Emergency Drugs List Flashcards
What is the mechanism of action of adrenaline ?
Acts on both alpha and beta receptors and increases both heart rate and contractility ( beta 1 effects ) and causes peripheral vasodilation ( beta 2 effects ) or vasoconstriction ( alpha effect ).
What is the dose and route of adrenaline for cardiac resuscitation ?
IV adrenaline 1 mg every 3-5 minutes
What is the dose and route of adrenaline in an acute anaphylactic shock ?
500 micrograms repeat after 5 minutes if not response
What dose and route of hydrocortisone is given in a thyrotoxic crisis ?
IV 100 mg every 6 hours
What dose and route of hydrocortisone is given in an adrenal crisis ?
Initially IM or IV 100mg
Then 200mg every 24 hours IV infusion
OR
IM or IV 50mg every 6 hours
What dose and route of hydrocortisone is given in a severe or life-threatening asthma attack ?
IV 100mg every 6 hours until conversion to oral prednisolone is possible
What dose and route of chlorphenamine is given in an anaphylactic reaction ?
IM or IV 10 mg repeated if necessary up to 4 doses per day
What dose and route of atropine is given in bradycardia following an MI ?
IV 500 micrograms every 3 - 5 minutes
What dose and route of aspirin is given in secondary prevention of CVD ?
PO 75mg daily
What dose and route of aspirin is given in management of an MI ?
PO 300 mg
What dose and route of aspirin is given in a suspected TIA ?
PO 300mg once daily
What dose and route of aspirin is given in an ischaemic stroke ?
PO 300 mg once daily for 14 days
What dose and route of aspirin is given in mild to moderate pain ?
PO 300 - 900 mg every 4 - 6 hours
Rectal 450 - 900 mg every 4 hours
What dose and route of clopidogrel is given in a TIA ( with aspirin hypersensitivity )?
PO 75mg once daily
What is the loading dose of clopidogrel ?
300 mg
What dose and route of clopidogrel is given in prevention of atherothrombotic events after loading dose ?
PO 75mg daily
What dose and route of calcium gluconate is given in acute severe hyperkalaemia?
Slow IV injection 30mL repeat every 5 - 10 minutes it no improvement in ECG
What dose and route of diazepam is given in status epilepticus ?
IV 10 mg then 10mg after 10 minutes if required
What dose and route of lorazepam is given in status epilepticus ?
Slow IV 4mg then repeat after 5-10 minutes
What dose and route of nebulised salbutamol is given in severe or life threatening asthma ?
5 mg repeat every 20-30 minutes
What dose and route of prednisolone is given in an acute asthma attack ?
PO 40-50 mg for at least 5 days
What dose and route of morphine is given in acute pain ?
Initially PO/subcut/IM 10mg every 4 hours and adjusted to response
What dose and route of morphine is given in chronic pain ?
PO/ subcut / IM 5 - 10 mg every 4 hours
What dose and route of naloxone is given in an opioid overdose in a non medical setting ?
IM 400 microgram every 2-3 minutes continue until not required