Embryology Flashcards

1
Q

Bulbus Cordis

A

Smooth (inflow tracks) of Right and Left Ventricles

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2
Q

What structures are derived from the Endocardial Cushion

A

Atrial Septum, Membraneous intraventricular septum, AV and Semilunar valves

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3
Q

Coronary Sinus

A

Left horn of Sinus Venosus

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4
Q

Inferior Vena Cava

A

Sub-cardinal, Supra cardinal and Posterior cardinal veins

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5
Q

What structures are derived from the Primitive Atrium

A

Trabecular part of the right and left atria

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6
Q

Primitive Pulmonary Vein

A

The smooth part of the left atrium

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7
Q

Primitive Ventricle forms

A

Trabecular part of the Right and Left Ventricles

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8
Q

Right common cardinal and Right Anterior cardinal vein

A

Superior Vena Cava

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9
Q

Right Horn of Sinus Venosus

A

The smooth part of Right Atrium (Sinus Venarum)

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10
Q

Truncus Arteriosus

A

Ascending Aorta and the Pulmonary Trunck

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11
Q

The heart is the first functional organ in vertebrae embryos

A

beats spontaneously by 4 weeks

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12
Q

primary heart tube loops to

A

Establish right-left polarity

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13
Q

Right- Left polarity begins in

A

the 4th week of gestation

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14
Q

Defect in Right- Left Dynein

A

Dextrocardia see in Kartagener syndrome

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15
Q

Kartagener Syndrome

A

primary ciliary Dyskinesia
can have Dextrocardia
due to Defect in Dynein

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16
Q

Atrial Septation

1) Septum Primum
2) Foramen secundum
3) Septum secundum

A

1) Grows towards the endocardial cushion and narrows the foramen primum
2) Forms in the Septum Primum (Foramen Primum disappears )
3a) the Spetum Secumdum develops while the Foramen Secundum maintains R-> L Shunt
3b) Septum Secundum expands to cover most of the foramen secundum
3c) Remaining opening forms the foramen ovale
3d) the remaining portion of septum primum forms the valve of the foramen ovale

17
Q

Foramen ovale

A

Formed by the remaining opening of the foramen secundum

18
Q

The remaining portion of the Septum Primum

A

Forms the valve of the foramen ovale

19
Q

The septum secundum and the Septum Primum fuse to form

A

Atrial Septum

20
Q

Foramen ovale closes soon after birth because

A

There is an increase in pressure in the Left Atrium and decrease pressure in the Right Atrium

21
Q

Patent foramen ovale

A

Due to failure of fusion of the Septum secundum and Septum primum

22
Q

Risk of a patent foramen ovale

A

Migration of a thromboembolic into the systemic arterial circulation

23
Q

Ventricles formation

A

1) muscular Interventricular septum forms
2) The opening present is called the intraventricular foramen
3) Aorticoplumonary septum rotates and fuses with the muscular ventricular septum forming the membranous interventricular septum closing the intraventricular foramen
4) Growth of the Endocardial cushions separates atria from ventricles and contributes to both atrial septation and the membranous portion of the interventricular septum.

24
Q

Most common Congenital Cardiac anomaly

A

Ventricular Septal Defect

25
Q

Most common location of Ventricular Septal Defect

A

Membranous Septum

26
Q

Aorticopulmonary septum rotates and fuses with

A

the membranous ventricular septum

27
Q

Growth of the Endocardial cushion separates the

A

atria from ventricles and contributes to both atrial septation and the membranous portion on the interventricular septum.

28
Q

Outflow Tract formation

A

Neural crest and endocardial cells migrations

  • > truncal ridges and bulbar ridges that spiral and fuses to form the aorticopulmonary septum
  • > ascending aorta and pulmonary trunk
29
Q

Name 3 Conotruncal abnormalities associated with failure of the Neural crest cells to migrate

A

1) Transposition of the Great vessels
2) Tetralogy of Fallot
3) Persistent Truncus Arteriosus

30
Q

Valve development

Aortic and pulmonary valves are derived from

A

The endocardial cushions of the outflow tract

31
Q

Valve Development

Mitral and Tricuspid valves are derived from

A

Fused endocardial cushions of the AV canal

32
Q

Valvular anomalies can be

A

1) Stenotic
2) Regurgitant
3) Atretic (tricuspid atresia)
4) Displaced (Ebstein anomaly)