Emergency Med Flashcards
Definitions: Sepsis, Systemic Inflammatory Response Syndrome, Septic Shock
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Sepsis:
- life-threatening organ dysfunction secondary to dysregulated host response to infection
- condition
- life-threatening organ dysfunction secondary to dysregulated host response to infection
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Systemic Inflammatory Response Syndrome (SIRS):
- an exaggerated defense response of the body to a stressor (infx, trauma, surgery, acute inflammation, ischemia, etc). meant to localize and then eliminate the source of the insult
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Septic Shock:
- a subset of sepsis in which particularly profound circulatory, cellular, and metabolic abnormalities are associated with a greater risk of mortality than with sepsis alone.
SIRS Criteria
Systemic Inflammatory Response Syndrome is defined as presence of 3+ of the following”
- fever > 38C (100.4F) or hypothermia <36F (96.8F)
- Tachypnea (RR > 24)
- Tachycardia (HR > 90/min)
- Leukocytosis (>12K), Leukopenia (<4K), or >10% bands
Sepsis vs Severe Sepsis
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Sepsis:
- at least 3 SIRS criteria AND a confirmed or suspected infection
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Severe Sepsis:
- sepsis WITH evidence of end-organ damage due to the tissues not getting adequate perfusion
- hypotension
- serum lactate levels (≥ 4.0mmol/L)
- pre-renal azotemia and transaminitis (elevated ALT/AST)
- sepsis WITH evidence of end-organ damage due to the tissues not getting adequate perfusion
Hour-1 Sepsis Bundle
Exam findings of Septic Shock
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Compensated:
- tachycardia
- dynamic (heaving) precordium
- bounding peripheral pulses
- reduced cap refill
- skin = warm or hot to touch (WARM shock)
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Decompensated Septic Shock:
- peripheral pulses become weak/thready
- hypotension worsens
- skin becomes cold/pale/clammy (COLD shock)
Management of Septic Shock
- fluid resuscitation with Crystalloid (NS or albumin) and colloid (blood products) up to 80ml/kg
- 1st line vasoactive agents for fluid refractory shock:
- Norepi in Warm shock (compensated)
- Epi in Cold Shock (decompensated)
- add vasopressin if refractory to vasopressors
- Restore MAP to ≥ 65 mmHG
- Restore Central venous pressure (CVP) to 8-12mmHg
How to Calculate MAP
Mean Arterial Pressure
- MAP = [(Diastolic BP x 2) + Systolic BP] / 3
ABA Burn Center Referral Criteria
Burn Treatment
- Keep the patient warm, prevent hypothermia
- < 15% BSA burns
- moist sterile dressing
- >15% BSA burns
- cover with dry sterile dressing
- decreases risk of hypothermia
- cover with dry sterile dressing
- for bigger areas → use a clean dry sheet
Parkland Formula for fluid resuscitation in a burn patient
- IV fluid of choice = Ringer’s Lactate
- 1st 24 hours:
- 4mL x kg x % BSA burned
- 1st 8 hours: give ½ of total fluid
- next 16 hours: give rest of fluid (½ of total fluid)
- Inhalation Burn: 6ml x kg x % BSA
- Electrical Burn: 7ml x kg x % BSA
Airway & Breathing Tx for Burn Patients
- >15% BSA burns: give 100% oxygen even if pulse ox is normal
- Be prepared to support ventilation
- may require an advanced airway for inhalation burns
Rule of 9s
Superficial vs Partial Thickness vs Full Thickness
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Superficial:
- epidermis only
- pain & erythema
- heals in a few days
- topical aloe vera
- injured epidermal cells peel away
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Superficial Partial Thickness:
- entire epidermal & superficial (papillary) dermis
- erythematous & skin may blister
- may be moist, weepy, or shiny
- painful & hypersensitive to touch
- blanches with pressure
- does not extend into capillary bed so it can heal better b/c basement membrane is intact
- usually heals on its own in 2-3 weeks
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Deep Partial Thickness:
- extends into deep (reticular) dermis
- Blood filled blisters
- usually Mottled pink to white in color
- Does NOT blanch
- healing time = 3+ weeks
- may require excision and skin grafting
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Full thickness:
- total loss of dermis & epidermis
- Skin appears dry, leathery, peeling
- may be white, yellow, tan/brown, or charred
- hair follicles removed easily
- often not painful
- may require escharotomy or fasciotomy
- heals by contracture & epithelial ingrowth or skin grafting
Categories of Shock Table
Stages of Shock
T or F : a normal BP rules out shock
FALSE, a normal BP does NOT rule out shock
What are 3 identifiable and treatable immediately life-threatening causes of shock?
- Bleeding
- Tension Pneumothorax
- Pericardial Tamponade
What would you use tranexamic acid for?
it is an antifibrinolytic
helps to stabilize the clotting system during hemorrhagic shock
what is the MCC of cardiogenic shock?
Acute MI
Tx of Cardiogenic Shock
Types of Distributive Shock
Neurogenic Shock Overview
Anaphylactic Shock