Emergencies Flashcards
What is anaphylaxis?
Anaphylaxis is a severe, life-threatening generalised or systemic hypersensitivity reaction
What is the most common cause of anaphylaxis in children?
What is the pathophysiology behind this?
What age group does it most commonly occur in?
In what age group is it most fatal?
Food allergies cause 85% of anaphylaxis reactions
Pathophysiology - Type 1 IgE mediated reactions. Release of histamine and other agents causes capillary leak, wheeze, cyanosis, oedema and urticaria.
Most anaphylaxis reactions occur in children <5 however the more fatal anaphylaxis occurs in adolescents with an allergy to nuts
What are some of the signs and symptoms that may present in a patient with an acute anaphylaxis reaction?
A - Airway - swelling, hoarseness, stridor
B - Tachypnoea, wheeze, cyanoisis, sats <92%
C - pale, clammy, hypotension, drowsy, coma
Skin - urticaria/angioedema usually but not always present
What is the treatment of anaphylaxis?
Where is it administered?
What is the dose?
IM adrenaline
Administered anterolateral aspect of the middle 1/3 of the thigh
Dose is dependent on the age of the child.
For all adrenaline administration the dose is 1 in 1,000.
<6 months: 150 micrograms (0.15ml)
6M-6Y: 150 micrograms (0.15ml)
6-12Y: 300 micrograms (0.3ml)
>12 years: 500 micrograms (0.5ml)
all 1 in 1000 adrenaline
What is meningitis?
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What test confirms meningitis?
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What types of organisms can cause meningitis?
Which causative organism is the most serious?
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What are the mortality and morbidity figures for meningitis?
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What is the pathophysiology behind the symptoms of meningitis?
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What signs may be suggestive of neck stiffness?
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What things may make up the history of a child with meningitis?
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What things may you see on examination of a child with meningitis?
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What investigations may you consider carrying out if you suspect meningitis?
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What are some contraindications for performing a lumbar puncture in a child who is suspected to have meningitis?
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Focal neurological signs
Papilloedema
Significant bulging of the fontanelle
Disseminated intravascular coagulation
Signs of cerebral herniation
For patients with meningococcal septicaemia a lumbar puncture is contraindicated
If a lumbar puncture is unable to be performed how may the diagnosis of meningitis be obtained?
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Blood cultures and PCR