Emergency contraception Flashcards

1
Q

Name (2) types of emergency contraception available in the UK

A
  • ‘morning after pill’
  • IUD
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2
Q

Name (2) types of emergency hormonal contraception currently available in the UK

A

Emergency hormonal contraception = ‘morning after pill’

  • Levonorgestrel → synthetic progesterone (trade name: Levonelle One Step)
  • Uripristal acetate → progesterone receptor modulator (Ella One)
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3
Q

MoA of Levonorgestrel

(as emergency contraception)

A

Levonorgestrel = synthetic progesterone (Levonelle One Step)

MoA:

  • delays ovulation for 5-7 days → after this time sperm will become non-viable
  • licensed for use within 72 hours of unprotected sex
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4
Q

How may hours after unprotected sex can Levonorgestrel (Ella One Step) be used?

A

Licensed for use within 72 hours of unprotected sex

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5
Q

MoA of Ulipristal acetate (EllaOne)

A

Ulipristal acetate = progesterone receptor modulator

MoA:

  • Delays ovulation for 5-7 days → sperm becomes non-viable
  • Licensed for use within 120 hours of unprotected sex
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6
Q

How many hours after unprotected sex can Ulipristal acetate be used for?

A

within 120 hours of unprotected sex

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7
Q

Does emergency hormonal contraception have an effect on implantation?

A
  • Both emergency pills (Levonorgestrel and Ulipristal acetate) have no known effect on disruption/inhibition of implantation
  • Their effect is due to inhibition of ovulation
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8
Q

How long after unprotected sex can IUD be used as emergency contraception?

A
  • if inserted within 5 days of unprotected sex
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9
Q

MoA of IUD as emergency contraception

A
  • copper is toxic to sperm
  • induces a sterile inflammatory response within the uterus → implantation is impossible

* must be inserted within 5 days of unprotected sex

* remains in situ for 5-10 years (depends on type)

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10
Q

Which method should be offered to all women presenting for emergency contraception?

A

IUD

  • it’s over 99% effective
  • it reminds in situ for 5-10 years (depending on type) → so long- lasting contraception
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11
Q

Contraindicaitons for levonorgestrel as an emergency contraception

A

There are no absolute contraindications, but the efficacy may be reduced by:

  • diseases of malabsorption e.g. Crohn’s
  • enzyme- inducing drugs e.g. rifampicin,
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12
Q

What to do if a patient on enzyme-inducing drug refuses IUD and wants to use Levonorgestrel?

A

Efficiacy of Levonorgestrel will be reduced → use double dose (3 mg at once may be taken)

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13
Q

Contraindications for use of Ulipristal Acetate

A
  • Diseases of malabsorption e.g. Crohn’s
  • Hypersensitivity to Ulipristal Acetate
  • Severe hepatic dysfunction
  • Enzyme inducing drugs e.g. rifampicin
    • Give 3mg levonorgestrel if the patient refuses an IUD, ulipristal acetate is absolutely contraindicated here
  • Breastfeeding – avoid breastfeeding for 7 days after taking UPA
  • Asthma insufficiently controlled by corticosteroids
  • Drugs increasing gastric pH e.g. omeprazole, ranitidine
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14
Q

Contraindications for IUD as a form of contraception

A
  • Uterine fibroids with distortion of the uterine cavity
  • Documented or suspected pelvic inflammatory disease (PID)
  • Documented or suspected STI (especially chlamydia or gonorrhoea)
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15
Q

Advice patient to seek help after receiving hormonal emergency contraception if…

A

Vomiting occurs within:

  • 2 hours of taking Levonorgestrel
  • 3 hours of taking Ulipristal acetate

*this is because medication may not have been absorbed

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16
Q

Adverse effects of hormonal emergency contraception

A
  • nausea
  • dizziness
  • menstrual disturbance
  • abdo pain
17
Q

When to perform a pregnancy test after receiving hormonal emergency contraception?

A
  • no sooner than 3 weeks of unprotected sex
18
Q

What risk patient’s using IUD as emergency contraception should be advised of?

A
  • increased relative risk of ectopic pregnancy following insertion of an IUD
  • to be alert if her next period is >5 days late with reduced bleeding, especially coupled with severe lower abdominal pain
19
Q

What to do if a pregnancy test is positive after use of IUD as an emergency contraception method?

A

Urgent USS scan to locate the pregnancy

*as increased risk of ectopic pregnancy with IUD use

20
Q

Adverse effects of IUD use

A
  • pelvic infection
  • expulsion of IUD
  • bleeding
  • pelvic pain