Embryology general Flashcards
22q11 Deletions are associated with what cardiac defects?
truncus arteriosus, tetralogy of Fallot
Down syndrome is associated with what cardiac defects?
VSD, ASD (ostium primum type), AV septal defect (endocardial cushion defect)
Turner syndrome is associated with what cardiac defects?
Coarctation of the aorta
Cardiac defects in offspring of a diabetic mother?
Transposition of the great vessels
Cardiac defects associated with congenital rubella
Septal defects, PDA, pulmonary artery stenosis
Cardiac defects associated with Marfan syndrome
Aortic insufficiency (late complication)
Cardiac defect associated with fetal alcohol syndrome?
VSD
Treatment for PDA?
indomethacin - Decreases PGE, which maintains patency
4 features of tetralogy of fallot
pulmonic stenosis, right ventricular hypertrophy, VSD, aorta that overrides the VSD
What does the heart looked like on x-ray in tetralogy of fallot?
Boot shaped
What stage eggs arrested in before puberty?
Prophase of meiosis I
saccrococygeal teratomas are thought to arise from what embryonic structure?
Primitive streak
What is the vitelline duct?
connects the yoke sac to the midgut. can persist as Meckel’s diverticulum, which is sort of like an extra appendix in the distal ileum (commonly 30 in from ileocecal valve), and can present with painless brick red bleeding (average age around 2). More common in females
Anterior pituitary germ layer
surface ectoderm
Melanocytes germ layer
Neural crest
Bones of skull germ layer
Paraxial mesoderm
Serious membranes around limbs germ layer
Somatic/parietal lateral mesoderm
gut tube epithelium and glands germ layer
Endoderm
Sensory epithelium: nose, eye, ear germ layer
Surface ectoderm
Lens of eye germ layer
Surface ectoderm
Muscle germ layer
Paraxial mesoderm
Autonomic nervous system germ layer
Neural crest
vertebrae germ layer
Paraxial mesoderm
Three main divisions of paraxial mesoderm
Sclerotome (bone, cartilage), dermatome (dermis, subcutaneous), myotome (muscle)
Two main divisions of lateral mesoderm
Visceral/splachnic and parietal/somatic
Dura mater germ layer
Paraxial mesoderm
Connective tissue germ layer
Paraxial mesoderm
Lungs germ layer
Endoderm
Serious membranes and smooth muscles and connective tissue of viscera germ layer
splanchnic/visceral lateral mesoderm
Body wall germ layer
Somatic/parietal lateral mesoderm
Liver germ layer
Endoderm
Pancreas germ layer
Endoderm
Dorsal root ganglia germ layer
Neural crest
Posterior pituitary (neurohypophysis) germ layer
neuroectoderm
CNS neurons germ layer
Neuroectoderm
Cranial nerves germ layer
Neural crest
Chromaffin cells of adrenal medulla germ layer
Neural crest
Thymus germ layer
Endoderm
Bone germ layer
Paraxial mesoderm
Urogenital system germ layer
Intermediate mesoderm
Parathyroid germ layer
Endoderm
Thyroid follicular cells germ layer
endoderm
enterochromaffin cells germ layer
Neural crest
Pia and arachnoid germ layer
Neural crest
Celiac ganglion, autonomic ganglia
Neural crest
Oligodendrocytes germ layer
neuroectoderm
Parafollicular (C) cells of thyroid germ layer
Neural crest
Epidermis, hair, nails germ layer
surface ectoderm
Astrocytes germ layer
neuroctoderm
Schwann cells germ layer
Neural crest
odontoblasts germ layer
Neural crest
Spleen germ layer
Intermediate mesoderm
Gallbladder germ layer
Endoderm
Laryngeal cartilage germ layer
Neural crest
Bones of face, jaw, and ossicles of ear germ layer
Neural crest
Ependymal cells (glia) germ layer
neuroectoderm
Pineal gland germ layer
neuroectoderm
Postnatal derivative of umbilical vein
ligamentum teres hepatic
Postnatal derivative of umbilical arteries
Medial umbilical ligament
Postnatal derivative of ductus arteriosus
ligamentum arteriosum
Postnatal derivative of ductus venosus
ligamentum venosum
Postnatal derivative of foramen ovale
fossa ovalis
Postnatal derivative of allantois-urachus
Median umbilical ligament
Postnatal derivative of Notochord
Nucleus pulposus of the intervertebral disc
Postnatal derivative of Inferior epigastric artery, vein
Lateral umbilical ligament
Derivative of third aortic arch
Common carotid artery
Derivative of fourth aortic arch
Left – aortic arch, right – proximal part of the right subclavian artery
Derivative of sixth aortic arch
Proximal part of pulmonary arteries, left only – ductus arteriosus
Innervation of first pharyngeal arch
CN V3
Innervation of second pharyngeal arch
CN VII
Innervation of third pharyngeal arch
CN IX
Innervation of fourth pharyngeal arch
CN X
innervation of six pharyngeal arch
Recurrent laryngeal branch of CN X
External auditory meatus is derived from what?
First pharyngeal cleft/groove
Epithelial lining of the palatine tonsil is derived from what?
Second pharyngeal pouch
Inferior parathyroids are derived from what?
Dorsal wings of third pharyngeal pouch
Superior parathyroids are derived from what?
Dorsal wings of fourth pharyngeal pouch
Thymus is derived from what?
ventral wings third pharyngeal pouch
Anterior two thirds of tongue is derived from what?
First pharyngeal arch
Posterior one third of the tongue is derived from what?
Third and fourth pharyngeal arches
What causes DiGeorge syndrome?
aberrant development of the third and fourth pharyngeal pouches
Failure of urachus to close presents as…
Urine leaking from baby’s umbilicus
the forebrain becomes what secondary vesicles?
telencephalon and diencephalon
The forebrain is also called what
prosencephalon
The midbrain becomes what secondary Vesicles?
mesencephalon
Another name for midbrain
mesencephalon
The hindbrain becomes what secondary vesicles?
metencephalon and myelencephalon
Another name for hindbrain
rhombencephalon
Cerebral hemispheres are derived from what
telencephalon
Midbrain is derived from what
mesencephalon
Upper part of the fourth ventricle is derived from what
metencephalon
The cerebral aqueduct is derived from what
mesencephalon
The medulla is derived from what
myelencephalon
The lateral ventricles are derived from what
telencephalon
The thalamus is derived from what
diencephalon
The pons is derived from what
metencephalon
The third ventricle is derived from what
diencephalon
The cerebellum is derived from what
metencephalon
The lower part of the fourth ventricle is direct from what
myelencephalon
the alar plate gives rise to what
Dorsal part of the spinal cord (sensory)
the basal plate gives rise to what
Ventral part of the spinal cord (motor)