contraindications for Fentanyl
Bradycardia, hypotension, hypersensitivity/allergy
Adverse reactions for Fentanyl
Bradycardia, hypotension, near-syncope, respiratory depression, dizziness, drowsiness
Dosage for Fentanyl
1 mcg/kg; 50-100 mcg/dose IV/IO/IM/IN
Special considerations for Fentanyl
Cardiac monitoring and ETCO2 monitoring. Remember that this drug is listed as micrograms not milligrams.
Hydromorphone (Dilaudid) class of drug
Opioid agonist (analgesic drug)
Mechanism of action for Hydromorphone (dilaudid)
CNS depressant, produces analgesia and sedative properties
Indications for hydromorphone
Severe pain
Contraindications for Hydromorphone (dilaudid)
Hypersensitivity/allergy, bradycardia, resp depression, hypotension
Adverse reactions to hydromorphone (dilaudid)
Bradycardia, respiratory depression, hypotension
Dosage for hydromorphone (dilaudid)
0.2-0.6 mg IV/IO
Special considerations for Hydromorphone (dilaudid)
Have narcan available, cardiac monitoring and ETCO2 monitoring